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Image Steganography in a Karhunen-Loeve Transform Optimization Model
Li-Yangbo,Guo-Zuhua 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.5
In allusion to such problems as large perceptual distortion and high error rate caused by high image compression ratio in existing steganography technology in the information security field, an image Steganography based on Karhunen-Loeve transform optimization is proposed in this paper. Specifically, the iterative clustering algorithm is adopted for this method to solve the covariance matrix and the clustering mean value, and relevant values are adjusted for image segmentation; then, KLT algorithm is introduced to compress the image data and the least significant bit is adopted to replace the ciphertext data for data hiding. During information extraction, the reverse linear transformation operation and the original pixel matrix are adopted to obtain the effective hidden image information. The experiment result shows: compared with common algorithms, the proposed method has improved capacity and PSNR, and the image data extracted thereby has small distortion.
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Yang, Bo,Wang, Yi-Qi,Cheng, Ru-Bin,Chen, Jia-Li,Chen, Jin,Jia, Li-Tao,Zhang, Ru-Song Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11
Background: Our previous study demonstrated cytotoxicity of a crude extract from Patrinia heterophylla Bunge (PHEB). In the present study, we aimed to investigate the effects of isovaltrate acetoxyhydrin (IA) isolated from PHEB on the gastric cancer cell SGC-7901, in order to explore a potential treatment for gastric cancer. Methods: MTT assays were employed to determine the effects of IA on cell vitality and proliferation, with monitoring of cell morphology changes and examination of apoptosis with Annexin V-PI staining. Flow cytometry was used to assess cell cycle progression and mitochondrial membrane potential. The activity of caspase 3, 9 was evaluated by spectrophotometry, and the protein levels of Bax, Bcl2 and Cyclin B1 were analyzed with Western blotting of total proteins extracted from cultured cells. Results: The results demonstrated direct toxicity of IA towards SGC-7901 cells. Evidence of apoptosis included blebbing and chromatin condensation. Annexin V-PI assays revealed early apoptosis, involving rapid depolarization of mitochondrial membranes and activity of caspase 3, 9 signaling pathways. Western blotting showed that Bcl2 and Bax proteins was down- and up-regulated, respectively, and cyclin B1 was up-regulated. Cell cycle analysis further indicated that IA could induce G2/M phase arrest in SGC-7901 cells. Conclusions: In conclusion, we believe that IA induces apoptosis of SGC-7901 cells, therefore providing a potential therapeutic agent for treatment of gastric cancer.
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