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Endocrine-specific NIR fluorophores for adrenal gland targeting
Ashitate, Yoshitomo,Levitz, Andrew,Park, Min Ho,Hyun, Hoon,Venugopal, Vivek,Park, GwangLi,El Fakhri, Georges,Henary, Maged,Gioux, Sylvain,Frangioni, John V.,Choi, Hak Soo The Royal Society of Chemistry 2016 Chemical communications Vol.52 No.67
<P>The adrenal glands (AGs) are relatively small yet require definitive identification during their resection, or more commonly their avoidance. To enable image-guided surgery involving the AGs, we have developed novel near-infrared (NIR) fluorophores that target the AGs after a single intravenous injection, which provided dual-NIR image-guided resection or avoidance of the AGs during both open and minimally-invasive surgery.</P>
Sejung R. Chae,Juhyuk Moon,Seyoon Yoon,Sungchul Bae,Pierre Levitz,Robert Winarski,Paulo J. M. Monteiro 한국콘크리트학회 2013 International Journal of Concrete Structures and M Vol.7 No.2
We report various synchrotron radiation laboratory based techniques used to characterize cement based materials in nanometer scale. High resolution X-ray transmission imaging combined with a rotational axis allows for rendering of samples in three dimensions revealing volumetric details. Scanning transmission X-ray microscope combines high spatial resolution imaging with high spectral resolution of the incident beam to reveal X-ray absorption near edge structure variations in the material nanostructure. Microdiffraction scans the surface of a sample to map its high order reflection or crystallographic variations with a micron-sized incident beam. High pressure X-ray diffraction measures compressibility of pure phase materials. Unique results of studies using the above tools are discussed?a study of pores, connectivity, and morphology of a 2,000 year old concrete using nanotomography; detection of localized and varying silicate chain depolymerization in Al-substituted tobermorite, and quantification of monosulfate distribution in tricalcium aluminate hydration using scanning transmission X-ray microscopy; detection and mapping of hydration products in high volume fly ash paste using microdiffraction; and determination of mechanical properties of various AFm phases using high pressure X-ray diffraction.