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      • KCI등재

        지능형 소프트웨어 정의 인지무선 네트워크의 M&S를 위한 DDPG 기반 트래픽 분산 컨트롤러 설계 및 구현

        이철웅(Cheol-woong Lee),이호진(Hojin Lee),이규민(Gyu-min Lee),이병규(Byungkyu Lee) 한국통신학회 2024 韓國通信學會論文誌 Vol.49 No.8

        컴퓨터의 연산 능력과 무선통신 기술이 향상되면서 다양한 소형 무선 장치들이 등장하였으며, 사물인터넷 기술을 기반으로 하는 다양한 서비스가 출시되었다. 따라서 주파수 자원에 대한 수요가 증가하여, 기존 방식으로는 안정적으로 통신을 수행하기 어려울 만큼 주파수 대역이 포화되었다. 이러한 문제를 극복하기 위해 주파수 자원의 사용 효율 향상을 위한 CR 네트워크 구성 기술들이 제안되었으나, 무선환경 인지를 위해 고려해야 할 요소가 많아 CR 네트워크를 더욱 효과적으로 구성하기 위한 아키텍처가 적용될 필요가 있다. 본 논문에서는 SDN 기술을 지원하는 CR 네트워크 아키텍처를 제안한다. 또한, 제안 구조를 갖는 CR 네트워크에 적용 가능한 DDPG 기반 부하 분산 컨트롤러 아키텍처를 제안한다. 본 논문의 실험결과는 제안하는 컨트롤러가 CR 네트워크의 트래픽을 효과적으로 분산시켜서 주파수 자원이 효율적으로 사용될 수 있음을 보인다. As computer processing power and wireless communication technology have improved, various small wireless devices have appeared, and various services based on Internet of Things technology have been released. Therefore, the demand for frequency resources has increased, and the frequency band has become saturated to the point that it is difficult to perform stable communication using existing schemes. Many configuration technologies for the CR network have been proposed to improve the efficiency of using frequency resources, but since there are many factors to consider for recognizing the wireless environment, an architecture needs to be applied to configure the CR network more effectively. In this paper, we propose a CR network architecture that supports SDN technology. In addition, we propose a DDPG-based load balancing controller architecture applicable to CR networks with the proposed structure. The experimental results in this paper show that the proposed controller effectively distributes traffic in the CR network so that frequency resources can be used efficiently.

      • KCI등재

        Social Network Effects on Post-Traumatic Stress Disorder(PTSD) in Female North Korean Immigrants

        Byungkyu Lee,염유식 대한예방의학회 2011 Journal of Preventive Medicine and Public Health Vol.44 No.5

        Objectives: The goal of this paper is to examine the social network effects on post-traumatic sdress disorder (PTSD) in female North Korean immigrants who entered South Korea in 2007. Specifically, it attempts to verify if the density and composition of networks make a difference after controlling for the network size. Methods: A multivariate logistic regression is used to probe the effects of social networks using the North Korean Immigrant Panel data set. Because the data set had only completed its initial survey when this paper was written, the analysis was cross-sectional. Results: The size of the support networks was systematically related to PTSD. Female North Korean immigrants with more supporting ties were less likely to develop PTSD, even after controlling for other risk factors (odds-ratio for one more tie was 0.8). However, once we control for the size of the network, neither the density nor the composition of the networks remains statistically significant. Conclusions: The prevalence of the PTSD among female North Korean immigrants is alarmingly high, and regardless of the characteristics of supporting network members, the size of the supporting networks provides substantial protection. This implies that a simple strategy that focuses on increasing the number of supporting ties will be effective among North Korean immigrants who entered South Korea in recent years.

      • SCISCIESCOPUS

        WIG1 is crucial for AGO2-mediated <i>ACOT7</i> mRNA silencing via miRNA-dependent and -independent mechanisms

        Lee, Hyung Chul,Jung, Seung Hee,Hwang, Hyun Jung,Kang, Donghee,De, Supriyo,Dudekula, Dawood B.,Martindale, Jennifer L.,Park, Byungkyu,Park, Seung Kuk,Lee, Eun Kyung,Lee, Jeong-Hwa,Jeong, Sunjoo,Han, K Oxford University Press 2017 Nucleic acids research Vol.45 No.11

        <P><B>Abstract</B></P><P>RNA-binding proteins (RBPs) are involved in mRNA splicing, maturation, transport, translation, storage and turnover. Here, we identified <I>ACOT7</I> mRNA as a novel target of human WIG1. <I>ACOT7</I> mRNA decay was triggered by the microRNA miR-9 in a WIG1-dependent manner via classic recruitment of Argonaute 2 (AGO2). Interestingly, AGO2 was also recruited to <I>ACOT7</I> mRNA in a WIG1-dependent manner in the absence of miR-9, which indicates an alternative model whereby WIG1 controls AGO2-mediated gene silencing. The WIG1–AGO2 complex attenuated translation initiation via an interaction with translation initiation factor 5B (eIF5B). These results were confirmed using a WIG1 tethering system based on the MS2 bacteriophage coat protein and a reporter construct containing an MS2-binding site, and by immunoprecipitation of WIG1 and detection of WIG1-associated proteins using liquid chromatography-tandem mass spectrometry. We also identified WIG1-binding motifs using photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation analyses. Altogether, our data indicate that WIG1 governs the miRNA-dependent and the miRNA-independent recruitment of AGO2 to lower the stability of and suppress the translation of <I>ACOT7</I> mRNA.</P>

      • SCOPUSKCI등재

        위식도 역류질환이 있는 기관지확장증 환자에서 양성자 펌프 억제제의 효과

        안병규 ( Byungkyu Ahn ),이동호 ( Dong Ho Lee ),이창민 ( Chang Min Lee ),황재진 ( Jae Jin Hwang ),윤혁 ( Hyuk Yoon ),신철민 ( Cheol Min Shin ),박영수 ( Young Soo Park ),김나영 ( Nayoung Kim ) 대한소화기학회 2016 대한소화기학회지 Vol.68 No.1

        Background/Aims: Bronchiectasis is aggravated by gastroesophageal reflux disease (GERD) owing to micro aspiration. Some researchers note the effect of antireflux surgery in bronchiectasis with GERD. However, few have investigated the effects of medical antireflux therapy. We investigated the effect of proton pump inhibitors (PPIs) in bronchiectasis with GERD. Methods: From March 2003 to May 2015, the clinical records of patients who had bronchiectasis with GERD were reviewed. Patients underwent an initial pulmonary function test (PFT) and chest computed tomography when diagnosed with bronchiectasis. One group with typical GERD symptoms was treated with PPIs, while the other group was not. Both groups underwent PFTs within six months after completing PPI therapy. Population characteristics and associations were compared between the groups. Results: Two hundred and fifty-seven patients (124 male, 133 female; mean age 67.6±10.0 years) were included. There were no significant differences between the groups in terms of forced vital capacity (FVC; p=0.239), forced expiratory volume in one second (FEV1; p=0.555), or FEV1/FVC (p=0.374) after PPI therapy. However, there were significant improvements in FVC (p=0.002) and FEV1 (p=0.006) in patients with high BMI in the PPI treatment group. Conclusions: PPIs have no effect on the pulmonary function in patients with bronchiectasis and GERD. However, PPIs were noted to produce improvements in lung function in patients with bronchiectasis and high BMI. (Korean J Gastroenterol 2016;68:10-15)

      • KCI등재

        중개 위치 점유의 증가와 감소에 관한 연구

        이병규(Byungkyu Lee),염유식(Yoosik Youm) 한국사회학회 2012 韓國社會學 Vol.46 No.4

        이 연구는 완전 연결망(global network)이면서 동시에 시계열 자료를 확보할 수 있는 장점을 지닌 국회의원 간 대표 발의 연결망 자료를 이용하여 중개 위치를 점유하는 횟수가 증가 또는 감소하는 과정을 검토하였다. 그동안 중개자가 어떤 이득을 취하는지에 대한 연구는 많았지만, 그 이득을 내는 행위자가 고정되어 있는지 아니면 여러 행위자가 번갈아 중개자의 위치를 점유하는지에 대한 연구가 상대적으로 적었으며, 이에 이 연구는 ?중개 위치 점유?를 중심 주제로 초점을 맞추었다. 특히 우리는 시계열자료와 이원 고정효과 패널회귀모형(two-way fixed effect panel regression model)을 통해 중개자 위치를 차지하는 데 필요한 (관찰되지 않으며 고정되어 있는) 개인적인 속성을 통제한 후 이전 시기의 대표 발의 연결망에서의 중개 위치의 점유가 다음 시기의 중개 위치 점유에 미치는 순수한 효과를 살펴보았다. 17대 대한민국 국회의 대표 발의 연결망을 바탕으로 연구한 결과는 크게 다음의 두 가지로 요약된다. 첫째, 중개자 점수는 다음 시기의 중개자 점수에 부정적인 효과를 보였다. 중개 위치를 점유한 경우에 계속해서 그 위치를 유지하기가 어려울 뿐만 아니라 다음 시기의 중개 위치를 점하는 데 도리어 방해가 되었다. 둘째, 이러한 효과는 시기별 정치적 갈등과 강한 상호작용을 보였으며 그 상호작용의 형태는 종 모양(inverse U-shape)을 띄었다. 일반적으로 중개 위치의 선점은 그 다음 시기의 중개 위치 점유에 부정적인 영향을 미치지만 정치적 갈등이 약하거나 심한 경우에 그 부정적인 영향이 극대화되었고, 정치적 갈등이 중간 수준인 경우에는 부정적인 영향이 극소화됨을 확인할 수 있었다. 심지어 법안 가결률이 중간 수준인 43%일 때는 매우 소폭이긴 하지만 긍정적 효과를 보였다. 이는 정치적인 장에 있어 중개 받는 타자(alter)들 사이에 존재하는 갈등 상황이 너무 약하거나 너무 강하면 그 중개의 영향이 극소화 된다는 점을 시사한다. 이러한 결과는 정치적인 연결망을 포함하여 일반적인 사회 또는 경제연결망에서 중개 위치의 효과를 연구할 때 중개 위치의 효과뿐만 아니라 ?중개대상자들 사이에 존재하는 갈등이나 신뢰정도?에도 주의를 기울여야 할 필요성이 있음을 함의한다. This paper examined the brokerage decays by using the sponsorship network of bills in the 17th Korean National Assembly that is both longitudinal and global (or complete). While most of previous studies examined the benefits of brokerage, there have relatively few studies that probed if the same actors repeatedly occupy brokerage positions or different actors take turns occupying the positions. Especially, we examined the net effect of taking a brokerage position at time (t) on the taking a brokerage position at time (t+1) after controlling for observed and unobserved heterogeneity between individual congressman by using two-way fixed effect panel regression model. Two important findings were revealed. First, the brokerage score at time (t), which measured how many times the actor occupies the brokerage position in a network, had negative effect on the brokerage score at time (t+1). Second, the negative effect was contingent on the amount of political tension during the period the co-sponsored bill was proposed. When the political tension measured by bill-pass rates is extremely low or very high, the negative effect reached the maximum while the negative effect was the lowest when the tension was at medium level: inverse-U shape.

      • KCI등재

        미국 제약업의 특허 네트워크 분석을 통한 기업수준에서의 혁신성과의 결정요인 탐색

        이병규 ( Byungkyu Lee ) 한국지식재산연구원 2009 지식재산연구 Vol.4 No.1

        Innovation through R&D is considered as a main factor of constant and competitive growth of firms (Brusoni, 2005). Although most of innovation studies reveal that R&D increases the firm’s innovation output, the mechanism of link between R&D and innovation output is still unclear. This study tries to open the black box of innovation process in the firm level by analyzing data on 6,384 patents pended by top 10 pharmaceutical companies from 2001 to 2005. The inventors’ collaborative network of knowledge sharing will have an impact on the creation of patents as an innovation output because patents are produced by inventors. With the same resources such as R&D expenditures, some firms will have marginal benefits resulting from the shape and structure of the inventors’collaboration network. In this study, we hypothesized that the innovation output will be produced in the “weak” structure rather than in the cohesive and dense network because in the cohesive and dense network actors exploit resources and information, and their subsequent innovation comes from exploration rather than from exploitation. The results partially supported our hypothesis: after controlling for the R&D expenditure, the degree centralization and the betweeness centralization of the network has a negative and significant impact on the subsequent number of patents, but the network density has a negative and insignificant impact on the subsequent number of patents. The implication of this study is that for the purpose of increasing the innovation output, such as increasing the number of patent, firms should try to make the inventors’network to be decentralized and flexible so that inventors can have an opportunity to seek new knowledge.

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