췌장 선방세포암 1예

이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

지역불균형 시각에서 인천경제자유구역과 원도심과의 상호작용 분석: 인천시 중구, 연수구 및 서구를 중심으로

정진원(Jung, Jin-Won),최민아(Choi, Min-A) 인천발전연구원 2021 도시연구 Vol.- No.19

본 연구는 지역불균형 시각에서 인천경제자유구역과 각 자치구 원도심과의 상호작용 분석을 실시하였다. 지역의 경제성장과정에서 불균형 발전을 논한 A. Hirschman과 G. Myrdal은 경제발전 초기에는 성장 잠재력이 높은 거점지역이 주변지역의 많은 경제활동들을 흡수하는 분극화(역류) 효과 이후 누적(파급)효과가 나타는데 A. Hirschman은 불균형 발전의 완화를 가져온다고 주장하는 반면, G. Myrdal은 불균형 발전의 누적적 가속화가 진행된다고 주장한다. 2003년 인천경제자유구역 지정이후 18년 가량 지난 시점에서 각 자치구와의 경제요소간 상호작용 분석 결과, 인천경제자유구역 각 지구와 자치구 원도심간의 불균형 발전이 심화되는 것으로 나타났다. 이러한 불균형 발전을 완화하기 위해, 중구 원도심 활성화, 서구 및 연수구 원도심의 정주성 제고, 보행친화적 연계를 위한 공간계획 수립 및 IFEZ에서 원도심으로 파급효과를 야기할 수 있는 산업경제정책 마련 등이 필요함을 제시하였다. This study analyzed the interaction between the Incheon Free Economic Zone (IFEZ) and the old downtown of each autonomous district from a perspective of regional imbalance. In discussing uneven development in the economic growth process of a region, Hirschman and Myrdal argue that in the early stages of economic development, a regional base with high growth potential has a trickle-down (spread) effect after the polarized (back-wash) effect in that it absorbs a lot of economic activities from surrounding areas. However, while Hirschman argues that this mitigates uneven development, Myrdal argues that cumulative acceleration of uneven development continues. About 18 years after the designation of the IFEZ in 2003, this analysis of the interaction between economic factors of each autonomous district revealed that uneven development between each district of the IFEZ and the old downtowns of autonomous districts has been deepening. To alleviate this uneven development, this study suggested the necessity to revitalize the old downtown of Jung-gu, enhance the settlement of the old downtowns of Seo-gu and Yeonsu-gu, establish a space plan for pedestrian-friendly connections, and prepare industrial economic policies that can bring trickle-down effects from IFEZ to old downtowns, and so on.

우리나라 일부 석면사업장의 석면폐 유병률

백도명,백남원,최정근,손미아,임정기,이원진,문영한,박정선,최병순 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

Asbestos industry has been in operation over 60 years in Korea. However, the prevalence of asbestosis has not been yet reported. With rapid turn-over of workers, previous cross-sectional studies of current workers on the job could not find cases with exposures long enough for the development of asbestosis. This study was done to evaluate asbestosis prevalence of those worksites with operation history of more than 20 years. In total, 139 workers from 5 worksites were examined. Asbestos industries covered in the study include 2 asbestos textile, 1 brake lining, and 2 ship repairing worksites. Chest x-ray was taken from all workers and read by two experts familiar with pneumoconiosis classification according to 1980 ILO guidelines. Those with findings compatible with asbestosis were further ckecked with high resolution computerized tomography (HRCT). Pulmonary function tests were done according to ATS guidelines, and occupational and previous medical history was taken through a standardized interview. Air-borne asbestos was measured according to NIOSH method 7400. The air-borne asbestos concentrations ranged from 0.2-1.3 f/cc for asbestos textile, from 0.7-1.0 f/cc for brake lining, and from 6.3-7.8 f/cc during asbestos removal at ship repairing worksite. Of the 139 workers 25 had abnormal chest radiographic findings, and 10 of them had findings compatible with pneumoconiosis. When work history and current asbestos measurements were accounted, 9 workers who had more than 10 years of asbestos exposure history showed chest radiographic findings of pneumoconiosis with Finally, 4 workers showed finding of pulmonary fibrosis and/or pleural thickening at HRCT, and 2 of them had restrictive lung function changes. The study results showed that, among 139 subjects, there were 4(3%) definite asbestosis cases confirmed with HRCT. The prevalence of probable asbestosis was 7% for 10-14 years of exposure, 13% for 15-19 years of exposure, and 23% for 20 or more years of exposure. The prevalence of compensable asbestosis with abnormal lung function was 4-6% for those with 15 or more years of exposure.

원발성 후복막 점액낭샘암종 1예

지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

청소년의 스마트폰 중독과 우울 및 불안과의 관계

김경은,김필송,민주연,박수경,신서인,이지은,정해인,조호정,최정원,최정인 이화여자대학교 간호과학대학 2013 이화간호학회지 Vol.- No.47

Purpose: The purpose of this study was to investigate the relationships between the degree of smart phone addiction among adolescents and their depression and anxiety levels. Method: In this study, 379 high school students were selected using the convenient sampling method. The instruments used for this study were smart phone addiction measure, the CES-D (Center for Epidemiological Studies-Depression Scale), and the STAI (State-Trait Anxiety Inventory). Data were analyzed using the SPSS 20.0 program with descriptive statistics, t-test, ANOVA with Scheffe test, and Pearson’s correlation coefficient. Result: The mean score for smart phone addiction was 40.45±17.27, depression was 36.56±9.58, state anxiety was 44.00±9.61, and trait anxiety was 45.70±9.75. There were significant differences between the degree of smart phone addiction and the following variables: gender (t=-4.953, p<.001), hours of smart phone use per day (F=12.259, p<.001), types of frequently used features (F=3.485, p=.008), and satisfaction level for smart phone (F=5.18, p<.001). There were statistically significant relationships (p<.001) among degree of smart phone addiction, depression level, and state and trait anxiety levels. Conclusion: The results of this study suggested that there was a significant relationship between smart phone addiction and mental health, specifically, depression and anxiety among adolescents. Further research is needed to develop nursing strategies to provide care for adolescents who frequently utilize smart phones.

우리나라 노인여성의 골다공증성 척추골절로 인한 경제적 부담 추계

강혜영,강대룡,장영화,박성은,최원정,문성환,양규현,Kang, Hye-Young,Kang, Dae-Ryong,Jang, Young-Hwa,Park, Sung-Eun,Choi, Won-Jung,Moon, Seong-Hwan,Yang, Kyu-Hyun 대한예방의학회 2008 예방의학회지 Vol.41 No.5

Objectives : To estimate the economic burden of osteoporotic vertebral fracture (VF) from a societal perspective. Methods : From 2002 to 2004, we identified all National Health Insurance claims records for women ${\geq}50$ years old with a diagnosis of VF. The first 6-months was defined as a "clearance period," such that patients were considered as incident cases if their first claim of fracture was recorded after June 30, 2002. We only included patients with ${\geq}$ one claim of a diagnosis of, or prescription for, osteoporosis over 3 years. For each patient, we cumulated the claims amount for the first visit and for the follow-up treatments for 1 year. The hospital charge data from 4 hospitals were investigated to measure the proportion of the non-covered services. Face-to-face interviews were conducted with 106 patients from the 4 study sites to measure the out-of-pocket spending outside of hospitals. Results : During 2.5 years, 131,453 VF patients were identified. The patients had an average of 3.38 visits, 0.40 admissions and 6.36 inpatient days. The per capita cost was 1,909,690 Won: 71.5% for direct medical costs, 20.6% for direct non-medical costs and 7.9% for indirect costs. The per capita cost increased with increasing age: 1,848,078 Won for those aged 50-64, 2,084,846 Won for 65-74, 2,129,530 Won for 75-84and 2,121,492 Won for those above 84. Conclusions : Exploring the economic burden of osteoporotic VF is expected to motivate to adopt effective treatment options for osteoporosis in order to prevent the incidence of fracture and the consequent costs.

디젤 乘用車輛에서 DPF 條件에 따른 極微細粒子의 排出 特性에 關한 硏究

鄭珉元,崔源鶴,柳鍾植,李海喆,車京玉 明知大學校 産業技術硏究所 2008 産業技術硏究所論文集 Vol.27 No.-

Recent1y, the nano-PM(Particulate Matters) number concentration emitted by diesel internal combustion engine has focused on attention because this nano-PM is suspected being hazardous of human health. In this study, the PM of the diesel passenger vehicles were investigated by number concentration. A condensation particle counter (CPC) system was used to measure the particle number concentration and size of diesel exhaust particles at the end of dilution tunnel during the NEDC(ECE15+EUDC) vehicle test mode using light-duty diesel passenger vehicles with DPFs. As a research result, the characteristic of DPF performance about diesel nano-particle number concentration and size distribution was investigated in this study.

자바 가상 기계를 목적으로 하는 C컴파일러 설계

최원호,정민수,김도우 경남대학교 정보통신연구소 1999 연구논문집 Vol.1 No.-

요즘 각광 받고 있는 정보통신 분야에서는 무선 네트워킹, 홈 네트워킹, 오피스 네트워킹 등 특정한 플랫폼과 네트웍 디바이스에 상관없이 서로 정보를 주고 받고 있다. 그리고 일반 가정에서도 쉽게 디지털 TV나 휴대폰 등에서 인터넷에 접속하여 정보를 얻을 수 있다. 이런 서로 다른 이기종 플랫폼에 영향을 받지 않고 사용할 수 있는 것이 바로 자바이다. 본 논문에서는 자바만이 가지는 플랫폼 독립적인 특성을 C언어와 같은 고급 언어에 적용해 보고자 한다. 이를 통해서 기존 C언어로 작성된 소프트웨어를 본 논문에서 설계한 컴파일러를 통해 소프트웨어의 재사용성을 높이면서 자바만의 특성을 가지게 할 수 있다. 즉, C언어로 작성된 원시 코드(Source code)를 컴파일러를 이용해서 자바 가상 기계가 인식할 수 있는 목적 코드인 바이트 코드(Byte code)로 변환하고 이를 자바 가상 기계(Java Virtual Machine)가 탑재되어 있는 어떠한 플랫폼에서도 수행할 수 있도록 하는 것이다. 따라서, 본 논문에서는 C언어로 작성된 응용 프로그램을 이기종 플랫폼 상에서 실행 가능 하도록 바이트 코드를 생성하는 컴파일러를 설계한다. The platform independence is the hot issues in the world information and communications, such as wireless networking, Home networking, Office networking. Java is an solution of platform independence. In this paper, we apply the platform independence features of Java to high level language, such as C. In other words, we design a compiler that reads C code and produce bytecodes. Hence, the software written C can be translated into bytecode and can be executed under Java virtual machine.

신상아에서 후족부 모세 혈액 검사 이후에 발생한 종골 골수염

최장석,김정원 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

In neonate, osteomyelitis of the calcaneus is extremely rare and various reports have indicated that it accounts for 3~8% of all bone infections among neonates, infection can result from hematogenous seeding or direct inoculation, as seen in puncture wounds (accidental or for blood sampling), open fracture, degloving injuries. and extension of pressure ulceration. Although direct inoculation has been reported to be the more frequent cause, other reports suggest a hematogenous etiology in the majority. We compared our experience that neonate calcaneal osteomyelitis after hind foot capillary blood sampling for cogenital metabolic deficiencies test and follow up of bilirubin level at Paik Hospital, Inje University, Pusan, Korea to that reported in the literature to determine if the experience at this institution was similar to that previously reported. Additionally, characteristics of the clinical presentation, laboratory investigation, treatment, and outcome were studied to determine if any factors might be helpful in making an earlier diagnosis, improving outcome, or both.

FK506의 열린 고리 유도체와 FKBP와의 결합체의 결정구조 분석

최정원 수원대학교 자연과학연구소 2000 자연과학논문집 Vol.3 No.-

The crestal structure of ring opened FK506 analogue complexed with FKBP12 has been determined at 1.9 ? resolution. The overall view of the complex is exactly the same as the FKBP12-FK506 complex. All of the interactions between the FKBP12 and FK506 analogue also shows the same architecture with the FKBP12-FK506 complex, which is correspondent with the binding affinity of FK506 analogue. Recently, FKBP12 has been identified as a target for the promotion of neurite outgrowth and neurotrophic and neuroprotective effects could be associated with the action of different FKBP12 ligands. This structure may play an important role in the drug design for the new neuroregenerative agents.