21st Century Learning Skills: A Challenge in Every Classroom

Joseline M. Santos ASCONS 2017 INTERNATIONAL JOURNAL OF EMERGING MULTIDISCIPLINAR Vol.1 No.1

The main objective of this study is to assess the 21st century learning skills of the students and the teaching practices in the 21st century classroom. Specifically, the study sought answers to the following questions: 1) How may the 21st century learning skills of the students be described in terms of eight (8) components of the 21st century learning skills? 2) How may the teaching practices be described in terms of 21st century learning skills? 3) Is there a significant relationship between the perception of the students on their acquired 21st century learning skills and the teaching of 21st century learning skills in the classroom based on the perception of the teachers? 4) What is the implication of this study to the teachers, students and administrators of BulSU-CoEd? This study used a descriptive method of research. Data were gathered and analyzed. Student-t and Pearson r product moment were used to test the hypothesis between the difference in the perceptions of the two groups of respondents and the relationship between them. Mean was also used to describe the summary of the questionnaire. The topmost skills of the students are; using technology as a tool for learning, self-direction skills, and collaboration. The topmost teaching practices are; local connections, creativity and innovation skills, and using technology as a tool for learning. The results indicated that the students’ perception on the 21st Century skills that they acquired are not the same as what the teachers perceived to be what they transferred. This research could serve as a basis for the seminars and workshops that may be provided to staff in-house or external.

얼굴 검출을 위한 캐스케이드 CNN 정확도에 관한 연구

우위네마조세린 ( Uwinema Joseline ),이해연 ( Hae-yeoun-lee ) 한국정보처리학회 2018 한국정보처리학회 학술대회논문집 Vol.25 No.1

Convolutional Neural Network is arguably the most popular deep learning architecture that is one of the most attractive area of research since it has various applications including face detection and recognition. The cascaded CNN operates at multiple resolution and rejects the background regions in the fast low resolution stages. By considering that advantage, we carry out the study on accuracy of cascaded CNN for face detection applications. The key point for our study is to analysing and improving the accuracy of cascaded CNN by applying simulations of algorithm where by we used Google's Tensorflow GPU as deep learning framework.

Maturation Phenotype of Peripheral Blood Monocyte/Macrophage After Stimulation with Lipopolysaccharides in Irritable Bowel Syndrome

( Oscar A Rodriguez-fandino ),( Joselin Hernandez-ruiz ),( Yolanda Lopez-vidal ),( Luis Charua-guindic ),( Galileo Escobedo ),( Max J Schmulson ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2017 Journal of Neurogastroenterology and Motility (JNM Vol.23 No.2

Background/Aims Abnormal immune regulation and increased intestinal permeability augmenting the passage of bacterial molecules that can activate immune cells, such as monocytes/macrophages, have been reported in irritable bowel syndrome (IBS). The aim was to compare the maturation phenotype of monocytes/macrophages (CD14+) from IBS patients and controls in the presence or absence of Escherichia coli lipopolysaccharides (LPS), in vitro. Methods Mononuclear cells were isolated from peripheral blood of 20 Rome II-IBS patients and 19 controls and cultured with or without LPS for 72 hours. The maturation phenotype was examined by flow cytometry as follows: M1-Early (CD11c⁺CD206^-), M2-Advanced (CD11c^-CD206⁺CX3CR1⁺); expression of membrane markers was reported as mean fluorescence intensity (MFI). The Mann-Whitney test was used and significance was set at P < 0.05. Results In CD14+ cells, CD11c expression decreased with vs without LPS both in IBS (MFI: 8766.0 ± 730.2 vs 12 920.0 ± 949.2, P < 0.001) and controls (8233.0 ± 613.9 vs 13 750.0 ± 743.3, P < 0.001). M1-Early cells without LPS, showed lower CD11c expression in IBS than controls (MFI: 11 540.0 ± 537.5 vs 13 860.0 ± 893.7, P = 0.040), while both groups showed less CD11c in response to LPS (P < 0.01). Furthermore, the percentage of “Intermediate” (CD11c⁺CD206⁺CX3CR1⁺) cells without LPS, was higher in IBS than controls (IBS = 9.5 ± 1.5% vs C = 4.9 ± 1.4%, P < 0.001). Finally, fractalkine receptor (CX3CR1) expression on M2-Advanced cells was increased when treated with LPS in controls but not in IBS (P < 0.001). Conclusions The initial phase of monocyte/macrophage maturation appears to be more advanced in IBS compared to controls. However, the decreased CX3CR1 in patients with IBS, compared to controls, when stimulated with LPS suggests a state of immune activation in IBS. (J Neurogastroenterol Motil 2017;23:281-288)

Hydrogen bonding interactions on 1H-1,2,3-triazole based crystals: Featuring experimental and theoretical analysis

P. Muthuraja,T. Joselin Beaula,M. Sethuram,V. Bena Jothy,M. Dhandapani 한국물리학회 2018 Current Applied Physics Vol.18 No.6

Two triazole crystals, namely 1H-1,2,3-triaol-3-ium 2,4,6-trinitrophenolate (TZP) and 1H-1,2,3-triazole: 3,5- dinitrobenzoic acid (TZDBA) were investigated by using DFT and TD-DFT methods to identify the nature and influence of molecular interactions on properties of the compounds. Spectroscopic analyses were carried out to confirm the molecular entities in both the compounds. Optimization of the molecular structure was undertaken using three different DFT combinations of functionals. UV spectral analysis was carried out both experimentally and theoretically. CHELPG atomic charges, HOMO-LUMO and NBO analyses reveal the effect of deprotonation in TZP and formation of molecular adduct in TZDBA. Thermal analysis reveals both the compounds were stable up to 160 °C. Both the triazole derivatives belong to soft material category. The intermolecular hydrogen bonding interactions in TZP and TZDBA are responsible for the observed molecular hyperpolarizabilities. There is an increase in the frequency dependent hyperpolarizabilities compared to the static hyperpolarizabilities.

From Cytokines to Toll like Receptors and Beyond Current Knowledge and Future Research Needs in Irritable Bowel Syndrome

( Max Schmulson ),( Oscar Rodriguez Fandino ),( Joselin Hernandez Ruiz ) 대한소화관운동학회 2010 Journal of Neurogastroenterology and Motility (JNM Vol.16 No.4

The irritable bowel syndrome (IBS) is a complex disorder in which psychosocial, cultural and biological factors, interact. Recent knowledge in the pathophysiology of IBS, seem to combine issues such as a low grade inflammation or immune activation and dysbiosis that can trigger or exacerbate IBS. On the other hand, stress mediated through the hypothalamic-pituitary-adrenal axis can produce motility abnormalities that can modify the microbiota as well, with the subsequent immune activation in the mucosa and stimulation of nerve terminals, generating symptoms of IBS. Also, we speculate that, stress, dysbiosis or an underlying genetic predisposition, may increase the epithelial permeability leading to a contact between pathogens-associated molecular patterns and toll-like receptors in the deeper layers of the gut, developing a host immunity response and IBS generation. We believe that the role of toll-like receptors in IBS and elucidating the communication processes between the immune and the nervous system, warrant future research.

DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.

Aleyasin, Hossein,Rousseaux, Maxime W C,Marcogliese, Paul C,Hewitt, Sarah J,Irrcher, Isabella,Joselin, Alvin P,Parsanejad, Mohammad,Kim, Raymond H,Rizzu, Patrizia,Callaghan, Steve M,Slack, Ruth S,Mak, National Academy of Sciences 2010 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.107 No.7

<P>Loss-of-function DJ-1 (PARK7) mutations have been linked with a familial form of early onset Parkinson disease. Numerous studies have supported the role of DJ-1 in neuronal survival and function. Our initial studies using DJ-1-deficient neurons indicated that DJ-1 specifically protects the neurons against the damage induced by oxidative injury in multiple neuronal types and degenerative experimental paradigms, both in vitro and in vivo. However, the manner by which oxidative stress-induced death is ameliorated by DJ-1 is not completely clear. We now present data that show the involvement of DJ-1 in modulation of AKT, a major neuronal prosurvival pathway induced upon oxidative stress. We provide evidence that DJ-1 promotes AKT phosphorylation in response to oxidative stress induced by H(2)O(2) in vitro and in vivo following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment. Moreover, we show that DJ-1 is necessary for normal AKT-mediated protective effects, which can be bypassed by expression of a constitutively active form of AKT. Taken together, these data suggest that DJ-1 is crucial for full activation of AKT upon oxidative injury, which serves as one explanation for the protective effects of DJ-1.</P>