실리콘 제조공정 폐수 중 킬레이트 수지를 이용한 고농도 Zn 제거에 관한 연구

신종은 ( Jongeun Shin ),홍종현 ( Jonghyun Hong ) 한국물환경학회(구 한국수질보전학회) 2019 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2019 No.-

Efficacy of photobiomodulation therapy for the prevention of radiodermatitis in patients with breast cancer: A single institution explorative study

( Jongeun Lee ),( Dongmin Shin ),( Donghwi Jang ),( Hyun Jeong Byun ),( Se-jin Oh ),( Hyun Je Kim ),( Ji-hye Park ),( Jong-hee Lee ),( Won Park ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Radiotherapy (RT) may accompany acute skin reactions from mild erythema to confluent moist desquamation and ulceration. Objectives: We aimed to evaluate the effectiveness of PBMT in the prevention of acute radiodermatitis in breast cancer patients undergoing RT. Materials and methods: This study was a single-blinded prospective trial. The subjects were divided into three groups -control group (PBMT not done, n=10), group 1 (633nm, n=16), and group 2 (830nm, n=16). PBMT was performed 3 times a week from the 4th week of RT up to a week after the end of RT. Common Terminology Criteria for Adverse Events grade and skin measurements (melanin, erythema, moisture, and sebum content index) were evaluated at four different time points - before RT (V0), after 3 weeks of RT (V1), after the end of RT (V2), and 1 month after completion of RT (V3). Results: In the control group, 7 patients (77.8%) developed grade 1 reactions and 2 (22.2%) patients grade 0 at V3. In group 2, all patients presented grade 0 at V3. Group 1 had less melanin difference between irradiated and non-irradiated breasts from baseline compared to the control group at V3 (p=0.0004). Both group 1 and 2 showed greater increased level of moisture index from baseline at V3 than the control group. For sebum index, control group showed lower sebum level at V2 compared to group 2 and at V3 compared to group 1 and 2. Conclusion: Both wavelengths (633nm and 830nm) of PBMT are effective for the prevention of acute radiodermatitis.

A case of recurrent fever and skin rash in Blau syndrome

( Jongeun Lee ),( Yeonjoo Jung ),( Dong Min Shin ),( Donghwi Jang ),( Se Jin Oh ),( Ji-hye Park ),( Jong Hee Lee ),( Joo-heung Lee ),( Dongyoun Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.72 No.2

Blau syndrome was first described in 1985 as a familial granulomatous inflammatory disease with autosomal dominant inheritance pattern. It is caused by mutation in NOD2 gene, a member of the NOD-like receptor (NLR) family of pattern recognition receptors, which is involved in inflammation and innate immune defense against invading pathogens. A 14-month-old boy presented with erythematous papules on whole body with recurrent fever since 1 month after birth. Along with recurrent fever and rash, there was moderately reduced result of neutrophil respiratory burst test and decrease in memory T-cell and B-cell in lymphocyte subset study. The skin biopsy specimen of his abdomen demonstrated multifocal non-caseating granulomas with some giant cells. After mutation analysis, it revealed NOD2 c.1000c>t p(Arg334Trp) heterozygous, de novo mutation. Blau syndrome classically presents in early childhood and presents the triad of granulomatous polyarthritis, dermatitis and uveitis Skin rash is the first symptom to appear usually in the first year of life. Erythematous maculo-micropapular fine scaly rash on the trunk and extremities in infant is often misdiagnosed as atopic dermatitis or ichthyosis vulgaris. Herein, we present a case of Blau syndrome which presented recurrent fever and erythematous papular skin rash in young child.

소아 흉터 환자에서 초기 레이저 치료의 유용성에 관한 후향적 단일기관 연구

이종은 ( Jongeun Lee ),신동민 ( Dong Min Shin ),장동휘 ( Donghwi Jang ),오세진 ( Se Jin Oh ),김현제 ( Hyun Je Kim ),이종희 ( Jong Hee Lee ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.7

Background: Scars in children are highly concerning to most parents who usually seek prompt treatment for these lesions. However, compared with adults, children show a greater tendency to develop hypertrophic scars and a higher likelihood of scar widening with increasing age. Objective: We investigated the role of laser treatment for scars in pediatric patients in view of the fact that this approach is challenging in this age group. Methods: This retrospective study included patients aged <17 years who visited the Samsung Medical Center between 2013 and 2018 for scar treatment. Of the 28 children who visited the center during this time, 14 presented within 4 to 5 weeks from scar onset and received laser therapy and 14 presented after 4 to 5 weeks and received topical treatment. The Stony Brook Scar Evaluation Scale (SBSES) was used to assess scar formation. Results: The mean initial SBSES scores were lower in the laser than in the topical group (1.93±0.92 vs. 2.71±0.83, p=0.0363). No intergroup difference was observed in SBSES scores upon treatment completion (4.50±0.94 vs. 4.21±1.19, p=0.4673). Multivariable analysis after adjustment for age, sex, and initial SBSES scores showed that the type (laser vs. topical) of treatment was not significantly associated with an SBSES score=5 or duration of treatment. Conclusion: Laser intervention may be useful for scar therapy in children who present early and can receive prompt treatment before scar maturation; however, further studies are warranted to validate our results. (Korean J Dermatol 2021;59(7):507∼512)

보안프로그램의 현저성이 온라인 서비스 평가에 미치는 영향: 소비자 마음가짐의 조절효과를 중심으로

박종은 ( Jongeun Park ),허다경 ( Dakyeong Heo ),신동우 ( Dongwoo Shin ) 한국소비자학회 2015 소비자학연구 Vol.26 No.3

온라인 서비스 제공자들은 전자상거래 과정에서 소비자들이 느끼는 불안감을 해소하기 위한 방안으로 다양한 형태의 안전표시(safety cue)를 사용하고 있다. 본 연구에서는 목적추구 과정(goal striving process)에 대한 소비 자의 마음가짐(mind-sets) 이론에 근거하여 온라인 금융거래상황에서 나타나는 안전표시들이 소비자들에게 심리적인 안정을 가져오기도 하지만 소비자들의 특성과 안전표시의 형태에 따라서 거래과정의 안전성에 대한 우려를 증폭시키는 역효과를 가져올 수 도 있음을 보이고자 한다. 이를 위해서 안전표시의 현저성(높음 vs. 낮음)과 소비자가 가지는 마음가짐(실행 마음가짐 vs. 신중 마음가짐)의 상호작용에 관한 가설과 이러한 상호작용의 효과가 소비자가 느끼는 지각된 위험을 통하여 전달되어 결과적으로 서비스 평가에 영향을 미칠 것이라는 지각된 위험의 매개효과에 대한 가설을 함께 도출하였다. 가설 검정과정에서는 기존 연구에서 온라인 서비스 평가에 영향을 미치는 중요 변수로 사용되었던 컴퓨터 효능감(computer efficacy)을 통제변수로 활용하였다. 제시된 가설을 분석하기 위하여 안전표시의 현저성을 조작한 가상의 금융서비스 웹사이트를 구성하여 획득한 실험 자료를 일련의 회귀분석을 이용하여 분석하였다. 분석결과를 살펴보면, 신중 마음가짐을 가진 소비자는 금융거래상황에서 안전표시들의 현저성이 높은 상황에서 오히려 더 심리적인 불안감을 느껴 서비스에 대한 부정적인 평가를 내리는 반면, 실행 마음가짐을 가진 소비자는 안전표시들이 뚜렷이 나타나지 않는 거래상황에서 심리적 불안감을 크게 느껴 부정적인 평가를 내리는 것으로 나타났다. 통제변수로 사용되었던 컴퓨터 효능감이 높은 소비자는 안전표시의 현저성이 높은 경우에 더 높은 심리적 불안감을 경험하고 부정적인 평가를 내린 반면 컴퓨터 효능감이 낮은 소비자는 안전표시의 현저성이 낮은경우 더 높은 심리적 불안감을 느끼고 부정적 평가를 내린 것으로 나타났다. 또한 매개변수로 사용된 지각된 위험은 소비자 마음가짐과 컴퓨터 효능감이 안전표시의 현저성과 가지는 두 개의 상호작용효과를 모두 서비스평가에 매개하는 것으로 나타났다. In recent years, online service providers have enjoyed constant growth in financial transactions in online market place. Recent development in mobile shopping applications further encourages consumers to purchase their various products and services through online/mobile financial transaction system. However, many consumers, who witnessed recent security breaches and informational leaks from major retailers and financial institutes in Korea, are also growing concerns over the safety of online financial transactions. To lessen consumers’ anxiety of using online payment system, Korean online service providers implement prominent safety cues - pop-up windows and other visible statements guaranteeing secure online financial transaction. Although many academicians and practitioners have extensively discussed the technical aspects related to the security of such transaction systems, there has been virtually no attempt to understand how prominent safety cues influence consumers’ psychological processes and risk perceptions. Based on the theory of implemental/deliberative mind-set in consumers’ goal pursuit process (Gollwitzer and Bayer 1999), we developed a series of hypotheses describing the interaction between the prominence of safety cues and consumers’ mindsets, and its influence on risk perceptions and service evaluations. We propose that people with implemental (vs. deliberative) mindset show aversive responses toward prominent (vs. non-prominent) safety cues, and perceive higher level of risk and display unfavorable service evaluations. We collected data from an experiment using an artificial online financial company as a consumption context. To test the proposed hypotheses, we conducted a series of regression analyses, which used participants’ computer efficacy as a control variable, and found the following results. First, we found a significant interaction between consumers’ mindsets and the prominence of safety cues. Consumers with deliberative mindset showed lower preference and higher perceived risk toward the online transaction system with highly prominent safety cues than one with less prominent ones. On the other hand, consumers with implemental mindset showed higher preference and lower perceived risk toward the online transaction system with highly prominent cues than one with less prominent cues. Second, we further found that computer efficacy also interacts with the prominence of safety cues. Consumers with low computer efficacy showed lower preference and higher perceived risk toward the online transaction system with highly prominent safety cues than one with less prominent ones. On the other hand, consumers with high computer efficacy showed higher preference and lower perceived risk toward the online transaction system with highly prominent cues than one with less prominent cues. Finally, the test of mediated moderation revealed that consumers’ perceived uncertainty fully mediate the both interactions (i.e., between consumer mindset and prominence and between computer efficacy and prominence) to service evaluations. While many policy makers and system developers in Korea have emphasized the importance developing secure online financial transaction systems, their interests lies heavily on the technical aspects of financial transaction systems (e.g., the security problems of using Active-X based transaction system) for developing secure programs preventing informational leaks or hackings. Consequently, they have neglected non-technical aspects of the online financial transaction platform, which can also generate a significant amount of psychological uncertainty to online service users. Our study demonstrated that the prominence of safety cue (a non-technical characteristics of the system) produce different amounts of uncertainty among consumers, and influence service evaluations. These findings suggest that marketers recognize and understand psychological forces related to consumers’ perceptions on online security programs, and reflect the effect of such non-technical aspects in developing and implementing online transaction platforms.

TS 1-5 : A double-blind, split-face, randomized study on the effects and safety of intradermal injection of Botulinum toxin A in the cheek

( Dong Min Shin ),( Jongeun Lee ),( Hyungrye Noh ),( Dongwhi Jang ),( Se Jin Oh ),( Ji-hye Park ),( Dongyoun Lee ),( Joo-heung Lee ),( Jong Hee Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.-

Background: Intradermal injection of botulinum toxin A (BTXA) is used for cosmetic purposes without strong evidence for clinical use, as opposed to intramuscular injection. Objectives: To evaluate the efficacy and safety of intradermal injection of BTXA in the cheeks. Methods: We conducted a study with 15 volunteers who received intradermal injection of BTXA into one cheek and normal saline into the contralateral side as a control. Volunteers visited the clinic at weeks 2, 4, 8, and 12 after injection. At each visit, pores and wrinkles were evaluated by a facial analyzer, sebum secretion by a sebumeter, skin texture by both volunteers and clinicians, and wrinkles of the nasolabial fold were graded with photographic reviews. Results: There were no significant effects of BTXA on the wrinkles of the infraorbital area and sebum secretion. However, there were significant improvements in the wrinkles of the nasolabial fold and skin texture on the side injected with BTXA. The effects on the wrinkles of the nasolabial fold lasted 12 weeks, and those on skin texture lasted 8 weeks. Improvement in the size of the pores was observed only at week 2. Conclusion: Intradermal injection of BTXA could provide clinical benefits for skin texture and wrinkles.

Revisited: Clinical benefit of punch elevation in acne scar

( Dong Min Shin ),( Donghwi Jang ),( Jongeun Lee ),( Hyun Jeong Byun ),( Se Jin Oh ),( Hyun Jae Kim ),( Ji-hye Park ),( Jong Hee Lee ),( Dong-youn Lee ),( Joo-heung Lee ),( Jun-mo Yang ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Recently, lasers are most common treatment for acne scars, lasers have side effects like post inflammatory hyperpigmentation or post inflammatory erythema. Lasers are also resistant to boxcar type acne scars or deep scars. Objectives: We revisit the punch elevation for these resistant acne scars. And we want to know how effective the punch elevation is. Methods: We applied 7 patients. We measure the volume of depression of skin with Antera 3D, before and after treatment with punch elevation. Results: 6 patients had already been treated with lasers. But there were limitations to treatment. We measure the total volume of the depression of the punch sites. After 1 month, depression volume decreased from 23.6% to 66.7%. Two patients measured volume after 1month, and showed further decrease in volume. Conclusion: Lasers are most common treatment for acne scars and effective treatment. But they also have limitations and side effects. Punch elevation could be a useful treatment for these patients. Because we offered combination therapy with fractional lasers, we can’t know the exact effects of punch elevations. But, considering previous papers and patients’ history of treatment resistance, punch elevation had a significant effect. Our findings revisit the clinical benefits of punch elevations. And it is necessary to establish a treatment modality with punch elevation.

Reuse of industrial sludge waste as a raw material in coagulant production

Eunkyung Lee,Jongeun Shin,Jonghyun Hong 대한환경공학회 2019 대한환경공학회 학술발표논문집 Vol.2019 No.-

Delay in the histopathologic diagnosis of mycosis fungoides

( Dong Min Shin ),( Hyungrye Noh ),( Donghwi Jang ),( Jongeun Lee ),( Se Jin Oh ),( Jong Hee Lee ),( Joo-heung Lee ),( Dongyoun Lee ),( Ji-hye Park ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.72 No.2

A double-blind, split-face, randomized study on the effects and safety of intradermal injection of Botulinum toxin A in the cheek

( Dong Min Shin ),( Jongeun Lee ),( Hyungrye Noh ),( Dongwhi Jang ),( Se Jin Oh ),( Ji-hye Park ),( Dongyoun Lee ),( Joo-heung Lee ),( Jong Hee Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1

Background: Intradermal injection of botulinum toxin A (BTXA) is used for cosmetic purposes without strong evidence for clinical use, as opposed to intramuscular injection. Objectives: To evaluate the efficacy and safety of intradermal injection of BTXA in the cheeks. Methods: We conducted a study with 15 volunteers who received intradermal injection of BTXA into one cheek and normal saline into the contralateral side as a control. Volunteers visited the clinic at weeks 2, 4, 8, and 12 after injection. At each visit, pores and wrinkles were evaluated by a facial analyzer, sebum secretion by a sebumeter, skin texture by both volunteers and clinicians, and wrinkles of the nasolabial fold were graded with photographic reviews. Results: There were no significant effects of BTXA on the wrinkles of the infraorbital area and sebum secretion. However, there were significant improvements in the wrinkles of the nasolabial fold and skin texture on the side injected with BTXA. The effects on the wrinkles of the nasolabial fold lasted 12 weeks, and those on skin texture lasted 8 weeks. Improvement in the size of the pores was observed only at week 2. Conclusion: Intradermal injection of BTXA could provide clinical benefits for skin texture and wrinkles.