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      • Application of Artificial Insemination Technology for Dairy Breeding in Mongolia

        Hyun‐Tae Jo,Jong‐In Jin,Seong‐Su Kim,Byung‐Hyun Choi,Tumor Baldan,Jung‐Gyu Lee,Yun‐Shik Kim,Sam‐Churl Kim,Il‐Keun Kong 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

        This study was focused on improvement of milk production in Mongolia dairy industry by artificial insemination (AI) technology, of which was supported from ODA project of KOICA in Republic of Korea. The study was started from January 2009 to present and 3rd years in this year. So, all data, especially synchronization and pregnancy of dairy cows (Holstein) will be summarized in final result in this year. For synchronization, total 81 dairy cows selected from 4 private farms that were 38, 30, 8 and 5 in Undarmal milk, Onjin (Enkhbayer), Jargalant, and BRM School, respectively. All the dairy cows were injected intramuscular (IM) of 5 ml PGF2α in the vulva and detected estrus 2 to 3 days after PGF2α injection. Total 78 out of 81 dairy cows (96.3%) were detected estrus by only 1 time injection of PGF2α. The dairy cows that were induced estrus, inseminated with 0.5 ml dairy frozen semen by conventional AI techniques. The pregnancy diagnosis of the AI dairy cows was detected by uterus palpation after 60 days of insemination. Total 75 from 78 inseminated dairy cows (90.1%) were diagnosis pregnant. The estrus induction and pregnant rate were very effective using PGF2α injection and conventional AI techniques in Mongolia dairy cow. The results indicated that AI after estrus induction in Mongolia dairy cows could be applied to dairy breeding technology to improve the breeding efficiency and milk production.

      • 紅花가 高Cholesterol 食餌에 의한 家兎의 高脂血病에 미치는 影響

        鄭承鉉,朴性植,李源哲 동국대학교 경주대학 1995 東國論集 Vol.14 No.-

        In order to evaluate the effects of Carthami Flos on the Hyperlipidemia induced by high cholesterol diet, rabbit were fed with 4% cholesterol diet, 4% cholesterol - Carthami Flos diet (2g/㎏/day) during 12weeks. After 12 weeks, serum lipid levels of rabbits were studied. The results were obtained as followed ; Carthami Flos Group had a decrease effect of serum total cholesterol, triglyceride, total lipid, free fatty acid and LDL-cholesterol level. Whereas Carthami Flos Group had a decrease tendency effect of serum phospholipid level and a increase tendency effect of serum HDL-cholesterol level but P-value did not show a significance.

      • 홍국균의 최적배양조건에 관한 연구

        정순택,임종환,박양균,황금택,박현진,안찬영,강성국,문길만 木浦大學校 工業技術硏究所 1994 工業技術硏究誌 Vol.4 No.-

        Cell growth and pigment productivity of Monascus anka KCCM 11832 and Monascus sp. has isolated from the Korean Maeju(soybean koji) were determined for effect of culture medium composition and incubation conditions. Increase of NH₄NO₃, and KH₂PO₄ concentration as mineral source promoted mycelium growth, and the highest cell growth was showed in the medium with 0.05% KH₂PO₄ when C/N ratio is 20:1, but pigment production was significantly inhibited at higher concentration than this level. Cell growth and pigment production in porato dextrose medium were higher than those in czapeck-dox broth and malt extract medium. In terms of temperature, the highest cell growth was showed at 34℃, but pigment productivity was the highest at 26℃.

      • 세침 흡인술을 이용한 종창된 림프절의 세포학적 평가

        백강현,윤기영,최호정,정성목,이영원,조성환,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

        Fine needle aspiration(FNA) cytology is considered as the diagnostic technique of choice in the assessment of swellen lymph nodes. The aim of this study is to determine the indication and diagnostic method of FNA of lymph node lesions performed at Veterinary Medicine Teaching Hospital of Chungnam National University. The records of 16 patients which had undergone FNA during the study period were retrieved. The cytological results were classified as lymphadenitis, lymphoid hyperplasia and lymphoma. Lymphoma cases were classified as B-cell origin and T-cell by immunophenotyping. The result of the FNA cytological diagnosis showed that nine (56%) of the patients were lymphoma, five (31%) of the patients were lymphoid hyperplasia and two (13%) of the patients were lymphadenitis.

      • KCI등재후보

        폐렴구균 감염증에서 항생제 내성의 임상적 의미 : Asian Network for Surveillance of Resistant Pathogens(ANSORP) Study

        정숙인,기현균,손준성,고관수,김나영,장현하,오원섭,백경란,이남용,김신우,이혁,--,송재훈 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

        목적 : 전 세계적으로 폐렴구균의 페니실린을 포함한 β-lactam과 마크로라이드 및 퀴놀론 계열의 항생제에 대한 내성이 급격히 증가하여 임상적으로 문제가 되고 있으나, 시험관내 내성이 실제 임상적 예후에 미치는 영향에 대해서는 아직까지 논란이 되고 있다. 본 연구는 폐렴구균의 항생제 내성률이 높은 아시아 지역에서 항생제 내성이 폐렴구균 감염증의 임상경과에 미치는 영향을 평가하기 위하여 시행되었다. 방법 : ANSORP에서 주관한 전향적 임상 연구로서 1999년 11월부터 2001년 8월까지 아시아 지역 11개국의 14개 기관에서 진단된 침습성 폐럼구균 감염증 환자를 대상으로 내성 균주 감염의 위험요인, 임상양상, 예후 등의 임상적 분석을 시행하였다. 결과 : 총 646명 환자의 평균연령은 30.1세(6일-89세)였고, 이전 3개월 내에 항생제 사용력이 있는 환자는 159명(32.4%)이었다. 질환별로는 폐렴이 377예(58.4%)로 가장 많았고, 중이염 67예, 뇌수막염 66예(10.2%), 일차성 균혈증 65예(10.1%)였다. 총 646균주 중 347균주(53.7%)가 페니실린 비감수성(중등도 내성 23.1%, 고도 내성 23.1%)이었고, 페니실린에 대한 MIC_(90)은 0.03㎍/mL에서 4㎍/mL까지의 분포를 보였다. 페니실린 비감수성 균주에 의한 감염증과 차이가 없었다. 페니실린 내성 폐렴구균 폐렴에 의한 사망률은 페니실린 감수성 폐렴구균 폐렴에 의한 사망률과 차이가 없었다(p=0.846). Erythromycin에 대한 고도 내성을 보이는 균주의 비율이 매우 높았으나, 실제 임상상이나 치사율에는 영향을 미치지 않았다(p=0.092). 페니실린 비감수성 폐렴구균에 의한 뇌수막염의 치사률도 감수성 균주에 의한 사망률과 차이가 없었다(p=0.059). 결론 : 본 연구의 결과 페니실린 및 베타 락탐 제제에 대한 시험관 내성은 폐렴구균 폐렴이나 뇌수막염의 임상상이나 치사율에 영향을 미치지 않는 것으로 확인되었다. 이는 내성의 정도와 연관될 것으로 생각되므로, 향후 고도 내성 균주가 증가할 때 추가 검증을 요한다. 아울러 macrolide 및 퀴놀론계 항생제 내성의 임상적 의미에 대한 후속 연구가 필요할 것으로 사료된다. Background : Despite the widespread emergence of antimicrobial resistance among pneumococcal strains worldwide, clinical implications of in vitro resistance still remain an open question. To evaluate the clinical impact of pneumococcal resistance in Asian countries where the prevalence of pneumococcal resistance was reported to be highest in the world, ANSORP has performed a prospective, multinational surveillance study with cases with invasive pneumococcal diseases in Asian countries. Methods : In vitro susceptibility of pneumococcal isolates was determined by broth microdilution tests with 16 antimicrobial agents. All enrolled cases of pneumococcal infections were analyzed with regard to demographic data, clinical features, risk factors and mortality. Results : A total of 646 patients with pneumococcal infections were enrolled from 14 centers in 12 countries between the period from November 1999 to August 2001. Pneumonia (58.4%) was the most common clinical disease followed by bacteremia (33.4%), otitis media (10.4%), and meningitis (10.2%). Among 646 isolates, 347 (53.7%) were penicillin non-susceptible (intermediate 23.1%, resistant 30.7%). MIG_(90)s for penicillin ranged from 0.03 (India) to 4.0 ㎍/mL (Korea, Taiwan, Vietnam, and Hong Kong). Overall mortality from pneumococcal diseases by penicillin non-susceptible strains was not different from that by susceptible strains. Pneumococcal pneumonia caused by penicillin- or erythromycin-resistant strains showed similar mortality, severity of illness, or complications to that by susceptible strains. Mortality from pneumococcal meningitis caused by penicillin non-susceptible strains was also similar to that by susceptible strains. Conclusion : Data suggest that current situation of in vitro resistance to penicillin or macrolides may not affect the mortality from pneumococal pneumonia or meningitis caused by antibiotic-resistant strains.

      • 개 비장 질환의 미세세침흡입술을 통한 세포병리학 검사 4례

        김현아,윤기영,최호정,정성목,이영원,조성환,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

        To evaluate the accuracy and diagnostic significance of cytopathological diagnosis of canine splenic disorders, cytopathological examination throgh fine-needle aspiration(FNA) referred to Veterinary Medical Teaching Hospital of Chungnam National University were retrospectived. Splenic neoplasm, hemolymphatic neoplasm, hyperplasia, extramedullary hematopoiesis and splenitis were diagnosed canine splenic disorders through cytopathological examination. The patient should be identified what coagulation profile are normal before aspiration, because complication such as hemorrhage could happen. The 4 cases were identified symmetric, asymmetric splenomegaly on abdominal ultrasonography and then were performed ultrasound-guided FNA. The 4 cases were diagnosed hemangiosarcoma(2), hyperplasia(1) and extramedullary hematopoiesis(1) by clinical signs, hematological examination, and cytopathological examination. Cytopathological examination through FNA was cost-effective, no gneral anesthesia, no complication, and non-invasive method of diagnosis for canine splenic disorders.

      • KCI등재

        골격성 Ⅲ급 부정교합자에서 상악골 전진술을 동반한 양악 수술 시 중안면 연조직 형태의 변화

        정종현,김성식,손우성,박수병 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.2

        본 연구는 중안면 함몰이 있는 골격성 III급 부정교합자의 중안면의 형태를 정상 표본과 비교하고, 악교정수술에 의하여 연조직이 어떤 변화를 보이는지를 알아보기 위하여 시행하였다. 골격성 III급 부정교합으로 진단받고 상악 전진술과 하악 후퇴술을 시행받은 환자 34명 (남자:15명, 여자:19명)을 대상으로 수술 전후 측모 두부방사선 계측사진을 분석하였다. 골격성 III급 부정교합자의 중안면의 경조직 계측치 S'-Or, Or⊥NA, S'Or/SN, ∠SNOr에서 남녀 모두에서 정상 교합자와 큰 차이가 있었다. 상악골이 평균 5.03 mm 전방이동 될 때 연조직 Orbitale는 2.26 mm 전방으로 이동하였으며 상관계수는 0.599였다(p < 0.05). 상악 평면각의 변화(시계방향으로 회전)와 상악골의 수직 이동은 연조직 Orbitale의 전방이동과 유의성있는 상관관계가 없었다. 상악골 전방이동에 대한 연조직 Orbitale와 Subnasale의 전방이동 비율은 각각 43.57%, 81.54%였다. 이상의 결과에서 중안면 함몰이 있는 환자는 상악골 전방이동시 상순과 비부 외에도 연조직 Orbitale를 포함한 중안면 연조직이 전방으로 이동하지만, 상악골의 회전이동 및 수직이동에 대해서는 연조직의 변화량이 적었다는 것을 알 수 있었다. 이는 상악골의 수술에 따른 중안면 함몰의 해소를 예측하는 데 도움이 될 것이다. Purpose: The first objective of this study was to compare the upper midface morpholgy, focusing on the soft tissues, between skeletal Class III maloccusion patients with midfacial depression and the norm. The second objective was to estimate and analyze the change in the upper midface soft tissues following surgical correction with maxillary advancement by Lefort I osteotomy and mandibular setback by bilateral sagittal split osteotomy (BSSRO). Methods: The samples consisted of 34 adult patients (15 males and 12 females) with an average age of 21 years, who had severe anteroposterior discrepancy with midfacial depression. These patients had received presurgical orthodontic treatment and surgical treatment which consisted of simultaneous Lefort I osteotomy and BSSRO. Results: The correlation coefficient between changes in maxillary advancement and changes in Or' (soft tissue orbitale) was 0.599 (P < 0.05). Change in maxillary plane angle and vertical change of the maxilla were not correlated with the change in Or' (P < 0.05). The ratio of soft tissue change in Or' to maxillary advancement was 43.57 %, and 81.54 % in Sn. Regression equations between maxillary movement and Or' were devised. The r² value was 0.476. Conclusions: The majority of measurements in the upper midface in skeletal Class III maloccusions when compared to the norm, showed significant differences. In Class III malocclusion with midfacial depression, maxillary advancement produces soft tissue change in the upper midface.

      • 베체트병에서 만성 기침으로 발현한 폐동맥류 1예

        정승현,송주경,정성수,강성욱 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

        저자들은 만성 기침이 있었으나 정확한 원인을 찾지 못한 채 보존적 치료만 받던 베체트병이 있는 37세 여자환자를 경험하였고 흉부 방사선사진과 흉부 전산화 단층 촬영으로 폐동맥류로 진단하고 고용량의 스테로이드로 치료하였고 이 과정에서 대량 객혈이 있었으나 보존적 치료로 호전된 베체트병 1 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Pulmonary Artery Aneurysm Manifesting as Chronic cough in Behcet's disease Behcet's disease is a relapsing chronic inflammation disorder of unknown etiology. Although Behcet's disease has originally been described as a triad of recurrent oral aphthous ulceration, genital ulceration and uveitis, it is now recognized as a multisystem disease with vasculitis as the main pathological finding. Clinical manifestations additional to this triad include involvement of the skin, joints, large vessels, lung, gastrointestinal and genitourinary tracts, brain. We report a case of pulmonary artery aneurysm manifesting as chronic cough in Behcet's disease. She was a 47 year-old woman with Bechet's disease treated with prednisolone and colchicine. She had suffered from chronic cough for several years, but been treated only with antitussive agents. Chest CT revealed multifocal patchy consolidation in lung parenchym and aneurysmal dialatation of pulmonary artery. We diagnosed pulmonary aneurysm with CT finding as the cause of chronic cough.

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