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- 저자 : Hayashia, Akio (검색결과 2 건)
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Anacardic Acids and Ferric Ion Chelation
Tsujimoto, Kazuo,Hayashia, Akio,Ha, Tae Joung,Kubo, Isao Verlag der Zeitschrift fuer Naturforschung 2007 Zeitschrift fur Naturforschung. Section C Vol.62 No.9
<P>6-Pentadeca(e)nylsalicylic acids isolated from the cashew Anacardium occidentale L. (Anacardiaceae), commonly known as anacardic acids, inhibited the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, type 1) competitively without prooxidant effects. Their parent compound, salicylic acid, did not have this inhibitory activity up to 800 μm, indicating that the pentadeca(e)nyl group is an essential element to elicit the activity. The inhibition is attributed to its ability to chelate iron in the enzyme. Thus, anacardic acids chelate iron in the active site of the enzyme and then the hydrophobic tail portion slowly begins to interact with the hydrophobic domain close to the active site. Formation of the anacardic acids-ferric ion complex was detected in the ratio of 2:1 as the base peak in the negative ion electrospray ionization mass spectrometry. Hence, anacardic acids inhibit both Eox and Ered forms.</P>
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An alternative approach for planning the resilient cities in developing countries
Sameer Deshkar,Yoshitsugu Hayashia,Yasuhiro Mori 서울시립대학교 도시과학연구원 2011 도시과학국제저널 Vol.15 No.1
Twenty-first century cities in developing countries have been facing development challenges as a result of their fast-growing urban populations and inefficient infrastructures, as well as growing difficulties created by climate change. Though concern for integrating disaster risk management approaches into development planning has been expressed in various policy documents and studies, exact methods of such integration at the spatial level are still being deliberated. The concepts of quality of life (QoL) and disaster resiliency are closely linked and their interrelationship is understood from the definitions and concepts developed in different studies. A disaster can have a negative impact on QoL and resiliency for disaster can protect and maintain QoL. This study develops an approach for integrating disaster resiliency into QoL based on new urbanization models, which can be re-orientated towards achieving resiliency. The Quality of Life with Disaster Resiliency (QoLDR) index offers the integration of resiliency issues arising from the urbanization process as well as natural hazards. It also provides directions for altering urbanization and increases adaptability, which results in resilient urbanization.
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