Catalysis Reaction Engineering, Industrial Chemistry : Transformation of Methanol to Gasoline Range Hydrocarbons Using HZSM-5 Catalysts Impregnated with Copper Oxide

( Hasan Akhtar Zaidi ),( Kamal Kishore Pant ) 한국화학공학회 2005 Korean Journal of Chemical Engineering Vol.22 No.3

Combined experimental and kinetic modeling studies for the conversion of gasoline range hydrocarbons from methanol over modified HZSM-5 catalyst

Hasan Akhtar Zaidi,Kamal Kishore Pant 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.5

The reaction was carried out in fixed bed reactor. The effect of process variables on the activity of oxalic acid treated 0.5 wt% ZnO/7 wt% CuO/HZSM5 catalyst for the conversion of methanol to gasoline range hydrocarbons was studied. The catalyst was prepared by incipient wetness impregnation method. After impregnation the catalyst was treated with oxalic acid. The validity of kinetic model proposed for the methanol to gasoline range hydrocarbon process at zero time on stream was studied, from the experimental results obtained in a wide range of operating conditions. The kinetic parameters for various models were calculated by solving the equation of mass conservation in the reactor for the lumps of the kinetic models. The kinetic model fitted well for simulating the operation in the fixed bed reactor in the range of 635 to 673 K,with regression coefficient (R2) higher than 0.96.

Saudi Experts Consensus on Diagnosis and Management of Pediatric Functional Constipation

Dhafer B. Alshehri,Haifa Hasan Sindi,Ibrahim Mohamod AlMusalami,Ibrahim Hosamuddin Rozi,Mohamed Shagrani,Naglaa M. Kamal,Najat Saeid Alahmadi,Samia Saud Alfuraikh,Yvan Vandenplas 대한소아소화기영양학회 2022 Pediatric gastroenterology, hepatology & nutrition Vol.25 No.3

Although functional gastrointestinal disorders (FGIDs) are very common in pediatric patients, there is a scarcity of published epidemiologic data, characteristics, and management patterns from Saudi Arabia, which is the 2nd largest Arabic country in terms of area and the 6th largest Arabic country in terms of population, with 10% of its population aged <5 years. Functional constipation (FC) is an FGID that has shown a rising prevalence among Saudi infants and children in the last few years, which urges us to update our clinical practices. Nine pediatric consultants attended two advisory board meetings to discuss and address current challenges, provide solutions, and reach a Saudi national consensus for the management of pediatric constipation. The pediatric consultants agreed that pediatricians should pay attention to any alarming signs (red flags) found during history taking or physical examinations. They also agreed that the Rome IV criteria are the gold standard for the diagnosis of pediatric FC. Different therapeutic options are available for pediatric patients with FC. Dietary treatment is recommended for infants with constipation for up to six months of age. When non-pharmacological interventions fail to improve FC symptoms, pharmacological treatment with laxatives is indicated. First, the treatment is aimed at disimpaction to remove fecal masses. This is achieved by administering a high dose of oral polyethylene glycol (PEG) or lactulose for a few days. Subsequently, maintenance therapy with PEG should be initiated to prevent the re-accumulation of feces. In addition to PEG, several other options may be used, such as Mg-rich formulas or stimulant laxatives. However, rectal enemas and suppositories are usually reserved for cases that require acute pain relief. In contrast, infant formulas that contain prebiotics or probiotics have not been shown to be effective in infant constipation, while the use of partially hydrolyzed formula is inconclusive. These clinical practice recommendations are intended to be adopted by pediatricians and primary care physicians across Saudi Arabia.

Interaction of Glucagon G-Protein Coupled Receptor with Known Natural Antidiabetic Compounds: Multiscoring <i>In Silico</i> Approach

Baig, M. H.,Ahmad, K.,Hasan, Q.,Khan, M. K. A.,Rao, N. S.,Kamal, M. A.,Choi, I. Hindawi Publishing Corporation 2015 Evidence-based Complementary and Alternative Medic Vol.2015 No.-

<P>Glucagon receptor (GCGR) is a secretin-like (class B) family of G-protein coupled receptors (GPCRs) in humans that plays an important role in elevating the glucose concentration in blood and has thus become one of the promising therapeutic targets for treatment of type 2 diabetes mellitus. GCGR based inhibitors for the treatment of type 2 diabetes are either glucagon neutralizers or small molecular antagonists. Management of diabetes without any side effects is still a challenge to the medical system, and the search for a new and effective natural GCGR antagonist is an important area for the treatment of type 2 diabetes. In the present study, a number of natural compounds containing antidiabetic properties were selected from the literature and their binding potential against GCGR was determined using molecular docking and other<I> in silico</I> approaches. Among all selected natural compounds, curcumin was found to be the most effective compound against GCGR followed by amorfrutin 1 and 4-hydroxyderricin. These compounds were rescored to confirm the accuracy of binding using another scoring function (<I>x</I>-score). The final conclusions were drawn based on the results obtained from the GOLD and <I>x</I>-score. Further experiments were conducted to identify the atomic level interactions of selected compounds with GCGR.</P>

Quality of Life and Psychological Well-Being of Colorectal Cancer Survivors in Jordan

Abu-Helalah, Munir Ahmad,Alshraideh, Hussam Ahmad,Al-Hanaqta, Motasem Mohammad,Arqoub, Kamal Hasan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

Background: Colorectal ranked first among cancers reported in males and ranked second amongst females in Jordan, accounting for 12.7% and 10.5% of cancers in males and females, respectively. Colorectal cancer patients can suffer several consequences after treatment that include pain and fatigue, constipation, stoma complications, sexual problems, appearance and body-image concerns as well as psychological dysfunction. There is no published quantitative data on the health-related quality of life and psychological wellbeing of Jordanian colorectal cancer survivors. Method: This project was a cross-sectional study of colorectal cancer survivors diagnosed in 2009 and 2010. Assessment was performed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the colorectal cancer specific module (EORTC QLQ-CR 29) and the Hospital Anxiety and Depression Scale (HADS). Data on potential predictors of scores were also collected. Results: A total of 241 subjects completed the study with mean age of $56.7{\pm}13.6$. Males represented 52.3% of study participants. A majority of participants reported good to high overall health; the mean Global health score was $79.74{\pm}23.31$ with only 6.64% of study participants scoring less than 33.3%. The striking result in this study was that none of the study participants participated in a psychosocial support group; only 4 of them (1.7%) were even offered such support. The mean scores for HADS, depression score, and anxiety score were $8.25{\pm}9$, $4.35{\pm}4.9$ and $3.9{\pm}4.6$, respectively. However, 77.1% of study participants were within the normal category for the depression score and 81.7% were within this category for anxiety score; 5.4% of participants had severe anxiety and 5.4% of them had severe depression. Discussion: Patients with colorectal cancer in Jordan have a good quality of life and psychological wellbeing scores when compared with patients from western countries. None of the colorectal cancer patients managed at the Ministry of Health received any formal counselling, or participated in psychological or social support programmes. This highlights the urgent need for a psychosocial support programme, psychological screening and consultations for patients diagnosed with colorectal cancer at the Ministry of Health Hospitals.

Experimental and numerical investigation of reinforced concrete beams containing vertical openings

Jafarali Parol,Ammar Ben-Nakhi,Shaikha Al-Sanad,Jamal Al-Qazweeni,Hamad J. Al-Duaij,Hasan Kamal 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.72 No.3

Horizontal openings in reinforced concrete (RC) beams are quite often used to accommodate service pipelines. Several research papers are available in the literature describing their effect. RC beams with vertical openings are commonly used to accommodate service lines in residential buildings in Kuwait. However, there are lack of design guidelines and best practices reported in the literature for RC beams with vertical openings, whereas the detailed guidelines are available for beams with horizontal openings. In the present paper, laboratory experiments are conducted on nine RC beams with and without vertical openings. Parametric study has been carried out using nonlinear finite element analysis (FEA) with changes in the diameter of the opening, various positions of the opening along the length and width of the beam, edge distance, etc. 50 finite element simulations were conducted. The FEA results are verified using the results from the laboratory experiments. The study showed that the load carrying capacity of the beam is reduced by 20% for the RC beam with vertical openings placed near the center of the beam compared to a solid beam without an opening. Significant reduction in load carrying capacity is observed for beams with an opening near the support (≈15%). The overall stiffness of the beam, crack pattern and failure modes were not affected due to the presence of the vertical opening. Furthermore, an artificial neural network (ANN) analysis is carried out using the FEA generated data. The results and observations from the ANN and FEA are in good agreement with experimental results.