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        Testicular Biopsy Histopathology as an Indicator of Successful Restoration of Spermatogenesis after Varicocelectomy in Non-obstructive Azoospermia

        Hamdy Abdelmawla Aboutaleb,Eid Abdel-Rasoul Elsherif,Mohammed Kamal Omar,Tarek Mohammed Abdelbaky 대한남성과학회 2014 The World Journal of Men's Health Vol.32 No.1

        Purpose: We aimed to evaluate the efficacy of using testicular biopsy histopathology as an indicator of the success of loupe-assisted subinguinal varicocelectomy in non-obstructive azoospermia (NOA) patients.Materials and Methods: In a 2-year period, a prospective study was carried at Minoufiya University Hospital on 20 NOA patients with clinical bilateral varicoceles. These patients underwent loupe-assisted subinguinal varicocelectomy with simultaneous testicular biopsy. All patients were evaluated by determining their hormonal profile and performing semen analyses and scrotal Doppler and transrectal ultrasonography. Two semen analyses showing azoospermia were performed before the surgery and two semen analyses were received at 3 and 6 months post-operatively for follow-up.Results: The mean age was 29.9±6.7 years, and the mean follow-up duration was 17.3±8.3 months. We noted the restoration of spermatogenesis in six men (30% of all patients). Testicular biopsy results were as follows: hypospermatogenesis in 7 patients, maturation arrest in 3, and Sertoli cell-only syndrome in 10. The improvement in the sperm counts of these patients ranged from 3 million to 15 million/mL. Sperms were recovered in the hypospermatogenesis (6 patients, 85.5%) patients only, but other patients with testicular biopsy results of Sertoli cell-only or maturation arrest did not show any improvement in their semen parameters. Conclusions: Testicular biopsy results showed that hypospermatogenesis patients have a better chance of improvement in their semen analysis after varicocelectomy in contrast to NOA patients with Sertoli cell-only syndrome or maturation arrest.

      • KCI등재

        Reconstruction of an Amputated Glans Penis With a Buccal Mucosal Graft: Case Report of a Novel Technique

        Hamdy Aboutaleb 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.12

        Penile amputation is a rare catastrophe and a serious complication of circumcision. Reconstruction of the glans penis may be indicated following amputation. Our reportdiscusses a novel technique for reconfiguration of an amputated glans penis 1 year aftera complicated circumcision. A 2-year-old male infant presented to us with glans penisamputation that had occurred during circumcision 1 year previously. The parents complainedof severe meatal stenosis with disfigurement of the penis. Penis length was 3cm. Complete penile degloving was performed. The distal part of the remaining peniswas prepared by removing fibrous tissue. A buccal mucosal graft was applied to thedistal part of the penis associated with meatotomy. The use of a buccal mucosal graftis a successful and simple procedure with acceptable cosmetic and functional resultsfor late reconfiguration of the glans penis after amputation when penile size is suitable.

      • KCI등재

        Anuria in a 9-Month-Old Infant Resulting from Ureteral Cystine Stones

        Hamdy Aboutaleb 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.9

        Pediatric urolithiasis and calcular anuria in early infancy are rare. Cystine stones may develop in utero or during early infancy. We report the case of a female 9-month-old infant with obstructive anuria resulting from cystine stones in a single functioning unit. She presented to the emergency department owing to the absence of micturition for 3 days. Radiological investigations revealed four left ureteral stones and an atrophic right kidney resulting from a calcular obstruction. Her laboratory values were as follows: serum creatinine 6.7 mg/dl, Na 132 mEq/l, K 6 mg/dl, and hematocrit 32%. An urgent percutaneous nephrostomy tube was inserted into the left side for urinary drainage, and her serum levels of creatinine and K returned to normal within 3 days. A left ureterolithotomy was the final management. Stone analysis revealed pure cystine crystals.

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