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        Nitrogen doped waste tea residue derived carbon dots for selective quantification of tetracycline in urine and pharmaceutical samples and yeast cell imaging application

        Gunjal, Datta B.,Gurav, Yogesh M.,Gore, Anil H.,Naik, Vaibhav M.,Waghmare, Ravindra D.,Patil, Chandrashekhar S.,Sohn, Daewon,Anbhule, Prashant V.,Shejwal, Rajendra V.,Kolekar, Govind B. North-Holland 2019 Optical materials Vol.98 No.-

        <P><B>Abstract</B></P> <P>In this work, waste tea residue, abundantly accessible, is utilized for synthesis of fluorescent carbon dots (CDs) by a simple, low cost and one step chemical oxidation method. The optical properties, surface functionality and particle size of CDs were ascertained by various techniques. The CDs exhibited excellent water solubility, optical properties, bioimaging ability etc. The fluorescence intensity of the CDs was diminished gradually with increasing concentrations of tetracycline drug owing to the inner filter effect (IFE) phenomenon. The developed fluorescent probe displayed a better linear range, excellent detection limit and interference free response to the tetracycline. This resulted in quantification of tetracycline in real sample which achieved almost 99% recoveries indicated excellent practical potential. Moreover, the CDs were used as fluorescent label for multicolour imaging of yeast cells which could open the doors for further research in biological fields.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Carbon Dots derived from waste tea residue by simple reflux method. </LI> <LI> Determination of Tetracycline by fluorescence quenching through inner filter mechanism. </LI> <LI> Simple, sensitive and interference free method. </LI> <LI> Carbon dots as a fluorescent label for multicolour cell imaging. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Schematic of synthesis of CDs and inner filter effect based detection of tetracycline.</P> <P>[DISPLAY OMISSION]</P>

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        Effect of Dental Practicality Index training using an online video on decision-making and confidence level in treatment planning by dental undergraduates

        See Zhai Wei,Lee Ming Sern,Parolia Abhishek,Kanagasingam Shalini,Gunjal Shilpa,Patel Shanon 대한치과보존학회 2024 Restorative Dentistry & Endodontics Vol.49 No.1

        Objectives The purpose of this study was to evaluate the effect of Dental Practicality Index (DPI) training using an online video on the treatment planning decisions and confidence level of dental undergraduates (DUs). Materials and Methods Ninety-four DUs were shown 15 clinical case scenarios and asked to decide on treatment plans based on 4 treatment options. The most appropriate treatment plan had been decided by a consensus panel of experienced dentists. DUs then underwent DPI training using an online video. In a post-DPI-training test, DUs were shown the same clinical case scenarios and asked to assign the best treatment option. After 6 weeks, DUs were retested to assess their knowledge retention. In all 3 tests, DUs completed the confidence level scale questionnaire. Data were analyzed using the related-samples Wilcoxon signed rank test and the independent-samples Mann-Whitney U test with the level of significance set at p < 0.05. Results DPI training significantly improved the mean scores of the DUs from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training. Conclusions Training DUs using DPI with an online video improved their decision-making and confidence level in treatment planning. Objectives The purpose of this study was to evaluate the effect of Dental Practicality Index (DPI) training using an online video on the treatment planning decisions and confidence level of dental undergraduates (DUs). Materials and Methods Ninety-four DUs were shown 15 clinical case scenarios and asked to decide on treatment plans based on 4 treatment options. The most appropriate treatment plan had been decided by a consensus panel of experienced dentists. DUs then underwent DPI training using an online video. In a post-DPI-training test, DUs were shown the same clinical case scenarios and asked to assign the best treatment option. After 6 weeks, DUs were retested to assess their knowledge retention. In all 3 tests, DUs completed the confidence level scale questionnaire. Data were analyzed using the related-samples Wilcoxon signed rank test and the independent-samples Mann-Whitney U test with the level of significance set at p < 0.05. Results DPI training significantly improved the mean scores of the DUs from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training. Conclusions Training DUs using DPI with an online video improved their decision-making and confidence level in treatment planning.

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