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Guang Kui Zhou,Xiao Dong Zhi,Deng Ming Pan,Tim Hsu,Jen-taut Yeh 한국고분자학회 2022 Macromolecular Research Vol.30 No.2
Quaternary ammonium salt modified montmorillonite (QASMMT) nanoplatelets were well dispersed in poly(ether ketone ketone) (PEKK) polymers to make pleasing fifth generation (5G) substrates. Substantially smaller dielectric properties and linear thermal expansion coefficient (LCTE) were found for each PEKKa xQASMMTy film series filled with small and appropriate QASMMT loadings. The dielectric constant (εr) and dielectric loss (tan δ) values acquired for each PEKKa xQASMMTy film series reduced to a lowest value as QASMMT loadings approached 3wt%. Satisfactory εr (2.59, 2.71, and 2.80 at 1 MHz), tan δ (0.0032, 0.0038, and 0.0042 at 1 MHz) and LCTE (~36.8×10-6/℃, 38.8×10-6/℃ and 40.5×10-6/℃) for 5G communication were acquired for PEKKa 97QASMMT3 films filled with only 3wt% optimum loading of QASMMT nano-platelets. In the meantime, the onset degradation temperatures acquired for each PEKKa xQASMMTy film series increased substantially with increasing QASMMT loadings. All free volume properties, such as, the radius of the free-volume-cavity or free-volume-cavity numbers per unit volume evaluated for every PEKKa xQASMMTy film sequence enlarged to a largest value, as QASMMT loadings approached an appropriate value of 3wt%. Substantial smaller εr and tan δ were acquired for PEKKa and PEKKa xQASMMTy with larger free volume properties. Possible reasons accounting for these substantially diminished dielectric and LCTE properties of PEKKa xQASMMTy films are proposed.
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Inhibition of SMP30 Gene Expression Influences the Biological Characteristics of Human Hep G2 Cells
Zhang, Sheng-Chang,Liang, Ming-Kang,Huang, Guang-Lin,Jiang, Kui,Zhou, Su-Fang,Zhao, Shuang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3
Senescence marker protein 30 (SMP30), a hepatocellular carcinoma (HCe) associated antigen had been identified by our research group. To study its mechanisms of regulation and associations with the occurrence and development of HCe, we inhibited expression by RNAi technique, and observed effects on the biological characteristics of Hep G2 cells. In cell viability assays, cell growth in the experimental group (with siRNA transfection) was elevated. In Transwell invasion assays, compared with blank and control groups, numbers of invading cells in the experimental group were significantly increased, whereas in apoptosis assays, the percentage apoptosis demonstrated no differences, but after UV irradiation, that in the experimental group was higher than the other two groups. In a word, SMP30 can inhibit the proliferation and invasion of human hepatoma cells and thus can be regarded as a cancer suppressive factor.
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