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      • KCI등재

        Non-Exposure Endoscopic-Laparoscopic Cooperative Surgery for Stomach Tumors: First Experience from the Czech Republic

        Jan Hajer,Lukáš Havlůj,Adam Whitley,Robert Gürlich 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.2

        Background/Aims: The aim of this study was to investigate the use of non-exposure endoscopic wall-inversion surgery (NEWS) andthe combination of laparoscopic and endoscopic approaches to neoplasia with non-exposure technique (CLEAN-NET) in gastrictumors. Methods: We reviewed all cases of NEWS and CLEAN-NET performed in the department of surgery of the Royal VinohradyTeaching Hospital. Results: Our department performed 12 gastric tumor resections (NEWS, n=10 and CLEAN-NET, n=2) between March 2016 andFebruary 2017. The cases chosen for these resections included predominantly submucosal tumors with no signs of dissemination orlocal invasion and early gastric carcinomas (T1SM1 and T1M), where tumor location made it impossible to use endoscopic submucosaldissection. R0 resection margins were confirmed in all the cases. Conclusions: NEWS and CLEAN-NET allow en bloc non-exposed full-thickness gastric wall resection in a way that uses a “close first,cut later” approach to prevent seeding of the peritoneal cavity with tumor cells. These mini-invasive techniques combine laparoscopicand endoscopic techniques, and preserve the full function of the stomach.

      • KCI등재

        Polarization-dependent Photore Quantum Well Structure

        G. J. Jan,C. M. Lai,J. H. Huang 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.42 No.III

        We have measured the polarization-dependent photore ectance spectra of InGaP/GaAs quantum well structure. These quantum well specimens were grown by gas source molecular beam epitaxy at the growth temperature 440 C, 480 C and 520 C for C1007, C1008 and C1009, respectively. Each of these samples consists of a 7 nm GaAs well, 0.2 m (top) and 1 m (bottom) InGaP barrier. The properties of InGaP layer were obtained by characterized the InGaP/GaAs epilayer sample using double X-ray diraction and low temperature photoluminescence experiments. The results show that the strains of InGaP for all samples are less than 0.2 % and the ordered parameters are about 0.3. The PR spectra demonstrate the anisotropic optical properties. Besides, the energy dierences between the ground states are almost equal to the dierences between bandgap of the InGaP barrier. And the ground state energy is 4 meV less than GaAs bandgap for sample C1009. These results suggest that the transitions of QW structure strongly involve with the partial ordered InGaP barrier by type II band alignment.??

      • KCI등재

        Photoluminescence of InGaAsN/GaAs Single Quantum Well Grown by Metal-organic Chemical Vapor Deposition

        G. J. Jan,B. R. Wu,C. M. Lai,J. H. Huang,Y. L. Yang 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.42 No.III

        We report the measured results of the temperature dependent photoluminescence (PL) spectra of In$_{0.3}$Ga$_{0.7}$As/GaAs and In$_{0.3}$Ga$_{0.7}$As$_{0.998}$N$_{0.002}$/GaAs single quantum well (SQW) grown by metal-organic chemical vapor deposition (MOCVD). The optical properties of the InGaAs epilayers incorporated with small concentration of nitrogen and two growth temperatures have been investigated. The results show that the optical transition energy on the PL spectra presents the blue shift instead of the red shift raising the growth temperature from 520 $^\circ$C to 550 $^\circ$C with or without nitrogen incorporation. Two (or three) energy features on PL spectrum of InGaAsN SQW grown at growth temperature 520 $^\circ$C were obtained and presumably ascribed to the formation of In-rich clusters. In addition, inverted ``S-curve'' on temperature dependence PL transition energy was observed in InGaAsN SQW grown at 520 $^\circ$C and the carrier localization is interpreted.

      • SCISCIE
      • KCI등재

        What do we know about uncommon complications associated with third molar extractions? A scoping review of case reports and case series

        Naichuan Su(Naichuan Su ),Sana Harroui(Sana Harroui ),Fred Rozema(Fred Rozema ),Stefan Listl(Stefan Listl ),Jan de Lange(Jan de Lange ),Geert J.M.G. van der Heijden(Geert J.M.G. van der Heijden ) 대한구강악안면외과학회 2023 대한구강악안면외과학회지 Vol.49 No.1

        The current study aimed to explore the types and frequencies of uncommon complications associated with third molar extractions based on a scoping review of case reports and case series. The study used an electronic literature search based on PubMed and Embase up to March 31, 2020, with an update performed on October 22, 2021. Any case reports and case series that reported complications associated with third molar extractions were included. The types of complications were grouped and the main symptoms of each type of complication were summarized. A total of 51 types of uncommon complications were identified in 248 patients from 186 studies. Most types of complications were post-operative. In the craniofacial and cervical regions, the most frequent complications included iatrogenic displacement of the molars or root fragments in the craniofacial area, late mandibular fracture, and subcutaneous emphysema. In other regions, the most frequent complications include pneumomediastinum, pneumorrhachis, pneumothorax, and pneumopericardium. Of the patients, 37 patients had life-threatening uncommon complications and 20 patients had long-term/irreversible uncommon complications associated with third molar extractions. In conclusion, a variety of uncommon complications associated with third molar extractions were identified. Most complications occurred in the craniofacial and cervical regions and were mild and transient.

      • KCI등재후보

        Shear-banding instabilities

        Jan K.G. Dhont,Kyongok Kang,M.P.Lettinga,W. J. Briels 한국유변학회 2010 Korea-Australia rheology journal Vol.22 No.4

        Gradient-banding and vorticity-banding instabilities, as well as a shear-induced instability due to shear-gradient induced mass transport will be discussed. Various scenarios that underly these instabilities are addressed and simple constitutive relations that allow for a (semi-) quantitative analysis are proposed. A relatively simple constitutive equation that has been proposed some time ago is reviewed, which captures a number of the experimentally observed gradient-banding phenomena. This constitutive equation is based on the usual formal expansion of the stress tensor with respect to gradients in the flow velocity, but now including the second order term. The second order term is necessary to describe the relatively large spatial gradients within the interface between the two bands. The resulting simple constitutive equation is shown to give rise to stationary gradient-banded states, where the shear rates within the bands are constant, it describes stress selection under controlled rate conditions and explains why banding can not occur under controlled stress conditions. The simple constitutive equation does not include coupling to concentration, which may give rise to banding also under controlled stress conditions. Two examples of mechanisms that lead to the strong shear thinning that is necessary for gradient banding are discussed: (i) transient forces due to entanglements in polymer systems, and (ii) critical slowing down. The latter mechanism is shown to be important for a worm-like micellar system. The mechanism that leads to vorticity banding is still under debate. Vorticity banding of fd-virus suspensions within the two-phase isotropic-nematic coexistence will be discussed. Experiments on the kinetics of banding and particle-tracking experiments lead to a recently proposed mechanism for the vorticity-banding instability, where the instability is identified as an elastic instability similar to the polymer-Weissenberg effect. The role of polymer chains in the classic Weissenberg effect is now played by inhomogeneities formed during the initial stages of phase separation. For other systems than fd-virus suspensions that exhibit vorticity banding, the inhomogeneities general have a different origin, like in weakly aggregated colloids and worm-like micellar systems where the inhomogeneities are the colloidal aggregates and the worms, respectively. An instability that has been discovered some time ago, which is an instability due to shear-gradient induced mass transport is also discussed. The coupling between shear-gradients and mass transport has been formally introduced through a shear-rate dependent chemical potential, of which the microscopic origin was not explained. It will be shown that the microscopic origin of this coupling is related to the shear-induced distortion of the pair-correlation function. Contrary to the stationary gradient-banded and vorticity-banded state, it is not yet known what the stationary state is when this shear-concentration-coupling instability occurs.

      • KCI등재

        Technical Barriers, Import Licenses and Tariffs as Means of Limiting Market Access

        ( Jan G. Jørgensen ),( Philipp J. H. Schroder ) 세종대학교 경제통합연구소 (구 세종대학교 국제경제연구소) 2006 Journal of Economic Integration Vol.21 No.1

        Technical barriers (standards), import licenses and tariffs may be deployed as means of limiting the market access of foreign firms. The present paper examines these measures in a setting of monopolistic competition. We find that, if protection focuses predominantly on the number of foreign firms accessing the domestic market, a technical barrier (an import license) may dominate a tariff (tariff and a technical barrier) in terms of consumer welfare, even when tariff revenues are fully redistributed. However, if protection pays sucfficient focus on limiting the total import volume, then tariffs are the preferred means of protection. Within the model, reductions in technical barriers and tariffs, the removal of licensing schemes, and a harmonization of standards are all welfare-improving policies.

      • Strengthening the Reporting of Observational Studies in Epidemiology(STROBE): 국문판 설명문서

        Jan P. Vandenbroucke,Erik von Elm,Douglas G. Altman,Peter C. Gøtzsche,Cynthia D. Mulrow,Stuart J. Pocock,Charles Poole,James J. Schlesselman,Matthias Egger Ewha Womans University School of Medicine 2024 EMJ (Ewha medical journal) Vol.47 No.2

        의학 연구의 대부분은 관찰 연구이다. 관찰 연구의 보고는 종종 불충분한 품질을 보이기도 한다. 부실한 보고는 연구의 강점과 약점을 평가하고 연구 결과의 일반화 가능성을 평가하는 데 방해가 된다. 방법론 전문가, 연구자, 편집자 그룹은 경험적 근거와 이론적 고려 사항을 고려하여 관찰 연구 보고의 질을 개선하기 위한 역학 STROBE 권고안을 개발했다. STROBE statement은 논문의 제목, 초록, 서론, 방법, 결과 및 토론 부분에 대한 22개 항목의 체크리스트로 구성되어 있다. 18개 항목은 코호트연구, 환자 대조군 연구, 단면연구에 공통으로 적용되며, 4개 항목은 세가지 연구설계 각각에 따라 다르다. STROBE statement는 저자에게 관찰 연구에 대한 보고를 개선하는 방법에 대한 지침을 제공하고 심사자, 편집자 및 독자가 연구를 비판적으로 평가하고 해석하는 데 도움이 된다. 이 설명 문서는STROBE statement의 사용, 이해 및 보급을 향상 시키는 것이 목적이다. 각 체크리스트 항목의 의미와 근거가 제시되어 있다. 각 항목에 대해 하나 또는 여러 개의 출판된 예시 논문과 가능한 경우 관련 경험적 연구 및 방법론 문헌에대한 내용이 참고사항으로 제공된다. 유용한 흐름도의 예도 포함되어 있다. 본 문서 및 관련 웹사이트(http://www. strobe-statement.org/)는 관찰 연구 보고를 개선하는 데 유용한 자료가 될 것이다.

      • SCISCIESCOPUS

        <sup>131</sup>I-Anti CD20 Radioimmunotherapy of Relapsed or Refractory Non-Hodgkins Lymphoma: A Phase II Clinical Trial of a Nonmyeloablative Dose Regimen of Chimeric Rituximab Radiolabeled in a Hospital

        Turner, J. Harvey,Martindale, Andrew A.,Boucek, Jan,Claringbold, Phillip G.,Leahy, Michael F. Mary Ann Liebert 2003 Cancer Biotherapy & Radiopharmaceuticals Vol.18 No.4

        <P>In order to increase the availability and affordability of radioimmunotherapy of refractory or relapsed non-Hodgkins lymphoma, we developed and evaluated radioiodinated rituximab in an ongoing physician-sponsored Phase II Clinical Trial. The chimeric 1gG(1) anti CD 20 monoclonal antibody rituximab was radiolabeled with iodine-131 using a modified Chloramine T method with high radiochemical purity (98% +/- 0.82) and preservation of immunoreactivity. All patients received therapeutic loading doses of unlabeled rituximab (375 mg/m(2)) immediately prior to administration of tracer (200 MBq (131)I) or therapy (1.7-4.3 GBq (131)I) activities of (131)I-rituximab to provide additive immunotherapy and enhance tumor uptake of the radiolabeled antibody. Objective response rate (ORR) was 71% in 35 patients with a median follow-up of 14 months (range 4-28 months). Complete remission (CR) was achieved in 54% of patients, with median duration 20 months. Toxicity evaluation included an additional 7 patients followed for at least 3 months. Tracer dosimetry studies were performed in each patient and the whole body radiation absorbed dose was limited to a mean prescribed dose (MPD) of 0.75 Gy. Myelosuppression was reversible and in only 2 of 42 patients was grade IV hematological toxicity observed. No hemopoietic support was required in any patient. There was no instance of hemorrhage or infection in this group of patients in each of whom individual prospective dosimetry was performed prior to (131)I rituximab radioimmunotherapy for relapsed or refractory non-Hodgkins lymphoma.</P>

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