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Sultana, Arshiya,Fazmiya, MJA,Rahman, Khaleequr Cellmed Orthocellular Medicine and Pharmaceutical 2021 셀메드 (CellMed) Vol.11 No.2
Sphaeranthus indicus Linn. (Mundi) belongs to the family Compositae, Indian aromatic weed. Since the ancient time, its whole plant and flowers have great medicinal value. It is used for medicinal purpose in Unani and other traditional medicines as a blood purifier, aphrodisiac, eye tonic, tonic for vital organs, and anti-inflammatory properties. Hence, useful for neurological, eyes, cardiac, gastrointestinal, integument and urogenital disorders. This article intent to highlight the Unani ethnomedicinal properties and therapeutic uses, other traditional medicinal properties, to signify its potential in the treatment of various ailments as mentioned in Unani medicine and likewise to survey its phytoconstituents, pharmacological and clinical studies. Thisplant details were explored in classical Unani texts for its ethnobotanical Unani description, temperament (Mizaj), medicinal properties and therapeutic uses. Further, for phytochemicals and pharmacological/clinical studies information various scientific search engines such as PubMed, Science Direct, Ovid, Springer, Medline, Research Gate and Google Scholar were browsed. All relevant articles up to 2020 were referred including 24 Classical Unani and Medicinal plant books, 60 research and review papers. Mundi has been used in Unani and other traditional medicine for ages and used in the aforementioned ailments. The organic phytoconstituents include alkaloids, glycosides, saponins, tannins, resins, flavonoids, steroids, proteins volatile oils, sterol and terpenoid. In-vitro or in- Vivo studies have proven pharmacological activities of S. indicus such as anti-oxidant, anti-inflammatory, antimicrobial, antimutagenic, immunomodulatory, anti-ulcer, anti-pyretic, neuroprotective, hepatoprotective, hypoglycemic, antiageing and anti-cancer Hence, the aforesaid ethnomedicinal and therapeutic uses, pharmacological and clinical research studies rationalize the potential benefits of S. indicus mentioned in the classical Unani literature. However, future randomized clinical trials are proposed to approve its efficacy and safety for various ailments.
Effect of Marham-i-Raal on Episiotomy Wound Healing: A Single-Arm pre-and post-treatment study
Sultana, Arshiya,Joonus, Aynul Fazmiya Mohamed,Rahman, Khaleequr Cellmed Orthocellular Medicine and Pharmaceutical 2021 셀메드 (CellMed) Vol.11 No.4
Episiotomy is the commonest obstetrics intervention in the world to reduce severe perineal injuries. Its prevalence is 43% to 100% in primiparous women in Asia. Further, worldwide approximately 10-95% of pregnant women undergo episiotomy incision during birth. Delay in wound healing probably increases the risk of wound infection, changes the muscular structure, and ultimately causes muscle tone loss. So, wound care is of specific significance to postnatal maternal outcomes. Hence, this case study aimed to evaluate the effect of Marham-i-Raal in episiotomy wound healing and pain relief. The study was conducted in eleven postpartum primi or multipara pregnant women aged between group 19 and 35 years with term gestational age, singleton pregnancy in a cephalic presentation who had a normal vaginal delivery with mediolateral episiotomy, without a perineal tear, and perineal hematoma. Externally, application of Marham-i-Raal 2g on episiotomy incisional wound, twice a day for 10 days was advised. Wound healing of episiotomy and pain intensity was assessed with REEDA ["redness, oedema, ecchymosis, discharge and approximation of the edges"] scoring and VAS scoring for pain intensity respectively. At one hour (baseline), the REEDA mean score of eleven patients was 3.90±1.04 whereas on day 7-10 it was 0.18±0.40 with statistically significant difference (p<0.001). The VAS mean score at one hour was 6.90±1.22 whereas on day 7-10 it was 0.72±0.78 with a statistically significant difference (p<0.001). Marham-i-Raal would be effective in episiotomy wound healing and reducing pain intensity. Further, randomized double-blind controlled trials in large sample size are recommended.