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      • KCI등재

        SSD-Mobilenet과 ResNet을 이용한 모바일 기기용 자동차 번호판 인식시스템

        김운기,Fatemeh Dehghan,조성원 (사)한국스마트미디어학회 2020 스마트미디어저널 Vol.9 No.2

        This paper proposes a vehicle license plate recognition system using light weight deep learning models without high-end server. The proposed license plate recognition system consists of 3 steps: [license plate detection]-[character area segmentation]-[character recognition]. SSD-Mobilenet was used for license plate detection, ResNet with localization was used for character area segmentation, ResNet was used for character recognition. Experiemnts using Samsung Galaxy S7 and LG Q9, accuracy showed 85.3% accuracy and around 1.1 second running time. 본 논문은 고성능의 서버 없이 안드로이드 스마트폰 단독으로 동작할 수 있도록 경량화 딥러닝 모델을 사용하여 구현한 자동차 번호판 인식 시스템을 제안한다. 자동차 번호판 인식시스템은 [번호판검출]-[문자영역 분할]-[문자인식]으로 3단계의 과정으로 구성되며, 번호판검출은 SSD-Mobilenet, 문자영역 분할은 ResNet에 localization을 추가하여 사용하였고 문자인식은 ResNet을 이용하여 구현하였다. 테스트한 기기는 삼성 갤럭시 S7, LG Q9이며 정확도는 약 85.3%, 실행속도는 약 1.1초가 소요된다.

      • SCOPUSKCI등재

        Stereological study of testes following experimentally-induced unilateral cryptorchidism in rats

        Javad Sadeghinezhad,Fatemeh Yarmahmoudi,Mohammad Mehdi Dehghan,Saeed Farzad Mohajeri,Ehsan Roomiani,Hadis Bojarzadeh,Mahdi Aghabalazadeh Asl,Ava Saeidi,Margherita De Silva The Korean Society for Reproductive Medicine 2023 Clinical and Experimental Reproductive Medicine Vol.50 No.3

        Objective: Cryptorchidism is one of the main causes of infertility and can result in testicular cancer. This study aimed to present quantitative data on the damage caused by cryptorchidism using stereological analysis. Methods: Thirty newborn rats were randomly divided into control and experimental groups. The experimental group underwent surgery to induce unilateral cryptorchidism in the left testis, whereas the control group underwent a sham surgical procedure 18 days after birth. The testes were removed at designated time points (40, 63, and 90 days after birth) for stereological evaluation and sperm analysis. Total testicular volume, interstitial tissue volume, seminiferous tubule volume and length, and seminiferous epithelium volume and surface area were measured. Other parameters, such as sperm count, sperm morphology, and sperm tail length, were also examined. Results: Statistically significant differences (p<0.05) were observed between the experimental and the control groups at different ages regarding the volumes of various parameters, including the surface area of the germinal layer, the length of the seminiferous tubules, sperm count, and sperm morphology. However, no significant differences were observed in the epithelial volume and the sperm tail length of the groups. Conclusion: Given the substantial effect of cryptorchidism on different testicular parameters, as well as the irreversible damage it causes in the testes, it is important to take this abnormality seriously to prevent these consequences.

      • Nonlinear Model-Free Control and ARX Modeling of Industrial Motor

        Maryam Sarostad,Farzin Piltan,Fatemeh Dehghan Ashkezari,Nasri B. Sulaiman 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.12

        System identification is one of the main challenges in real time control. To design the best controller for linear or nonlinear systems, mathematical modeling is the main challenge. To solve this challenge conventional and intelligent identification are recommended. The second important challenge in the field of control theory is, design high-performance controller. To improve the performance of controller, two factors are very important: 1) high performance mathematical or intelligent modeling, 2) chose the best controller for the system. This paper has two main objectives: after data collection from position motor from industry the first objective is modeling and system identification based on Auto-Regressive with eXternal model input (ARX) and defined Z-function and Sfunction and the second objective is; design the high-performance controller to have the minimum rise time and error.

      • Dendrosomal Curcumin Inhibits Metastatic Potential of Human SW480 Colon Cancer Cells through Down-regulation of Claudin1, Zeb1 and Hef1-1 Gene Expression

        Esmatabadi, Mohammad Javad Dehghan,Farhangi, Baharak,Safari, Zahra,Kazerooni, Hanif,Shirzad, Hadi,Zolghadr, Fatemeh,Sadeghizadeh, Majid Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

        Colon cancer is one of the leading causes of cancer-associated death worldwide. The prognosis for advanced colorectal cancers remains dismal, mainly due to the propensity for metastatic progression. Accordingly, there is a need for effective anti-metastasis therapeutic agents. Since a great body of research has indicated anticancer effects for curcumin, we investigated the effects of dendrosomal curcumin (DNC) on cellular migration and adhesion of human SW480 cells and possible molecular mechanisms involved. Different methods were applied in this study including MTT, Scratch and adhesion assays as well as real-time PCR and transwell chamber assays. Based on the results obtained, DNC inhibits metastasis by decreasing Hef 1, Zeb 1 and Claudin 1 mRNA levels and can reduce SW480 cell proliferation with $IC_{50}$values of 15.9, 11.6 and $7.64{\mu}M$ at 24, 48 and 72h post-treatment. Thus it might be considered as a safe formulation for therapeutic purpose in colorectal cancer cases.

      • KCI등재

        Down-regulation of the autophagy gene, ATG7, protects bone marrow-derived mesenchymal stem cells from stressful conditions

        Sedigheh Molaei,Mehryar Habibi Roudkenar,Fatemeh Amiri,Mozhgan Dehghan Harati,Marzie Bahadori,Fatemeh Jaleh,Mohammad Ali Jalili,Amaneh Mohammadi Roushandeh 대한혈액학회 2015 Blood Research Vol.50 No.2

        Background Mesenchymal stem cells (MSCs) are valuable for cell-based therapy. However, their applicationis limited owing to their low survival rate when exposed to stressful conditions. Autophagy, the process by which cells recycle the cytoplasm and dispose of defectiveorganelles, is activated by stress stimuli to adapt, tolerate adverse conditions, or triggerthe apoptotic machinery. This study aimed to determine whether regulation of autophagywould affect the survival of MSCs under stress conditions. Methods Autophagy was induced in bone marrow-derived MSCs (BM-MSCs) by rapamycin, andwas inhibited via shRNA-mediated knockdown of the autophagy specific gene, ATG7. ATG7 expression in BM-MSCs was evaluated by reverse transcription polymerase chainreaction (RT-PCR), western blot, and quantitative PCR (qPCR). Cells were then exposedto harsh microenvironments, and a water-soluble tetrazolium salt (WST)-1 assay was performedto determine the cytotoxic effects of the stressful conditions on cells. Results Of 4 specific ATG7-inhibitor clones analyzed, only shRNA clone 3 decreased ATG7expression. Under normal conditions, the induction of autophagy slightly increased theviability of MSCs while autophagy inhibition decreased their viability. However, understressful conditions such as hypoxia, serum deprivation, and oxidative stress, the inductionof autophagy resulted in cell death, while its inhibition potentiated MSCs to withstandthe stress conditions. The viability of autophagy-suppressed MSCs was significantlyhigher than that of relevant controls (P<0.05, P<0.01 and P<0.001). Conclusion Autophagy modulation in MSCs can be proposed as a new strategy to improve their survivalrate in stressful microenvironments.

      • KCI등재

        Down-regulation of the autophagy gene, ATG7, protects bone marrow-derived mesenchymal stem cells from stressful conditions

        Sedigheh Molaei,Mehryar Habibi Roudkenar,Fatemeh Amiri,Mozhgan Dehghan Harati,Marzie Bahadori,Fatemeh Jaleh,Mohammad Ali Jalili,Amaneh Mohammadi Roushandeh 대한혈액학회 2015 Blood Research Vol.50 No.2

        Background Mesenchymal stem cells (MSCs) are valuable for cell-based therapy. However, their applicationis limited owing to their low survival rate when exposed to stressful conditions. Autophagy, the process by which cells recycle the cytoplasm and dispose of defectiveorganelles, is activated by stress stimuli to adapt, tolerate adverse conditions, or triggerthe apoptotic machinery. This study aimed to determine whether regulation of autophagywould affect the survival of MSCs under stress conditions. Methods Autophagy was induced in bone marrow-derived MSCs (BM-MSCs) by rapamycin, andwas inhibited via shRNA-mediated knockdown of the autophagy specific gene, ATG7. ATG7 expression in BM-MSCs was evaluated by reverse transcription polymerase chainreaction (RT-PCR), western blot, and quantitative PCR (qPCR). Cells were then exposedto harsh microenvironments, and a water-soluble tetrazolium salt (WST)-1 assay was performedto determine the cytotoxic effects of the stressful conditions on cells. Results Of 4 specific ATG7-inhibitor clones analyzed, only shRNA clone 3 decreased ATG7expression. Under normal conditions, the induction of autophagy slightly increased theviability of MSCs while autophagy inhibition decreased their viability. However, understressful conditions such as hypoxia, serum deprivation, and oxidative stress, the inductionof autophagy resulted in cell death, while its inhibition potentiated MSCs to withstandthe stress conditions. The viability of autophagy-suppressed MSCs was significantlyhigher than that of relevant controls (P<0.05, P<0.01 and P<0.001). Conclusion Autophagy modulation in MSCs can be proposed as a new strategy to improve their survivalrate in stressful microenvironments.

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