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RISS 인기검색어
- 검색키워드
- 저자 : Fábio Hissachi Tsuji (검색결과 2 건)
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Fábio Hissachi Tsuji,Renato Caretta Chambó,Aparecido Donizeti Agostinho,José Carlos Souza Trindade Filho,Carlos Márcio Nóbrega de Jesus 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.2
Purpose: To assess the pain intensity of patients administered midazolam and fentanylcitrate before undergoing transrectal ultrasound-guided prostate biopsy. Materials and Methods: This was a study in patients with different indications for prostatebiopsy in whom 5 mg of midazolam and 50 μg of fentanyl citrate was administeredintravenously 3 minutes before the procedure. After biopsy, pain was assessed by useof a visual analogue scale (VAS) in three stages: VAS 1, during probe introduction; VAS2, during needle penetration into prostate tissue; and VAS 3, in the weeks followingthe exam. Pain intensity at these different times was tested with stratification by age,race, education, prostate volume, rebiopsy, and anxiety before biopsy. Pain was rankedaccording to the following scores: 0 (no pain), 1–3 (mild pain), 4–7 (moderate pain), and8–10 (severe pain). Statistical analysis was performed by using Kruskal-Wallis andWilcoxon two-tailed tests with a significance of 5%. Results: Pain intensity was not influenced by any risk factors. The mean VAS 1 scorewas 1.95±1.98, the mean VAS 2 score was 2.73±2.55, and the mean VAS 3 score was0.3±0.9, showing greater pain at the time of needle penetration than in other situations(VAS 2>VAS 1>VAS 3, p=0.0013, p=0.0001, respectively). Seventy-five percent of patientsreported a VAS pain scale of less than 3.1 or mild pain. Conclusions: Intravenous sedation and analgesia with midazolam and fentanyl citrateis a good method for reducing pain caused by prostate biopsy, even during probeinsertion.
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What Is the Ideal Core Number for Ultrasound-Guided Prostate Biopsy?
Renato Caretta Chambó,Fábio Hissachi Tsuji,Flávio de Oliveira Lima,Hamilto Akihissa Yamamoto,Carlos Márcio Nóbrega de Jesus 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.11
Purpose: We evaluated the utility of 10-, 12-, and 16-core prostate biopsies for detectingprostate cancer (PCa) and correlated the results with prostate-specific antigen (PSA)levels, prostate volumes, Gleason scores, and detection rates of high-grade prostaticintraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP). Materials and Methods: A prospective controlled study was conducted in 354 consecutivepatients with various indications for prostate biopsy. Sixteen-core biopsy specimenswere obtained from 351 patients. The first 10-core biopsy specimens were obtainedbilaterally from the base, middle third, apex, medial, and latero-lateral regions. Afterward, six additional punctures were performed bilaterally in the areas more lateralto the base, middle third, and apex regions, yielding a total of 16-core biopsyspecimens. The detection rate of carcinoma in the initial 10-core specimens was comparedwith that in the 12- and 16-core specimens. Results: No significant differences in the cancer detection rate were found between thethree biopsy protocols. PCa was found in 102 patients (29.06%) using the 10-core protocol,in 99 patients (28.21%) using the 12-core protocol, and in 107 patients (30.48%) usingthe 16-core protocol (p=0.798). The 10-, 12-, and 16-core protocols were comparedwith stratified PSA levels, stratified prostate volumes, Gleason scores, and detectionrates of HGPIN and ASAP; no significant differences were found. Conclusions: Cancer positivity with the 10-core protocol was not significantly differentfrom that with the 12- and 16-core protocols, which indicates that the 10-core protocolis acceptable for performing a first biopsy.
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