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Malignant Peripheral Nerve Sheath Tumor in Descending Colon - A Case Report -
YoungS. Park,SungJig Lim,WooHo Kim,EuiKeun Ham 대한병리학회 2002 Journal of Pathology and Translational Medicine Vol.36 No.3
We report a unique case of malignant peripheral nerve sheath tumor (MPNST) of colon, not associated with neurofibromatosis or parasite infection. The tumor presented as an encircling mass in descending colon causing obstruction with numerous metastatic lesions in a 43-year-old man. The tumor was largely composed of spindle cells which showed strong positivity for vimemtin, S-100 protein and Leu-7. The tumor often exhibited epithelioid feature where tumor cells were weakly positive for cytokeratin.
Intestinal Metastasis of Osteosarcoma Presenting with Intussusception - A Case Report -
Seong-Ho Yoo,Min-A Kim,KyuJoo Park,JoonKoo Han,SangHoon Lee,ChongJai Kim,EuiKeun Ham 대한병리학회 2002 Journal of Pathology and Translational Medicine Vol.36 No.4
Metastatic osteosarcoma most commonly affects the lungs and other bones. Intestinal intussusception caused by metastatic osteosarcoma is very rare. We report a case of metastatic osteosarcoma of the intestine in a 39-year-old female. She underwent surgical resection of the left femur due to osteosarcoma and received additional chemotherapy 3 years ago. Pulmonary metastasis was found two years later and the patient complained of abdominal pain, nausea and vomiting after 8 months following excision of the lung nodules. Abdominal computed tomography revealed intussusception with a suspected polypoid mass in the distal portion of the jejunum. The histologic findings of the resected bowel were those of osteosarcoma. This is the first case of documented intestinal metastasis of osteosarcoma in Korea. It is suggested that the tumor metastasis to the small intestine should be considered in patients with previous osteosarcoma, when the patient presents with acute abdominal symptoms and intussusception.