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Eshun, Derek,Saraf, Rabya,Bae, Soochan,Jeganathan, Jelliffe,Mahmood, Feroze,Dilmen, Serkan,Ke, Qingen,Lee, Dongwon,Kang, Peter M.,Matyal, Robina American Physiological Society 2017 environmental and exercise physiology Vol.122 No.6
<P>NEW & NOTEWORTHY Our research project proposes a novel method for drug delivery. Our patented PVAX nanoparticle can detect areas of ischemia and oxidative stress. Although there have been studies about delivering angiogenic molecules to areas of ischemic injury, there are drawbacks of nonspecific delivery as well as short half-lives. Our study is unique because it can specifically deliver NPY3-36 to ischemic tissue and appears to extend the amount of time therapy is available, despite NPY3-36's short half-life.</P>