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RISS 인기검색어
- 검색키워드
- 저자 : EDWARD K. CHOW (검색결과 2 건)
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EDWARD K. CHOW,BENJAMIN CHU,GENHONG CHENG,YU-CHONG TAI,ERIK PIERSTORFF,DEAN HO 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2007 NANO Vol.2 No.6
Serving as platforms for both cellular interrogation as well as biomembrane mimicry, biotic–abiotic functionalized materials, such as block copolymeric membranes, offer the opportunity for tailored biology, where specific embedded functionalities can be rapidly engineered, on demand, without the need for genetic processing. These versatile materials enable rapid, thin film deposition of a plethora of biologically-relevant materials at the air–water interface given their amphiphilic properties, meaning that they possess alternating hydrophilic and hydrophobic components. This property confers to these materials the ability to be transferred to a wide range of substrates and materials, further enhancing their interfacial versatility. In addition, their biologically-inert, and tunable, thickness-dependent insulating properties serve as ideal bio-active substrates while maintaining the functionality of the integrated molecule (e.g., protein, effector molecule, etc.). Here, we report the application of a polyethyleneoxide–polymethylmethacrylate (PEO–PMMA) diblock and polymethyloxazoline–polydimethylsiloxane–polymethyloxazoline (PMOXA–PDMS–PMOXA) triblock copolymers as molecular anchors for tethering a broad spectrum of materials. These include carbon nanotubes for the fabrication of bioelectrodes to measure cytochrome c-mediated oxidation-reduction, as well as the anti-inflammatory molecule, dexamethasone, for the suppression of lipopolysaccharide (LPS)-induced inflammation in murine macrophages. As such, this work demonstrates the versatility, and broad applicability and impact of this platform approach towards the fabrication of multifunctional arrays of biologically-active surfaces for experimentation ranging from bio-electroactivity to studies of cellular immunity.
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Adam S.C. Siu,James K.F. Chow,Edward Hui,Mei M. Chong,Michel Dard 대한치과이식임플란트학회 2021 The Korean Academy of Implant Dentistry Vol.40 No.4
Bimaxillary immediate full-arch restorations can be prosthodontically, surgically, and esthetically demanding. State-of-the-art computer- assisted guided surgery can significantly improve the predictability and reliability of such procedures while reducing the chair time for the patient. This case report demonstrates how such procedures can be applied using an industrially outsourced service to assist implant planning and treatment preparation. A 63-year-old partially edentulous female with a failing dentition presented at our clinic. After medical assessment and the patient s request to avoid any edentulous episodes during treatment, a digitally guided bimaxillary full-arch reconstruction with an immediate restoration was performed within one session. The surgical and restorative procedures were performed as planned, allowing an immediate provisional restoration. The comparison of the planned and actual implant positions indicated slight inaccuracies between these positions. These deviations did not affect the immediate provisionalization, functionality, or esthetics of the immediate or final prosthetic rehabilitation. Fully digitally guided workflows represent a valuable tool for the efficient and reliable immediate transition from a failing dentition to a fixed reconstruction. The application of an outsourced and assisted digital planning service allows immediate access to digitally guided surgery and can improve efficiency. Deviations between planned and actual implant positions were most likely related to the rotational degrees of freedom around the teeth used for guide retention.
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