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- 저자 : Daisuke Eto (검색결과 1 건)
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Linear time-varying modeling of inter-organ regulatory system
Daisuke Eto,Takashi Nakakuki,Jun-ichi Imura 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11
In this study, we propose a linear time-varying model of the inter-organ regulatory system. It is well-known that the regulation of energy metabolism is highly controlled by complex metabolic pathways coupled among various organs. On the other hand, a malfunction of this regulatory system can induce various pathological conditions related to the metabolic syndrome, implying that homeostasis of energy expenditure in the inter-organ regulatory system can be treated as a control problem, given an appropriate mathematical model. Moderately abstracting the complex mechanisms and maintaining the comprehensiveness of the inter-organ networks, we construct a simple model comprised of 16 states and 31 rate equations. Since our model is described as a linear time-varying system, it is expected that various control theories can be applied for the model-based analysis of the inter-organ regulatory system.
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