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        Validation of low anterior resection syndrome score in Brazil with Portuguese

        Buzatti Kelly C.L.R.,Petroianu Andy,Laurberg Søren,Silva Rodrigo G.,Rodrigues Beatriz D.S.,Christensen Peter,Lacerda-Filho Antonio,Juul Therese 대한대장항문학회 2023 Annals of Coloproctolgy Vol.39 No.5

        Purpose: This study was performed to investigate the convergent validity, discriminative validity, and reliability of the Brazilian version of the low anterior resection syndrome (LARS) score in a population with low educational and socioeconomic levels. Methods: The LARS score was translated into the Portuguese language by forward- and back-translation procedures. In total, 127 patients from a public hospital in Brazil completed the questionnaires. The convergent validity was tested by comparing the LARS score with the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core Module 30 (QLQ-C30) and with patients’ self-reported quality of life. For the discriminative validity, we tested the ability of the score to differentiate among subgroups of patients regarding neoadjuvant radiotherapy, type of surgery, and tumor distance from the anal verge. The test-retest reliability was investigated in a subgroup of 36 patients who responded to the survey twice in 2 weeks. Results: The LARS score demonstrated a strong correlation with 5 of 6 items from the EORTC QLQ-C30 (P<0.05) and good concordance with patients’ self-reported quality of life (95.3%), confirming the convergent validity. The score was able to discriminate between subgroups of patients with different clinical characteristics related to LARS (P<0.001). The agreement between the test and retest showed that 86.1% of the patients remained in the same LARS category, and there was no significant difference between the LARS score numerical values (P=0.80), indicating good reliability overall. Conclusion: The Brazilian version of the LARS score is a valid and reliable instrument to assess postoperative bowel function in a population with low educational and socioeconomic levels.

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        The SPARC water vapor assessment II: intercomparison of satellite and ground-based microwave measurements

        Nedoluha, Gerald E.,Kiefer, Michael,Lossow, Stefan,Gomez, R. Michael,,mpfer, Niklaus,Lainer, Martin,Forkman, Peter,Christensen, Ole Martin,Oh, Jung Jin,Hartogh, Paul,Anderson, John,Bramstedt, Kl Copernicus GmbH 2017 Atmospheric Chemistry and Physics Vol.17 No.23

        <P>Abstract. As part of the second SPARC (Stratosphere-troposphere Processes And their Role in Climate) water vapor assessment (WAVAS-II), we present measurements taken from or coincident with seven sites from which ground-based microwave instruments measure water vapor in the middle atmosphere. Six of the ground-based instruments are part of the Network for the Detection of Atmospheric Composition Change (NDACC) and provide datasets that can be used for drift and trend assessment. We compare measurements from these ground-based instruments with satellite datasets that have provided retrievals of water vapor in the lower mesosphere over extended periods since 1996. We first compare biases between the satellite and ground-based instruments from the upper stratosphere to the upper mesosphere. We then show a number of time series comparisons at 0.46 hPa, a level that is sensitive to changes in H2O and CH4 entering the stratosphere but, because almost all CH4 has been oxidized, is relatively insensitive to dynamical variations. Interannual variations and drifts are investigated with respect to both the Aura Microwave Limb Sounder (MLS; from 2004 onwards) and each instrument's climatological mean. We find that the variation in the interannual difference in the mean H2O measured by any two instruments is typically ∼ 1%. Most of the datasets start in or after 2004 and show annual increases in H2O of 0-1 % yr−1. In particular, MLS shows a trend of between 0.5 % yr−1 and 0.7 % yr−1 at the comparison sites. However, the two longest measurement datasets used here, with measurements back to 1996, show much smaller trends of +0.1 % yr−1 (at Mauna Loa, Hawaii) and −0.1 % yr−1 (at Lauder, New Zealand). </P>

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