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        STAR-24K: A Public Dataset for Space Common Target Detection

        Chaoyan Zhang,Baolong Guo,Nannan Liao,Qiuyun Zhong,Hengyan Liu,Cheng Li,Jianglei Gong 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.2

        The target detection algorithm based on supervised learning is the current mainstream algorithm for target detection. A high-quality dataset is the prerequisite for the target detection algorithm to obtain good detection performance. The larger the number and quality of the dataset, the stronger the generalization ability of the model, that is, the dataset determines the upper limit of the model learning. The convolutional neural network optimizes the network parameters in a strong supervision method. The error is calculated by comparing the predicted frame with the manually labeled real frame, and then the error is passed into the network for continuous optimization. Strongly supervised learning mainly relies on a large number of images as models for continuous learning, so the number and quality of images directly affect the results of learning. This paper proposes a dataset STAR-24K (meaning a dataset for Space TArget Recognition with more than 24,000 images) for detecting common targets in space. Since there is currently no publicly available dataset for space target detection, we extracted some pictures from a series of channels such as pictures and videos released by the official websites of NASA (National Aeronautics and Space Administration) and ESA (The European Space Agency) and expanded them to 24,451 pictures. We evaluate popular object detection algorithms to build a benchmark. Our STAR-24K dataset is publicly available at https://github.com/Zzz-zcy/STAR-24K.

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        Effects of a novel marine natural product: pyrano indolone alkaloid fibrinolytic compound on thrombolysis and hemorrhagic activities in vitro and in vivo

        Ting Yan,Wen-Hui Wu,Tongwei Su,Jiajie Chen,Quangang Zhu,Chaoyan Zhang,Xiaoyu Wang,Bin Bao 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.8

        Fungi fibrinolytic compound 1 (FGFC1) is a novel marine natural product as a low-weight fibrinolytic pyranoindole molecule, whose thrombolytic effects were evaluated on FITC-fibrin (Fluorescein isothiocyanate, FITC) degradation methods in vitro and on acute pulmonary thromboembolism animal model in vivo. We determined the FGFC1 induced thrombolysis that stems from its fibrin(ogen)olytic activities as measured by fibrin(ogen) degradation products (FDPs) experiment, acute pulmonary thromboembolism animal model experiment, and euglobulin lysis assay. In vitro, measurement of FITCfibrin degradation revealed that fibrin hydrolysis occurred in a concentration-dependent manner of FGFC1 from 5 to 25 l mol/L. In vivo test of a classical acute pulmonary thromboembolism model in rat showed that when the injected dose was 5 mg/kg or above, FGFC1 was effectivein dissolution of extrinsic FITC-fibrin induced blood clots. Euglobulin lysis time (ELT) in FGFC1-treated rats was shortened 30 s compared with rats in the positive control group, which were injected with clopidogrel sulfate and single-chain urokinase-type plasminogen activator. As compared to the control, FGFC1 (5–25 mg/kg) did not significantly alter the formation of fibrinogen and FDPs in vivo. Our research indicates that FGFC1 presents pharmacodynamic action in both the thrombolysis and the hemolytic procedure, which can be characterized by fibrinogenolysis in blood and FDPs in plasma. In vivo, increasing fibrinolytic doses of FGFC1 from 5 to 25 mg/kg did not induce fibrinogenolysis when compared with control group, this result corresponds to that FGFC1 did not induce the increasing of FDPs (compared with the salinetreated control). It indicates that the FGFC1 may act as a novel thrombolytic agent and represent an effective approach to the treatment of thrombus without significant risk of hemorrhagic activity.

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