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- 저자 : Carlo Filice (검색결과 2 건)
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Limitations and artifacts in shear-wave elastography of the liver
Matthew Bruce,Orpheus Kolokythas,Giovanna Ferraioli,Carlo Filice,Matthew O’Donnell 대한의용생체공학회 2017 Biomedical Engineering Letters (BMEL) Vol.7 No.2
Recent studies have shown that real-time, twodimensionalshear-wave elastography (2D-SWE) canmonitor liver fibrosis by measuring tissue elasticity (i.e.,elastic modulus). Two clinical studies of 2D-SWE in theliver have shown that there are several practical issues thatcan compromise quantitation of liver tissue elasticity. Bothgeneral ultrasound (US) limitations and limitations in the2D-SWE method itself resulted in significant variability inestimated liver elasticity. The most common US limitationswere: poor acoustic window, limited penetration, and rib/lung shadows. The most common 2D-SWE limitationswere: reverberations under the liver capsule, respiratory/cardiac motion, and vessel pulsation/loss of SWEsignal. Based on these studies, scan protocols have beenoptimized to minimize the influence of these limitations onliver elasticity quantification. These refined protocolsshould move non-invasive SWE closer to becoming thepreferred tool to diagnose and manage many chronic diseasesof the liver.
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Giovanna Ferraioli,Ambra Raimondi,Annalisa De Silvestri,Carlo Filice,Richard G.Barr 대한초음파의학회 2023 ULTRASONOGRAPHY Vol.42 No.3
Purpose: This study’s primary aim was to assess factors affecting ultrasound attenuation coefficient (AC) measurement repeatability using the Canon ultrasound (US) system. The secondary aim was to evaluate whether similar results were obtained with other vendors’ AC algorithms. Methods: This prospective study was performed at two centers from February to November 2022. AC was obtained using two US systems (Aplio i800 of Canon Medical Systems and Arietta 850 of Fujifilm). An algorithm combining AC and the backscatter coefficient was also used (Sequoia US System, Siemens Healthineers). To evaluate inter-observer concordance, AC was obtained by two expert operators using different transducer positions with regions of interest (ROIs) varying in terms of depth and size. Intra-observer concordance was evaluated on measurements performed intercostally, subcostally, and in the left liver lobe. Lin’s concordance correlation coefficient was used. Results: Thirty-four participants (mean age, 49.4±15.1 years; 18 females) were studied. AC values progressively decreased with depth. The measurements in intercostal spaces on bestquality US images using a 3-cm ROI with its upper edge 2 cm below the liver capsule during breath-hold showed the highest intra-observer and inter-observer concordance (0.92 [95% confidence interval, 0.88 to 0.95] and 0.89 [0.82 to 0.96], respectively). Measurements in the left lobe showed the lowest intra-observer and inter-observer concordance (0.67 [0.43 to 0.90] and 0.58 [0.12 to 1.00], respectively). Intercostal space measurements also had the highest repeatability for the other two ultrasound systems. Conclusion: AC values obtained in intercostal spaces on best-quality images using a 3-cm ROI placed with its top 2 cm below the liver capsule were highly repeatable.
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