양측 쇄골하동맥 및 양측 신동맥 협착을 동반한 Takayasu 동맥염 1예

임선호,임수빈,오석규,이재홍,정진원,박양규,박옥규,소병준,노병석 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.8

인체감염 동양안충(Thelazia callipaeda)에 대하여

안영겸,이규재,양우익,정평림,김기수,백병태 연세대학교 원주의과대학 1993 원주의대논문집 Vol.6 No.1

연작업자들에서의 δ -aminolevulinic acid dehydratase 유전형질의 다형성이 신기능에 미치는 영향

안익수,황보영,김용배,리갑수,이성수,장봉기,함정오,안규동,이병국 순천향대학교 산업의학연구소 2001 순천향산업의학 Vol.7 No.1

δ-aminolevulinic acid hehydratase (ALAD) is a polymorphic enzyme that has two alleles, ALAD1 (ALAD1-1 as phenotype) and ALAD2 (ALAD1-2 or ALAD2-2 as phenotype). ALAD genotype has been reported to modify the toxicokinetics of lead. To investigate the influence of ALAD genotype polymorphism on renal function in lead workers, author studied 1022 male lead workers and 149 non lead workers in the same industries. For the cross-sectional renal function indices, blood urea nitrogen (BUN), serum creatinine, uric acid and total protein were selected. Blood lead and blood zinc protoporphyrin were also measured as indices of lead exposure. Information on weight, age, job duration, smoking & drinking history were collected. Following results are as follows: 1. Whereas the mean (standard deviation) of blood lead and blood ZPP of lead workers were 27.2±12.5 ㎍/㎗ and 57.7±37.8 ㎍/㎗, those of non-lead workers in the same premises were 14.9±6.5 ㎍/㎗ and 44.6± 15.8 ㎍/㎗ respectively. The difference of mean blood lead and blood ZPP between two groups were statistically significant. 2. Whereas the prevalence of the variant allele, ALAD2 in 1022 lead workers was 10.2 %, the prevalence of that in 149 non-lead workers was 7.4 %. But there was no difference of prevalence between two groups. 3. The mean±standard deviation of blood lead of subjects with ALAD1 was 25.5± 12.7 ㎍/㎗ and was slightly lower than that of subjects with ALAD2 (26.5±10.9 ㎍/㎗), and the mean±standard deviation of blood ZPP of subjects with ALAD1 was slightly higher than that of subjects with ALAD2 (56.7±37.3 ㎍/㎗ vs 48.9±18.6 ㎍/㎗). But the differences of blood lead and blood ZPP between two genotypes were not statistically significant. 4. There were no differences of cross-sectional renal function indices (BUN, serum creatinine, uric acid and total protein) either by lead workers and non-lead workers or two genotypes. 5. In multiple regression analysis of ALAD genotype on BUN after controlling for possible confounders (sex, weight, job duration, smoking and drinking status), the mean of BUN in ALAD2 subjects was 0.629 ㎎/㎗ lower than ALAD1 subjects with a weak statistical significance (p=0.07). But in logistic analysis of ALAD genotype on median value of BUN revcaled that subjects of ALAD2 genotype were 32% less likely to have median value or more of BUN than subjects of ALAD1 with odd ratio of 0.618 (95% confidence interval 0.411-0.920). 6. In multiple regression analysis of ALAD genotype on serum creatinine after controlling for possible confounders (sex, weight, job duration, smoking and drinking status), the mean of serum creatinine in ALAD2 subjects was 0.0271 ㎎/㎗ lower than ALAD1 subjects with statistical significance (p=0.02). On the other hand, in logistic analysis of ALAD genotype on median value of serum creatinine revealed that subjects of ALAD2 genotype were 30% less likely to have median value or more of scrum creatinine than subjects of ALAD1 with odd ratio of 0.700 (95% confidence interval 0.442-1.080). With the above results, it was found that the variant allcle, ALAD2 appeared to modify the association of lead and renal function and ALAD2 genotype may be supportive for the protective effect of lead.

저속 충격을 받는 적층판의 충격거동과 손상에 관한 연구

안국찬,김규수,박승범,황병선 한국산업안전학회 2002 한국안전학회지 Vol.17 No.1

This paper presents the impact behavior and damage of laminated composite plates subjected to the low-velocity impact. For this purpose, a pendulum impact test for impact behavior and C-scan for impact damage are done. Test materials are carbon/epoxy laminated composite plates and stacking sequences [0/90]_4, [0/45_2/-45]_s, [45_2/-45/90]_s, [0/45/-45/90]_s and [0/26/51/77/-77/-51/-26/0].

파인만 연산계산에서의 약수렴정리

안병무,한명규 순천향대학교 기초과학연구소 2011 순천향자연과학연구 논문집 Vol.17 No.2

비가환 연산자에 대한 파인만 연산계산이 구간에서 연속 측도를 이용하여 연구되었고 또한 측도들이 연속인 경우 얽힌 것을 푸는 함수들의 연산자에 관한 수렴정리에 대하여 연구 되었다. 이 논문에서는 연산자들이 가분 힐베르트 공간에서 함수 값을 갖는 유계 선형함수인 경우에 시간에 대하여 독립적인 수렴정리들을 연구하였다.

직업적 연폭로가 일부 신경행동학적 검사수행에 미치는 영향

안익수,안현철,김용배,리갑수,김화성,황규윤,최은,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

In order to investigate that blood lead levels of lead exposed workers is associated with decreased performance in neurobehavioral tests in adults, we investigate 78 workers in a battery industry. Three items among neurobehavioral core test battery of World Health Organization, including digit span, Santa ana dexterity, digit symbol were administered to workers occupationally lead exposed workers by operational guide for the WHO neurobehavioral core test battery. Blood lead (PbB) and zinc protoporphyrin in whole blood (ZZP) were selected as an index of lead exposure. Detailed occupational history such as exposed agent, age, work duration, smoking and drinking habits, were recorded as confounding factors. After controlling age, the results of digit span and digit symbol among the neurobehavioral tests were significant contributed by PbB.

제조에 對한 文獻的 考察

안태규,최병렬,송기철,이용연,유화승,서상훈,최우진,조정효,이연월,손창규,조종관 대전대학교 한방병원 2001 惠和醫學 Vol.10 No.1

In the literatual study on Holotrichia, the results were obtained as follows ; 1. Holotrichia is larva of Holotrichia diomphalia Bates etc. powder or liquor of Holotrichia is used medically. 2. Appearance of Holotrichia is shape of kidney, yellowish color. 3. The oriental characters of Holotrichia is warm, toxicant, salty. 4. The significant efficancy of Holotrichia is breaking the stagnant blood. 5. Holotrichia can be applied to the diseases related to thrombosis, and recover the demage of liver. 6. Holotrichia avails Liver diseases such as Hepatitis, Liver cirrhosis, Hepatosplenomegaly, Hepatoma etc.

國內産 山野草의 化學的인 組成 : 第1報 南方型 草種에 對하여 Ⅰ. Chemical Composition of Southern type herbages

安炳弘,金丙鎬,韓仁圭 진주농과대학 1970 진주농과대학 연구논문집 Vol.- No.9

國內産 山野草의 一般成分을 調査하기 위하여 本試驗을 實施했는 바 그 結果는 다음과 같다. 1. 禾本科野草의 6月 以後의 固形物含量은 90% 以上이었다. 2. 禾本科野草의 蛋白質含量은 平均 10% 內外인데 時期가 지날수록 相當히 感少되었다. 3. 禾本科野草의 粗纖維含量은 平均 31.5% 內인데 時期가 지날수록 漸次 增加되었다. 4. 禾本科野草의 脂肪, 灰分 및 NFE 含量은 大體로 年中 비슷한 含量이었다. 5. 荳科野草의 6月 以後의 固形物 含量은 91% 以上이었다. 6. 荳科野草의 蛋白質含量은 平均 17% 內外인데 時期가 지날수록 漸次 感少되었다. 7. 荳科野草의 粗纖維含量은 平均 29% 정도인데 時期가 지날수록 漸次 增加되었다. 8. 荳科野草의 脂肪, 灰分 및 NFE의 全量은 大體로 年中 비슷한 含量이었다. 9. 차풀의 蛋白質은 平均 14%정도였다. To investigate the chemical composition of native herbages in korea, this experiment was carried out. The results obtained here are as follows: 1. The contents of dry matter in the wild grasses after June was above 90%. 2. protein contents in the wild grasses was approximately 10% and that of protein decreased as the stage of maturity progressed. 3. The contents of crude fiber in the wild grasses was 31.5% on an average and that of crude fiber increased considerably as the stage of maturity advanced. 4. But, the contents of fat, ash and NFE in the wild grasses did not highly changed through the year. 5. The contents of dry matter in the wild legumes after June was above 91% approximately. 6. protein contents in the wild legumes was higher than 17% but that of protein decreased progressively as the stage of maturity advanced. 7. The contents of crude fiber in the wild legumes was 29% on an average and that of crude fiber increased considerably as the stage of maturity progressed. 8. However, the contents of fat, ash and NFE in the wild legumes did not highly changed through the year. 9. The contents of protein in the Cassia nomame was 14% approximately.

간헐포기MBR공정에서의 하수처리성능과 미생물의 군집구조해석

임병란,안규홍 대한상하수도학회 2002 상하수도학회지 Vol.16 No.6

The objective of this study was investigated for the microbial community structure and treatment performance of domestic wastewater in lab-scale submerged membrane bioreactor operated with anoxic-oxic cycles. Respiratory quinone profiles were applied as tools for identifying different bacterial populations. The cycle time program of bioreactor was control under anoxic/oxic of 60/90 minutes with an hydraulic retention time of 8.4 hrs. The average COD_Cr removal efficiency of domestic wastewater was as high as 93%. The results showed complete nitrification of NH_4^+-N generated during oxic period and up to 50% of the total nitrogen could be denitrified. The dominant quinone types of suspended microorganisms in bioreactor were ubiquinone (UQ)-8, -10, followed by menaquinone (MK)-6, and MK-7 for anoxic period, but those for oxic period were UQ-8, MK-6, followed by UQ-10 and MK-7. The microbial diversities of bioreactor at anoxic and oxic periods, calculated based on the composition of all quinones were 10.4 and 12.2-11.8, respectively. The experimental results showed that the microbial community structure in the submerged membrane bioreactor treating domestic wastewater was slightly affected by intermittent aeration.

THI 증상군에 영향을 주는 건강관련요인 연구

한창규,황규윤안규동,이병국 순천향대학교 산업의학연구소 1996 순천향산업의학 Vol.2 No.1

To obtain the prevalence rate of health related symptoms of white collar workers who were not exposed to hazardous agent and to investigate the relationship between subjective symptoms & health related variables, 11,266 subjects who were employed for government organization & private educational institute in Seoul, Chungnam, Kyungpook area were studied in order to provide basic information for the health management of white collar workers. All th subjects visited hospitals to take biannual health examination provided Medical Insurance Association for the purpose of screening of several important adult disease. Todai Health Index(THI) questionnaire which is modified questionnaire of CMI made by Todai was selected for the questionnaire form of this study. During hospital visit for health examination, Todai Health Index questionnaire of 88 questions were filled up by the subjects themselves and confirmed by medical doctor. Major findings obtained were as follows: 1. The abnormal rate of screening test was 22.7% in male, 8.5% in female, and 19.2% in total subjects. The prevalence rate of disease was 13.2% in male, 4.9% in female & 10.9% in total subjects. 2. The prevalence rate of all diseases increased by age and th prevalence rate of male subjects were higher than female subjects in all age categories except that of the anemic disease. 3. While highest prevalence rate in all subjects was observed in cardiovascular disease(4.8%), the prevalence rate were 3.4% in liver disease, 2.0% in diabetic disease, 1.9% in pulmonary tuberculosis & chest disease, 0.5% in kidney disease and 0.4% anemic disease. Liver disease was more frequent in age group of below 29 years old and age group of 30-39 years old, but in older age groups(40-49 years old, above 50 years), cardiovascular disease was most frequent. 4. The highest mean score of THI symptom category was mental instability and the lowest one was skin & anus symptoms. The most frequent symptom of THI was "think a lot before action" in nervousness symptom category and mean scores of the female subjects in all symptom category were higher that those of male subjects. 5. In symptoms and signs of recent 3 months, the most frequent symptom and sign was "generalized fatigue" and mean score of it was 1.85. Multiple comparison analysis of health related factors revealed that "illness in health status" was the highest score(23.54) in male and sometimes drink & drunken in alcohol intake was th highest score(26.13) in female. 6. In multiple comparison analysis, health related factors such as health status, health management, diet habit, taste character, vegetable intake, coffee & beverage, alcohol intake were found to be associated with th overall THI symptom category in both sex and age and smoking in male, type of job in female were associated THI symptom category. 7. In stepwise multiple regression analysis of mean score of THI symptom category(dependent variable) and health related factors(independent variables), the variables of health health status, taste character and alcohol were contributed to THI symptom category in order and the highest correlation coefficient(r) was 0.4085 in male and 0.397 in female in health status of mental instability. 8. The significant health factors contribution to THI symptoms score in male subjects were, in multiple regression analysis with THI symptom category with dependent variable and health related factors with independent variables, health status, diet habit, alcohol intake, taste character, final diagnosis, coffe & beverage, type of job, age, smoking, health management, meat intake and in female were health status, type of job, diet habit alcohol intake, coffee & beverage consumption, screening test, age, health management. The most significant contribution factor among health related variables was health status in over all THI symptom category.