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In vitro Synergism of Antimutagenic and Antioxidant Activities of Phoenix dactylifera Fruit
Bushra Sultana,Benish Fatima,Muhammad Mushtaq 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.3
The availability of total phenolics of date flesh(Pheonix dactylifera) in aqueous and acidified methanoland in vitro synergism of their antimutagenic and antioxidantactivities were investigated. The antimutagenic activities ofdate flesh extracts tested against Salmonella strains TA-98and TA-100 using Ames bacterial testing were in the rangeof 36.47 to 79.74% against the standard mutagenspotassium dichromate and sodium azide. The antioxidantactivities assessed as maximal inhibitory concentrations(IC50) for DPPH radicals and linoleic acid peroxidationinhibition were 812.90 to 2,076.10 μg/mL and 54.43 to80.89%, respectively. The total phenolic contents of dateflesh extracts (35.76 to 114.09mg/g of gallic acid equivalents)were found to be correlated with the biological activities. Use of 0.5 N acidified methanol was efficient for extractionof phenolic compounds with retained antioxidant andantimutagen activities. Dates are a good candidate as asource for development of chemotherapeutic drugs,nutracueticals, and functional food ingredients.