Activity of sputtered gold particles layers towards glucose electrochemical oxidation in alkaline medium

Aurélien Habrioux,Karine Servat,Thierry Girardeau,Philippe Guérin,Teko W. Napporn,K. Boniface Kokoh 한국물리학회 2011 Current Applied Physics Vol.11 No.5

The electrochemical activation of glucose was studied at the surface of gold particles prepared either by magnetron sputtering or water-in-oil microemulsion methods. At lower potentials smaller sputtered electrocatalysts (i.e. with Feret’s diameter lower than 5 nm) involved a remarkable activity, which was likely due to their electronic structures. It was suggested that the enhancement of the electrocatalytic performances at the surface of the electrodes composed of largest particles could be related to the formation of “sticking defects” in the nanomaterials.

Computed tomographic assessment of retrograde urohydropropulsion in male dogs and prediction of stone composition using hounsfield unit in dogs and cats

Aurélie Bruwier,Benjamin Godart,Laure Gatel,Dimitri Leperlier,Anne-Sophie Bedu 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.5

Background: Persistent uroliths after a cystotomy in dogs are a common cause of surgical failure. Objectives: This study examined the following: the success rate of retrograde urohydropropulsion in male dogs using non-enhanced computed tomography (CT), whether the CT mean beam attenuation values in Hounsfield Units (mHU) measured in vivo could predict the urolithiasis composition and whether the selected reconstruction kernel may influence the measured mHU. Methods: All dogs and cats that presented with lower urinary tract uroliths and had a non-enhanced CT preceding surgery were included. In male dogs, CT was performed after retrograde urohydropropulsion to detect the remaining urethral calculi. The percentage and location of persistent calculi were recorded. The images were reconstructed using three kernels, from smooth to ultrasharp, and the calculi mHU were measured. Results: Sixty-five patients were included in the study. The success rate of retrograde urohydropropulsion in the 45 male dogs was 55.6% and 86.7% at the first and second attempts, respectively. The predominant components of the calculi were cystine (20), struvite (15), calcium oxalate (8), and urate (7). The convolution kernel influenced the mHU values (p < 0.05). The difference in mHU regarding the calculus composition was better assessed using the smoother kernel. A mHU greater than 1,000 HU was predictive of calcium oxalate calculi. Conclusions: Non-enhanced CT is useful for controlling the success of retrograde urohydropropulsion. The mHU could allow a prediction of the calculus composition, particularly for calcium oxalate, which may help determine the therapeutic strategy.

THE INFLUENCE OF DESIGN ON LUXURY BRAND LOVE

Aurélie Hemonnet-Goujot,Pierre Valette-Florence 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

While product design is intrinsically linked to brand building and to the definition of luxury, consumers’ sensitivity to luxury products and to design is usually addressed separately. Yet, for optimal marketing-oriented decisions, they need to be brought together. Furthermore, while design is intrinsically linked to luxury, little research focused on its influence on the symbolic and the economic value of brands. This research specifically delves into the mechanisms behind how brand-level attitudes can be influenced by product-level sensitivity to product design. Building on the value theory, it investigates to what extent the product design enhances luxury brands value. Based on a data set collected on 125 individuals, a partial least square analysis was used. It contributes and extends literature on branding, design and luxury in three distinct ways. Firstly, this research distinguishes two antecedents of the product design that are the social and the individual drivers. Secondly, it reveals the mediating role of the product design between social and individual drivers, on one hand, and luxury brands symbolic value (through brand love and brand equity), on the other hand. Thirdly, it confirms the creation of economic value through the positive influence on willingness to pay a premium price. In terms of managerial implications, this study reveals the importance for luxury brands to develop sensory branding through product design. It especially points out the added-value of design for luxury brands’ equity, its role in fostering brand love and in increasing luxury brands turnover.

Hydrodynamic characteristics of activated carbon in air- and water-fluidized beds

Aurél Ujhidy,György Bucsky,Jenö Németh 한국화학공학회 2008 Korean Journal of Chemical Engineering Vol.25 No.5

The hydrodynamic characteristics of small hydrophobic activated carbon particles were determined in air flowing through both fixed and fluidized bed layers and water flowing through an inverse fluidized bed. Based on experimental data the Ergun-equation was corrected. A new relationship is proposed to predict the pressure drop in a fixed bed with gas flowing by using the minimum fluidizing velocity (umf) and particle terminal velocity (ut). Apparent density of oven-dried activated carbon increases with filling the internal pores by water. After the bed density reaches the density of water, the system switches from an inverse fluidized layer into the classical fluidized state. Finally, it has been demonstrated that the Reynolds number (Remf) at umf associated with the original Archimedes number (Ar) for gas-solid fluidized system and the modified Ar numbers characterizing the inverse fluidized beds lie on identical curves.

A global overview of enamel microabrasion for white spot lesions: a bibliometric review

Rocha Aurélio de Oliveira,Cardoso Karina,Goebel Michely Cristina,Santos Pablo Silveira,dos Anjos Lucas Menezes,Ribeiro Juliana Silva,Santana Carla Miranda,Cardoso Mariane 대한치과보존학회 2024 Restorative Dentistry & Endodontics Vol.49 No.3

This study aimed to identify and analyze articles on enamel microabrasion for the treatment of white spot lesions. A search was conducted on the Web of Science. The following parameters were recorded and analyzed: number of citations, year, journal, impact factor, study design, theme, country and continent, institution, authors, and keywords. Data was analyzed using VOSviewer software. The initial search resulted in 1,126 documents, of which 94 articles were included. The highest number of citations an article received was 65. The oldest article was published in 1975, and the most recent in 2023. The most frequent study design was case report (n = 42). Regarding the themes, it was observed that the main objective of the studies was to evaluate the clinical performance of enamel microabrasion (n = 75), primarily using Opalustre (Ultradent Products Inc., South Jordan, UT, USA) (n = 37) for treating white stains caused by dental fluorosis (n = 41). Most articles originated from Latin America (n = 31), mainly from Brazil (n = 26). The most frequent author was Sundfeld RH (n = 10). This study reveals research trends in the field of enamel microabrasion. The publications were mainly case reports/series using Opalustre for the removal of fluorosis stains.

Meeting the unmet: from traditional to cutting‑edge techniques for poly lactide and poly lactide‑co‑glycolide microparticle manufacturing

Stefano Giovagnoli,Aurélie Schoubben,Maurizio Ricci 한국약제학회 2019 Journal of Pharmaceutical Investigation Vol.49 No.4

Background Polylactides (PLA) and poly lactide-co-glycolides (PLGA) undoubtedly are among the major drivers in the pharmaceutical market. Their relevance in pharmaceutics and biomedicine is well established in light of their sustainability, safety, tunable biodegradability, and versatility. However, polymer degradability and plasticity can somehow restrain industrial developability of PLA and PLGA formulations, especially in the form of microparticles (MP). Area covered This review wants to deal with the known manufacturing issues of PLA/PLGA MP, debating the potential contribution of modern and cutting-edge manufacturing technologies to the solution of unmet production needs. Technological and regulatory aspects will be considered outlining the potential role of advanced manufacturing techniques in the advancement of PLA/PLGA MP production processes. Expert opinion The multifaceted complexity of PLA/PLGA MP manufacturing processes demands adequate standardization and updated guidelines covering the so far unmet industrialization requirements. Novel and evolving manufacturing technologies will surely support the future development of bench-to-production plant transfer for such products. Careful evaluation of production costs is demanded in order to ensure process sustainability and patient’s outreach.

Fast response time of micropixels with in-plane switching of positive liquid crystals using crossed patterned electrodes

Clément Abélard,Aurélien Suhm,Benoit Racine,Umberto Rossini,François Templier 한국정보디스플레이학회 2019 Journal of information display Vol.20 No.3

Demonstrated herein is a fast in-plane switching (IPS) cell with positive dielectric anisotropy liquid crystals using crossed patterned electrodes in three different conditions. The ineffectiveness of one of these three structures due to the ‘Faraday cage’ effect was shown. With another structure, a fast response time was also shown to be impossible to achieve due to several contrast issues. In the third structure, a fast response time was achieved due to a combination of high-driving and crossed patterned electrodes allowing fast turn-off. Two of the three structures was manufactured. With the first one, an experiment confirmed the ‘Faraday cage’ effect. In the second structure, a response time four to eight times faster than the conventional IPS mode was experimentally demonstrated using two different kinds of liquid crystal.

Consolidation of a Learned Skill Correlates with Dopamine SPECT Uptake in Early Parkinson’s Disease

Nicolas Nicastro,Aurélie L. Manuel,Valentina Garibotto,Pierre R. Burkhard,Armin Schnider 대한신경과학회 2018 Journal of Clinical Neurology Vol.14 No.4

Background and Purpose Basal ganglia play a pivotal role in procedural memory. However, the correlation between skill learning and striatal 123I-ioflupane uptake in Parkinson’s disease (PD) has not been reported previously. Our objective was to determine whether visuomotor skill learning is associated with striatal 123I-ioflupane uptake in early PD. Methods We designed a case–control study to assess learning and consolidation of a visuomotor learning task (mirrored drawing of star-shaped figures) performed on two consecutive days by early-PD patients (disease duration <2 years) and age-matched healthy subjects. Outcomes were the error rate and time per trial, as well as performance indices to assess the relative improvement on the first day (learning) and the retention on the second day (consolidation). For PD patients, we evaluated the correlation of skill learning with semiquantitative 123I-ioflupane uptake. Results We included 9 PD patients and 10 control subjects with the same baseline characteristics (age, male/female ratio, educational level, Mini Mental State Examination score, and Hospital Anxiety and Depression Scale score, all p>0.18) other than the score on part III of the Movement Disorders Society Unified Parkinson’s Disease Rating Scale, which was higher in the PD patients (mean±SD: 15.0±10.4 vs. 1.3±1.1, p<0.001). The learning indices were the same in the two groups (p>0.5), whereas PD patients showed a lower consolidation index for the time per trial (p=0.009). Moreover, this performance was correlated with uptake in the right caudate nucleus (Spearman’s rho=0.82, p=0.007) and the right striatum (Spearman’s rho=0.67, p=0.049), including when multiple linear regression adjusting for the levodopa equivalent daily dose was performed (p=0.005 for the caudate nucleus and p=0.024 for the striatum). Conclusions This study provides evidence of a correlation between procedural memory impairment and striatal dopaminergic dysfunction in early PD.

Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy

Taveau Nicolas,Cubizolle Aurélie,Guillou Laurent,Pinquier Nicolas,Moine Espérance,Cia David,Kalatzis Vasiliki,Vercauteren Joseph,Durand Thierry,Crauste Céline,Brabet Philippe 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

Environmental light has deleterious effects on the outer retina in human retinopathies, such as ABCA4-related Stargardt’s disease and dry age-related macular degeneration. These effects involve carbonyl and oxidative stress, which contribute to retinal cell death and vision loss. Here, we used an albino Abca4−/− mouse model, the outer retina of which shows susceptibility to acute photodamage, to test the protective efficacy of a new polyunsaturated fatty acid lipophenol derivative. Anatomical and functional analyses demonstrated that a single intravenous injection of isopropyl-phloroglucinol-DHA, termed IP-DHA, dose-dependently decreased light-induced photoreceptor degeneration and preserved visual sensitivity. This protective effect persisted for 3 months. IP-DHA did not affect the kinetics of the visual cycle in vivo or the activity of the RPE65 isomerase in vitro. Moreover, IP-DHA administered by oral gavage showed significant protection of photoreceptors against acute light damage. In conclusion, short-term tests in Abca4-deficient mice, following single-dose administration and light exposure, identify IP-DHA as a therapeutic agent for the prevention of retinal degeneration.

The Synergistic Effect of Polymer Composition, Solvent Volatility, and Collector Distance on Pullulan and PVA Fiber Production by Rotary Jet Spinning

Leonardo de Souza,Alex Carvalho Alavarse,Marco Aurélio da Vinci,Jean-Jacques Bonvent 한국섬유공학회 2021 Fibers and polymers Vol.22 No.4

Rotary jet spinning (RJS) method is showing a growing interest as one of the most efficient techniques for micro/nanofibers production. This paper reports the investigation on the influence of the pullulan/PVA blend solution composition,the solvent volatility and spinneret-collector distance on the fiber’s diameters produced by RJS technique. To optimize thenumber of required experiments for a complete evaluation, a central composite rotatable design (CCRD) and responsesurface methodology (RSM) were applied by means of Design Expert software. The fibrous mats morphology and thermalstability were analyzed as a function of the different parameters investigated. It was found a strong dependence of the fiberdiameter on the blend composition and DMSO content, which could be explained mainly by the rheological properties of thepolymer solution. The Response Surface Methodology analysis shows that the complex influence of the independentvariables on the fiber’s diameter could be fitted by an empirical model.