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RISS 인기검색어
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- 저자 : Arthanareeswaran Karunambigai (검색결과 1 건)
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Rahul Sharma,Arthanareeswaran Karunambigai,Somlee Gupta,Neelakantan Arumugam 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.4
Acmella ciliata (HBK) Cass. (basionym: Spilanthes ciliata HBK) is an herb of high medicinal value. Spilanthol, the prime N-alkamide in A. ciliata, is used as an active ingredient in several anti-ageing herbal tonics and in mouth washes. Here we describe quantification of spilanthol, phenolics, flavonoid and antioxidant activity in the methanol extracts prepared from flower, leaf, root and stem of the plant. HPLC of the sample extracts revealed that spilanthol was found to be maximum in flowers (18.44 mg/g), as compared to other parts of the plant as well as several of other Acmella (syn: Spilanthes) species. Estimation of phenolics and flavonoids in the extract by spectrophotometry with their values expressed respectively as equivalence of gallic acid (GAE) and quercetin (QE), revealed that phenolics content was highest in the flower extract (5.58 mg GAE/g), whereas, flavonoid content was found maximum in the leaf extract (31.65 mg QE/g). Antioxidant activity of the extract remained proportional to phenolic content of the extract. Flower extract further showed highest free radical scavenging activity in DPPH and ABTS assays, as compared to the extracts from other parts of the plant. Pearson’s correlation for antioxidant activity with respect to the phenolic and flavonoid content turned out to be positive. To the best of our knowledge this is the first report on quantification of the three secondary metabolites considered here and the antioxidant activity in the methanol extract prepared from different parts of A. cilitata.
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