http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Andres Rodríguez-Galvan (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Adsorption and Self-Assembly of Anticancer Antibiotic Doxorubicin on Single-Walled Carbon Nanotubes
Andres Rodríguez-Galvan,Oscar Amelines-Sarria,Margarita Rivera,Maria del Pilar Carreon-Castro,Vladimir A. Basiuk 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.4
We performed a combined experimental and theoretical study of the conjugates obtained from single-walled carbon nanotubes and anticancer antibiotic doxorubicin (DOX). Atomic force microscopy (AFM) imaging at lower magnification revealed, extended regions of single-walled carbon nanotubes (SWNTS) fully covered with DOX adsorbed molecules, along with some bare parts without the adsorbed drug, thus suggesting that the DOX adsorption is a cooperative process. Ambient atmosphere scanning tunneling microscopy (STM) at higher resolutions found that individual SWNTs-DOX conjugates exhibit a periodic texture, whose most important morphological feature is alternating depressions and protrusions along the nanotube. Based on the images and profiles measured, we suggest that doxorubicin molecules self-assemble on SWNTs sidewall according to a helical pattern, in which their tetracyclic fragments are turned with respect to the nanotube axis by about 50°. To provide an additional insight into the structure of noncovalent SWNTs-DOX conjugates, we employed density functional theory (DFT) calculations with three long-range corrected functionals: M05-2X, wB97X-D and LCBLYP, of which M05-2X yielded the most realistic results in terms of geometries and energies.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
