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        Design and 3D-printing of titanium bone implants: brief review of approach and clinical cases

        Vladimir V. Popov Jr.,Gary Muller-Kamskii,Aleksey Kovalevsky,Georgy Dzhenzhera,Evgeny Strokin,Anastasia Kolomiets,Jean Ramon 대한의용생체공학회 2018 Biomedical Engineering Letters (BMEL) Vol.8 No.4

        Additive manufacturing (AM) is an alternative metal fabrication technology. The outstanding advantage of AM (3Dprinting,direct manufacturing), is the ability to form shapes that cannot be formed with any other traditional technology. 3D-printing began as a new method of prototyping in plastics. Nowadays, AM in metals allows to realize not only netshapegeometry, but also high fatigue strength and corrosion resistant parts. This success of AM in metals enables newapplications of the technology in important fields, such as production of medical implants. The 3D-printing of medicalimplants is an extremely rapidly developing application. The success of this development lies in the fact that patientspecificimplants can promote patient recovery, as often it is the only alternative to amputation. The production of AMimplants provides a relatively fast and effective solution for complex surgical cases. However, there are still numerouschallenging open issues in medical 3D-printing. The goal of the current research review is to explain the whole technologicaland design chain of bio-medical bone implant production from the computed tomography that is performed by thesurgeon, to conversion to a computer aided drawing file, to production of implants, including the necessary post-processingprocedures and certification. The current work presents examples that were produced by joint work of Polygon MedicalEngineering, Russia and by TechMed, the AM Center of Israel Institute of Metals. Polygon provided 3D-planning and 3Dmodellingspecifically for the implants production. TechMed were in charge of the optimization of models and theymanufactured the implants by Electron-Beam Melting (EBM ), using an Arcam EBM A2X machine.

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        Additive manufacturing to veterinary practice: recovery of bony defects after the osteosarcoma resection in canines

        Vladimir V. Popov Jr.,Gary Muller-Kamskii,Alexander Katz-Demyanetz,Aleksey Kovalevsky,Stas Usov,Dmitrii Trofi mcow,Georgy Dzhenzhera,Andrey Koptyug 대한의용생체공학회 2019 Biomedical Engineering Letters (BMEL) Vol.9 No.1

        The paper outlines the achievements and challenges in the additive manufacturing (AM) application to veterinary practice. The state-of-the-art in AM application to the veterinary surgery is presented, with the focus of AM for patient-specifi cimplants manufacturing. It also provides critical discussion on some of the potential issues design and technology shouldovercome for wider and more eff ective implementation of additively manufactured parts in veterinary practices. Most of thediscussions in present paper are related to the metallic implants, manufactured in this case using so-called powder bed additivemanufacturing (PB-AM) in titanium alloy Ti–6AL–4V, and to the corresponding process of their design, manufacturing andimplementation in veterinary surgery. Procedures of the implant design and individualization for veterinary surgery are illustratedbasing on the four performed surgery cases with dog patients. Results of the replacement surgery in dogs indicate thatindividualized additively manufactured metallic implants signifi cantly increase chances for successful recovery process, andAM techniques present a viable alternative to amputation in a large number of veterinary cases. The same time overcomingchallenges of implant individualization in veterinary practice signifi cantly contributes to the knowledge directly relevant tothe modern medical practice. An experience from veterinary cases where organ-preserving surgery with 3D-printed patientspecific implants is performed provides a unique opportunity for future development of better human implants.

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