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      저자 : 최동욱(Dung Wook Choi) (검색결과 1 건)
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      • KCI등재후보

        간세포암 절제술 457례의 임상결과

        임진호(Jin Ho Yim),김상범(Sang Bum Kim),조응호(Eung Ho Cho),최동욱(Dung Wook Choi) 한국간담췌외과학회 2009 한국간담췌외과학회지 Vol.13 No.3

        Background & Purpose : This purpose of this study was to determine the prognostic factors for hepatocellular carcinoma (HCC) in patients who received curative hepatectomies at our institution. Patient and Method : A retrospective analysis was performed on 457 patients who had undergone hepatectomies between Mar 1987 and Feb 2008 for HCC at the Korea Cancer Center Hospital, Seoul, Korea. The number of males enrolled in the study was 366 and the numbr of fenales enrolled was 91. The mean age of the patients was 52.8 years old. Hepatitis B virus-related disease was the most frequent etiology (335/457 patients). Two hundred nine(209) patients had liver cirrhosis, and 93.9% of patients were classified in Child-Pugh Class A. Results : The complication rate was 30.6%(140/457) and the operative mortality was 1.5%(7/457). Reoperation was performed in 7 complicated patients. Five-and 10-year overall survival rates of the patients were 57.7% and 41.8% respectively. Poor prognostic factors of overall survival were Child B class, Edmonson-Steiner histologic grade 3 or 4, tumor vascular invasion, and postoperative complications. Five-and 10-year disease-free survival rates were 42.7% and 32.5%, respectively. Poor prognostic factors for disease free survival included the following an Edmonson-Steiner histologic grade of 3 or 4, tumor vascular invasion, and postoperative complications. Conclusion : Postoperative complication is independently a poor prognostic factor for overall and disease free survival in our study. We suggest that special care is needed while performing hepatic resections for the treatment of HCC in order to reduce postoperative complications.

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