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한국 여성에서 sALP(Skeletal Alkaline Phosphatase) 참조치 설정에 관한 연구
천준홍 ( Jun Hong Cheon ),최우준 ( Woo Joon Choi ),문형호 ( Hyoung Ho Moon ),정윤영 ( Yoon Young Chung ),이승관 ( Seung Gwan Lee ) 대한임상검사과학회 1998 대한임상검사과학회지(KJCLS) Vol.30 No.2
sALP(Skeletal Alkaline Phosphatase), a tetrameric glycoprotein is localized in the plasma membrane of the Osteoblast and is released into the circulation as a dimer. Serum level of sALP are believed to reflect the metabolic state of osteoblast. We measured serum sALP with a immunoradiometric assay(IRMA} in a large sample of healthy korean women. In this study we have analyzed reference values of sALP obtained from some healthy korean women by means of AIC(Akaike’s Information Criterion) method. Following results were obtained. 1. In total group, it had showen that the optimal model for normal distribution was the power function [f(x}=ln(x)] with reference range of 5 - 31 μ g/L. 2. Power function were the predominant one in all age groups, with reference ranges of 5 - 18μg/L, 5 - 23μg/L, 6 - 32μg/L, 6 - 30μg/L in 30s, 40s, 50s, and 60s of female.