"질리도록 먹어서 칼로리 줄여라"

이정윤,Lee, Jeong-Yun 한국과학기술단체총연합회 2003 과학과 기술 Vol.36 No.6

Short-term Effect of Botulinum Toxin Injection on the Surface EMG of Masticatory Muscles and Jaw Function

이정윤,박희경,정진우,Lee, Jeong-Yun,Park, Hee-Kyung,Chung, Jin-Woo Korean Academy of Orofacial Pain and Oral Medicine 2006 Journal of Oral Medicine and Pain Vol.31 No.1

Botulinum toxin injection has been used in the masticatory muscle area as an effective treatment method of various movement disorders and facial contouring, but its effects on jaw function have not been evaluated. The aims of this study were to evaluate the effects of botulinum toxin type A injection into the masseter muscle on the EMG activities of masseter and anterior temporal muscles, and the limitation of jaw function. Fourteen healthy subjects were recruited. Five subjects were injected with 80 units of botulinum toxin type A(Dysport, Ipsen, Wrexham, UK) into each side of masseter muscle, and nine subjects were injected with saline into the same site as the botulinum toxin group. The surface EMG activities at maximum voluntary contraction of masseter and anterior temporal muscles were recorded before, 1 week, 2 weeks, and 3 weeks after injection. Presence of jaw functional limitations in each subject was investigated using Korean version of Jaw Functional Limitation Scale(JFLS) questionnaire. The masseter muscle EMG was gradually decreased in the botulinum toxin group comparing with that of the control group(p<0.001), but the anterior temporal muscle EMG did not show significant changes. There was significant increases in the mastication (p<0.01), and global jaw limitation(p<0.05) subscales of JFLS at 1 week after injection, but no significant changes in the other subscales including opening, and verbal and emotional expression during the recording periods. Our results suggest that botulinum toxin injection into masseter muscle can affect modest limitation in mastication function at 1 week after injection but recovered to the baseline until 3 weeks after injection. The EMG activity of masseter muscle had been gradually decreased until 3 weeks after botulinum toxin injection but the anterior temporal muscle did not show any significant changes.

질량감도 해석에 의한 2차원 연속계의 진동특성에 관한 연구

이정윤,박호,오재응,Lee, Jung-Yoon,Park, Ho,Oh, Jae-Eung 대한기계학회 1990 대한기계학회논문집 Vol.14 No.2

Techniques which are able to predict and control dynamic characteristics, not affecting the vibrational characteristics on the modification of structural design, are being studied. As one of these techniques, experimental modal analysis is widely applied by many researchers. In this study, modal analysis is performed using transfer matrix method by a macro computer. The developed program would estimate the structural modal parameters precisely, and the validity of this program is certified by comparing with the experimental results of .GAMMA A. structure. Estimated modal parameters(natural frequency, vibrational mode, equivalent mass, etc.) are in accord with the experimental results. Also, the optimal location of the additive mass is determined by the evaluation of the vibrational mode and the equivalent mass. The relation between the additive mass and the equivalent mass is specified, and we come to know that the ratio of equivalent mass to additive mass alter linearly within the range of 20%.

Effects of red ginseng oil(KGC11 o) on testosterone-propionate-induced benign prostatic hyperplasia

이정윤,김소혁,김석호,김종한,배봉석,구기방,Seung Ho So,Jeongmin Lee,Yoo-Hyun Lee 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.3

Benign prostatic hyperplasia (BPH) is a disease characterized by abnormal proliferation ofthe prostate, which occurs frequently in middle-aged men. In this study, we report the effect of redginseng oil (KGC11o) on BPH. Methods: The BPH-induced Sprague-Dawley rats were divided into seven groups: control, BPH, KGC11o25, 50, 100, 200, and finasteride groups. KGC11o and finasteride were administered for 8 weeks. The BPHbiomarkers, DHT, 5AR1, and 5AR2, androgen receptor, prostate-specific antigen (PSA), Bax, Bcl-2, andTGF-b were determined in the serum and prostate tissue. The cell viability after KGC11o treatment wasdetermined using BPH-1 cells, and, androgen receptor, Bax, Bcl-2, and TGF-b were confirmed by westernblotting. Results: In the in vivo study, administration of KGC11o reduced prostate weight by 18%, suppressed DHT(up to 22%) and 5AR2 (up to 12%) levels from administration of 100 mg/kg KGC11o (P < 0.05). PSA wassignificantly downregulated dose-dependently from at the concentration of 50 mg/kg KGC11o (P < 0.05). BPH-1 cell viability significantly reduced through the treatment with KGC11o. In vitro and vivo, AR, Bcl-2TGF-b levels reduced significantly but Bax was increased (P < 0.05). Conclusion: These results suggest that KGC11o may inhibit the development of BPH by significantlyreducing the levels of BPH biomarkers via 5ARI, anti-androgenic effect, and anti-proliferation effect,serving as a potential functional food for treating BPH.

대표공종의 선정을 통한 약식 기성 산정 방법에 관한 연구 - 자연형 하천공사를 중심으로

이정윤,우성권,Lee, Jeong-Yoon,Woo, Sung-Kwon 한국건설관리학회 2010 한국건설관리학회 논문집 Vol.11 No.1

내역서를 기반으로 하는 국내 공공공사의 기성 산정 방법은 작업진도의 산출과 무관한 기성고 산정과 많은 양의 서류작성과 복잡한 절차 등의 많은 문제점이 있다. 국가계약법에서 정식과 약식 기성 산정 방법으로 구분되며, 이중에서 약식 기성 산정 방법은 절차와 신청서류를 간소화하여 이와 같은 문제점을 상당 부분 해결 가능하지만 이의 활용이 미비한 실정이다. 본 연구에서는 작업분류체계의 수립과 이를 기반으로 선정된 대표공종의 진도율을 이용하여 기성을 산정하는 방법을 제안하였으며, 자연형 하천공사의 실적공사 데이터를 수집하여 이를 적용을 통한 국내 공공공사의 기성 산정 방법과의 비교를 통해, 기성 산정을 위한 관리항목의 감소로 인한 업무 부담의 감소와 빠르고 효과적인 기성 산정을 통한 업무효율의 증가 등 그 효율성을 검증하였다. 이러한 기성 산정 방법론의 도입은 기존 방법의 문제점 해결을 통한 업무효율의 증가뿐만 아니라 향후 공공공사의 사업관리에 있어서 그 효율성이 검증된 공정-공사비 통합관리의 기반을 다지는 데 있어 큰 의미가 있다. In domestic public works, there are several problems in the measurement of payments based on the bill of quantity, which doesn't match with the activity progress rate, heavy paper works and complicated procedures. It can be classified formal and simplified method. By using the simplified method, it can be solved many problems by summarizing the procedure, but is not generally used. This paper proposes a payment method by progress measurement for specified activity based on WBS(Work Breakdown Structure) verifying efficiency which reduced cost account and advanced work on payment compare to method of domestic public works using the data about construction of eco-river. This method will be an important contribution on being a base for cost-schedule integrated management which were verified and also improving efficiency on measuring payment.

Factors Related to Patients' Satisfaction Level of Treatment Outcome of Oral Malodor

이정윤,고홍섭,김영구,정성창,이승우,Lee, Jeong-Yun,Kho, Hong-Seop,Kim, Young-Ku,Chung, Sung-Chang,Lee, Sung-Woo The Korean Academy of Orofacial Pain and Oral Medi 2001 Journal of Oral Medicine and Pain Vol.26 No.1

본 연구에서는 환자들에 의해 구취와 관련이 있다고 일반적으로 믿어지고 있는 여러 요인들이 치료 후의 환자의 만족도에 미치는 영향에 대해 알아봄으로써 환자의 만족도의 예후를 판단할 수 있는 자료를 마련하고자 하였다. 서울대학교 치과병원 구강진단과에 구취를 주소로 내원한 환자 194명을 대상으로 설문지를 이용하여 구취와 관련성이 있는 것으로 알려져 있는 항목들을 조사하였다. 조사 항목으로는 1) 본인확인가능여부, 2) 타인확인가능 여부, 3) 구취의 기간, 4) 구취의 빈도, 5) 축농증, 6) 비염, 7) 코수술 병력, 8) 콧물이 목뒤로 넘어감, 9) 코막힘, 10) 비호흡 곤란, 11) 구강건조감, 12) 편도선부종, 13) 가래, 14) 신물의 역류, 15) 소화불량, 16) 흡연여부가 포함되었다. 구취의 평가는 portable sulfide monitor인 $Halimeter^{(R)}$(Interscan Co., Chatsworth, CA, USA)를 이용하여 치료 전, 후에 각각 측정하였고, 혀배면의 세정, 치면 세균막 조절, 0.25% $ZnCl_2$ 양치액의 사용을 내용으로 하는 구취의 치료를 시행한 뒤 자신의 구취개선정도에 대해 %로 질문하여 치료 후 만족도를 조사하였다. 각 조사 항목과 치료 후 만족도 사이의 상관관계 및 실제 $Halimeter^{(R)}$ 수치의 개선정도와 만족도 사이의 상관관계를 분석하였으며, Symptom Checklist - 90 Revised(SCL-90R)의 분석결과에 따라 환자를 두 그룹으로 분류하고 두 그룹 사이의 치료 후 만족도의 차이를 조사한 결과 다음과 같은 결론을 얻었다. 1. 본인 및 타인 확인가능여부, 구취가 항상 나는지 여부, 구취의 기간, 축농증, 비염, 코수술 병력, 코막힘, 비호흡 곤란, 콧물이 목뒤로 넘어감, 흡연여부에 따른 치료 후 만족도의 유의한 차이는 없었다. 2. 신물의 역류(p=0.003), 소화불량(p=0.007), 구강건조감(p=0.016), 편도선 부종(p=0.018), 가래(p=0.033)에 따른 치료 후 만족도는 통계적으로 유의한 수준의 차이를 보였다. 3. $Halimeter^{(R)}$ 수치의 개선정도와 만족도 사이의 유의한 상관관계는 관찰되지 않았다(r=0.092, p=0.201).

풍향계 - 탈핵 에너지 전환 시대의 대한민국 원자력 - 핵심은 안전

이정윤,Lee, Jeong-Yun 한국원자력산업회의 2017 원자력산업 Vol.37 No.7

구강건조증 증상 평가를 위한 설문지의 신뢰도에 관한 연구

이정윤,이영옥,고홍섭,Lee, Jeong-Yun,Lee, Young-Ok,Kho, Hong-Seop 대한안면통증구강내과학회 2005 Journal of Oral Medicine and Pain Vol.30 No.4

Xerostomia is defined as a subjective complaint of dry mouth that may be perceived when there is insufficient mucosal wetting. However, the diagnosis and treatment of xerostomia is not that simple because of the fact that the subjective awareness of dry mouth is not always correlated with a diminution in the flow of saliva and there is always a difference between individuals in salivary flow rates needed for normal oral function. In the present study, the aim was to develop a questionnaire to evaluate the dry mouth symptoms and to analyze its reliability and usability as a diagnostic and analytic tool for xerostomia. The questionnaire which consists of 6 Visual Analogue Scale(VAS) type questions to evaluate the subjective oral dryness and 4 questions to evaluate behavior to avoid oral dryness was developed and administered twice with 1 week's interval to the healthy 88 young adults without dry mouth symptoms(44 males and 44 females; mean age was $25.6{\pm}3.1$ years in male and $24.3{\pm}2.1$ years in female). The results were as follows. 1 The intraclass correlation coefficients of 6 questions to evaluate the subjective oral dryness were as significantly high as 0.767 for the degree of oral dryness at other times of the day, 0.850 for the amount of saliva in the mouth, and 0.791 for the degree of effect on daily life due to oral dryness and as high as 0.563 for the degree of oral dryness at night or on awakening, 0.674 for the degree of oral dryness during eating, and 0.641 for the degree of difficulty in swallowing foods. 2. Cronbach's alpha value of 6 questions was 0.982. It can be concluded that the series of questions to evaluate the subjective oral dryness has high internal consistency. 3. Cohen's kappa values of 4 questions to evaluate behavior to relieve oral dryness were as significantly high as 0.850 for the frequency of keeping a glass of water at the bedside and as high as 0.506 the frequency of awakening during sleeping due to oral dryness, 0.419 for the frequency of sipping liquids to aid in eating dry foods, and 0.407 for the frequency of using a candy or chewing gum due to oral dryness. From the results, it can be concluded that the questionnaire consisting of 6 VAS type questions to evaluate the subjective oral dryness and 4 questions to evaluate behavior to relieve oral dryness has reliability of good to excellent level, and that the series of 6 VAS type questions has significantly high internal consistency to evaluate the subjective oral dryness.

시각적 공간분석학 기법을 활용한 지역별 수출화물 발생패턴 유형화

이정윤,안재성,Lee, Jung-Yoon,Ahn, Jae-Seong 한국공간정보학회 2007 한국공간정보학회지 Vol.15 No.3

시각적 공간분석학은 인간의 공간인지 및 분석 능력을 최대한 발휘할 수 있는 다양한 시각화 도구를 개발함으로써 복잡한 시공간 데이터를 효율적으로 분석하는 학문으로, 궁극적으로는 인간의 추론능력과 시각적 분석도구의 효과적인 융합을 목적으로 한다. 시각적 공간분석학은 최적의 의사결정지원 도구를 개발하는 방법론으로 그 활용 범위가 매우 넓은데, 최근에는 지리적 시각화의 연구 전통을 계승하여 새로운 시각화 도구를 개발하고 다양한 분석을 통해 그 유용성을 확인하는 연구들이 시작되고 있다. 본 연구는 최근에 제안된 시각화 도구인 T 산포도와 전산분석법을 통합하여 우리나라 지역별 수출화물 발생패턴을 7개 유형으로 분석함으로써, 향후 공간의사결정 지원과정에서 시각적 공간분석학의 다양한 활용 가능성을 제시해주고 있다. Geovisual analytics is the new research area that looks fur the way to enable a truly synergetic work of human and visualization tool in analyzing spatio-temporal data. The research challenge for geovisual analytics is developing new geovisualization tools and enhancing human capabilities to analyse, envision, and reason a lot of spatio-temporal changes. With this research area, geovisual analytics is expected to be a new methodology for developing spatial decision support tools. This research is to integrate T scatter plot with computational method to classify the several patterns of the regional fright generation in Korea. The result of this work shows the capabilities provided by geovisual analytics to support spatial decision making.

절연유중 부분방전 검출을 위한 안테나의 최적 설계

이정윤,조향은,박대원,길경석,오재근,Lee, Jung-Yoon,Jo, Hyang-Eun,Park, Dae-Won,Kil, Gyung-Suk,Oh, Jae-Geun 한국전기전자재료학회 2013 전기전자재료학회논문지 Vol.26 No.4

This paper dealt with the radiated electromagnetic wave detection of partial discharge (PD) in oil for insulation diagnostics of oil-immersed transformers. Three types of electrode system were fabricated to simulate the insulation defects that could occur in oil-immersed transformers. Frequency components of radiated electromagnetic wave in oil was measured by broadband bi-conical antennas of 300 MHz~2 GHz and a spectrum analyzer of 9 kHz~3 GHz. Frequency component of electromagnetic waves from PD in oil were highly distributed at 500 MHz. From the result, a narrow-band monopole antenna with the center frequency of 500 MHz was fabricated. We could detect PD signal in insulation oil without an influence of external noise by a measurement system which consists of the prototype monopole antenna, a LNA (Low Noise Amplifier), an oscilloscope and a spectrum analyzer.