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권지윤(Ji Yoon Kwon),김건하(Gun-Ha Kim),은소희(SoHee Eun),은백린(Baik-Lin Eun),변정혜(Jung Hye Byeon) 대한소아신경학회 2017 대한소아신경학회지 Vol.25 No.3
Purpose: Among syndromes of idiopathic occipital lobe epilepsy there are Panayioto poulos syndrome (PS) and idiopathic childhood occipital epilepsy of Gastaut (ICOE-G). However, the classification of epilepsy syndrome is difficult to diagnose at the first seizure because of varying characteristics. We analyzed the different clinical charac teristics and prognostic factors of idiopathic occipital lobe epilepsy. Methods: Forty-three patients who had at least two unprovoked seizures, no abnor malities on magnetic resonance imaging, no known etiology of seizure, and mainly occipital spikes on electroencephalography were retrospectively enrolled at the Korea University Medical Center. A good prognosis was defined as being seizure-free and taking two or less drugs for 1 year. Results: Among all patients, the proportion of PS was 44.2%, ICOE-G was 7.0% and unclassified group was 48.8%. The age at seizure onset was 4.5±2.6 years (mean±SD) in the PS group, and 8.3±2.1 years in the ICOE-G group. The follow-up duration was 10.8±6.0 years. The percentage that the initial diagnosis had not been changed was 66.7% in the PS group and 100% in the ICOE-G group. Among other related symp toms only emesis (P<0.001) and visual symptoms (P=0.007) had varying characteri stics between the PS and ICOE-G groups. Patients with PS had a better prognosis than those with ICOE-G or unclassified group (odds ratio [OR]=58.8). Patients with 1 more autonomic symptoms had a worse prognosis (OR=3.8). Conclusion: This study showed that only symptoms of emesis and visual symptoms can differentiate between PS and ICOE-G. More autonomic symptoms were associated with worse prognosis in childhood occipital lobe epilepsy.
KCI
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