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성상윤 외 중앙대학교 의과대학 의학연구소 2004 中央醫大誌 Vol.29 No.1·2
Epidemiological studies suggests an increasing incidence of male infertility. Our understanding of the importance of environmental, genetic and occupational factors on sperm count and fertility is constrained by the extreme variation in sperm count. The relative importance of the various factors and the pathways via which they affect sperm count are discussed. The possible role of other environmental factors commonly supposed to affect sperm count (exposure to pesticides or endocrine disruptors) is discussed, although the evidence for a major influence of such factors is lacking. Intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of male infertility. But futher research into the causes and specific treatment of idiopathic male factor infertility is needed.