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신종 인플루엔자 A(HIN1) 환자에서 인후부 바이러스 배출 변화
황일웅 ( Hwang Il Ung ),이희경 ( Lee Hee Kyeong ),서미영 ( Seo Hi Young ),김재표 ( Kim Jae Pyo ),서유빈 ( Seo Yu Bin ) 국군의무사령부 2010 대한군진의학학술지 Vol.41 No.1
Objective: To assess the duration of Viral shedding in the patients infected with pandemic influenza A(H1N1) virus Method: 33 patients who was confirmed as Pandemic influeza A(H1N1) infection with RT-PCR were followed to find how long they could shed the virus from throats. Pharyngeal swabs were taken from each patient on the day 5, 7, 10 after onset of symptoms. and tested by PCR. Results: mean age of patients was 21.5 years. Fever and cough were the most common symptoms. Of 33, 9 were prescribed Olseltamivir, and 24 were not. The former group showed rapid drop of virus shedding after day 5 but no statistical significance was found d/t small number of cases. 21 cases(63.6%) were positive on day 5, 6 cases(18.2%) on day 7, and 0 case(0%) on day 10 Conclusions: In some cases, pandemic influenza A(H1N1) virus is shedding from the patients' throat and may have infectivity even on the 7th day after symptom . Further reseach including viral culture is needed to assess accurate shedding duration of live virus.