영아 패혈증 치료에 있어서의 Fosfomycin Sodium의 사용 1례

문명성,김경신,이근수 최신의학사 1983 最新醫學 Vol.26 No.2

실리콘 유방 보형물 파열로 인한 폐 혈전색전증 1례

문명성,리원연,용석중,김상하,이석정,이지호,박순민,유이슬,장민석 대한내과학회 2022 대한내과학회 추계학술발표논문집 Vol.2022 No.2

2 stage LC 회로를 이용한 LED Back Light Unit Driver 회로에서의 전압, 전류 안정화 방법

문명성(Myoung-Sung Moon),이중희(Jung-Hee Lee),성광수(Gwang-Soo Sung),장자순(Ja-Soon Jang) 한국조명·전기설비학회 2010 한국조명·전기설비학회 학술대회논문집 Vol.2010 No.5월

In order to realize low power consumption and the uniformly efficiency of LED BLU (Back-Light Unit) system, new circuits with 2 stage L-C (inductor-capacitance) circuits have been proposed. From the simulation results based on our proposed model, the ripple power of the L-C regulation-embedded BLU circuit shows a dramatic reduction by more than 89.3 % as compared to the normal BLU (without L-C circuits), indicating that the proposed compensating-circuit is very promising for the realization of high-efficiency BLU circuits.

RLC regulation circuit과 snubber circuit을 이용한 LED Back Light Unit Driver 회로에서의 전압, 전류 안정화 방법

문명성(Myoung-Sung Moon),권오순(O-Soon Kwon),김범수(Bum-Soo Kim),이중희(Jung-Hee Lee),장자순(Ja-Soon Jang) 한국조명·전기설비학회 2011 한국조명·전기설비학회 학술대회논문집 Vol.2011 No.5월

In order to realize low power consumption, system safety and the stable luminance uniformity of LED BLU (Back-Light Unit) system, new circuits with RLC (resistance-inductor-capacitance) regulation and snubber circuits have been proposed. From the simulation and experiment results based on our proposed model, the ripple power of the RLC regulation-embedded BLU circuit shows a dramatic reduction by more than 94.3 % as compared to the normal BLU and the overshoot voltage of the snubber circuit-embedded BLU circuit shows a dramatic reduction by more than 90.0 % as compared to the normal BLU, indicating that the proposed compensating-circuit is very promising for the realization of high-electrical efficiency BLU circuits.

청소년에서 우울 및 불안 증상과 수면 곤란의 성별에 따른 차별적 관련성

김은진,강수경,문명성,임세원,오강섭,Kim, Eun-Jin,Kang, Su-Gyeong,Moon, Myeong-Sung,Lim, Se-Won,Oh, Kang-Seob 한국정신신체의학회 2010 정신신체의학 Vol.18 No.2

연구목적 청소년에서 성별에 따른 불안, 우울과 수면 장애의 유병율을 조사하고 우울, 불안과 수면 곤란의 관련성을 성별에 따라 분석하고자 한다. 방 법 서울시 마포구 내 7개 중학교의 1학년 학생 1,422명을 대상으로 자가 보고 질문지인 Children's Depression Inventory(CDI), Beck Anxiety Inventory(BAI), Pittsburgh Sleep Quality Index(PSQI)를 실시하였다. CDI, BAI, 그리고 PSQI는 각각 다음과 같이 분류되었다 : $\leq$21, 22-25, 26-28, 그리고 $\geq$29 ; $\leq$21, 22-26, 27-31, 그리고 $\geq$32 ; $\geq$5, <5. 각각의 cut-off 점수는 CDI 22, BAI 22 그리고 PSQI는 5점 이었다. 두 군간 연속 변수 비교에는 독립 t-검정, 비 연속변수 비교에는 $\chi^2$-검정, 불안과 우울 증상이 수면 곤란에 미치는 영향은 로지스틱 회귀분석을 이용하였다. 결 과 여학생에서 평균 CDI 점수($12.52{\pm}8.32$ vs. $10.39{\pm}7.52$ ; p=0.003), BAI($7.77{\pm}7.9$ vs. $9.84{\pm}9.044$ ; p<0.001) 그리고 PSQI($4.57{\pm}2.67$ vs. $3.64{\pm}2.30$ ; p=0.013)는 남학생보다 유의하게 높았다. 그러나 성별, 과거 정신과 치료력을 통제한 후, 매우 높은 수준의 우울과 불안 상태에서 남학생이 수면 곤란을 경험할 위험도가 여학생에 비해 현저히 높았다(CDI aOR, 14.66 ; 95% CI, 4.17-51.53, BAI aOR, 32.99 ; 95% CI, 4.26-255.39). 결 론 이 연구 결과는 여학생에 비해 남학생에서 우울과 불안의 정도가 심각할 때 수면 곤란을 경험할 위험이 더욱 높다는 것을 시사한다. Objectives : The aim of the study was to investigate the prevalence by gender and to evaluate associations of depression, anxiety and sleep disturbances in a large sample of adolescents from the general population. Methods : 1422 subjects, aged 14 years students were recruited in the seven middle-school of the local community. The self-report questionnaire(Children's Depression Inventory : CDI, Beck Anxiety Inventory : BAI and Pittsburgh Sleep Quality Index : PSQI) was used for screening depression, anxiety and sleep disturbances in adolescent. CDI, BAI, and PSQI score was categorized into the following quartiles : $\leq$21, 22-25, 26-28, and $\geq$29 ; $\leq$21, 22-26, 27-31, and $\geq$32 ; $\geq$5, <5. The cut-off score is that CDI is 22, BAI is 22 and PSQI is 5. The result was analyzed using the independent t-test, the chi-square test and logistic regression analyses. Results : The mean CDI score($12.52{\pm}8.32$ vs. $10.39{\pm}7.52$ ; p=0.003), BAI($7.77{\pm}7.93$ vs. $9.84{\pm}9.04$ ; p<0.001) and PSQI($4.57{\pm}2.67$ vs. $3.64{\pm}2.30$ ; p=0.013) of girls were significantly higher than for boys. But, boys in the fourth quartile of CDI(CDI$\geq$29) and BAI(BAI$\geq$32) were at significantly elevated risk for sleep disturbances more than for girls after adjustment for sex, history of psychiatric treatment(CDI odd ratio, 14.66 ; 95% CI, 4.17-51.53, BAI odd ratio, 32.99 ; 95% CI, 4.26-255.39). Conclusion : The results suggest that high CDI, BAI score appears to increase the risk for developing sleep disturbances in boys more than girls.

Korean-version of Mini-Mental State Examination 검사에서 기억회상 0점 노인을 대상으로 한 1년 뒤 치매 이행률에 대한 예비 연구

홍윤정,양동원,윤보라,심용수,조아현,한일우,문명성 대한노인병학회 2014 Annals of geriatric medicine and research Vol.18 No.1

Background: The early stage of Alzheimer disease might show early memory impairment with normal general cognitive function. Our study aimed to investigate elderly with normal Korean version of mini-mental state examination (KMMSE) score and recall score of 0 for 1 year. We predicted that the patients would show different characteristics and would progress more rapidly compared with normal controls. Methods: This study was based on the data from complete enumeration survey of Mapo-gu Regional Center for Dementia in 2009. We divided all subjects into three groups: subjects with normal K-MMSE scores and recall score of 0 were group 1-1 (n=152), subjects with abnormal K-MMSE scores were group 1-2 (n=64) and subjects with normalK-MMSE scores and recall score of 1 to 3 were group 1-3 (n=941). We compared basic demographics and social characteristics among the three groups. After 1 year (2010), the subjects in group 1-1 (90 out of 152) underwent follow-up examinations for dementia diagnosis. They were also divided into three groups (2-1, 2-2, 2-3) according to K-MMSE and recall scores. Results: Group 1-1 showed different baseline characteristics compared with normal controls. After 1 year, 25.5% (23 out of 90) of the group 2-1 were diagnosed as mild cognitive impairment (n=16) or dementia (n=7). Conclusion: Our study suggested that subjects with normal K-MMSE scores but recall score of 0 are not entirely “normal”. Further detailed evaluation might be needed if memory impairment is suspicious although the K-MMSE scores are within normal range. 연구배경: 초기 알츠하이머병에서는 전반적인 인지기능이정상임에도 불구하고 초기부터 기억력 저하가 나타난다. 우리연구에서는 K-MMSE 점수가 정상 범위 내에 있었으나, 기억회상 점수가 0점이었던 피험자들을 대상으로 하는 1년 추적검사를 계획하였다. 우리는 피험자들이 정상 대조군과는 인구사회학적으로 다른 군이며, 치매로의 진행도 빠를 것으로 예상하였다. 방법: 본 연구는 마포구 치매지원센터에서 2009년에 진행된 전수조사 결과를 바탕으로 하였다. 전체 피험자들을 세 그룹으로 분류하였는데, 정상 범위 내의 K-MMSE 점수를 보였으나, 기억회상 점수가 0점이었던 피험자들을 그룹 1-1로(n= 152), K-MMSE 점수가 비정상 소견을 보였던 피험자들을 그룹 1-2로(n=64), 그리고 정상 K-MMSE 점수와 1점 이상의기억회상 점수를 보였던 피험자들을 그룹 1-3으로(n=941) 정하였다. 전체 피험자들의 인구통계학적 정보를 그룹 간 비교하였고, 그룹 1-1에 속했던 피험자들을 대상으로 1년 뒤재검사를 시행하여 이들의 치매발병률을 분석하였다. 결과: 그룹 1-1의 피험자들은 2009년 전수조사에서 정상대조군인 그룹 1-3의 피험자들과는 다른 인구 통계학적 특성을 보였다. 1년 뒤, 그룹 1-1의 피험자 중 약 28.4%가 경도인지 장애 또는 치매를 진단받았다. 결론: 이번 연구 결과를 바탕으로 치매선별검사로 많이 시행되는 K-MMSE 점수가 정상 범위 내에 있다고 하더라도 기억회상 점수가 0점에 해당한다면 이는 완전한 ‘정상’이 아니라고 의심해 볼 수 있겠다. 이를 확인하기 위해 더 큰 규모의전향적인 연구가 필요할 것으로 생각된다.

Infantile Cortical Hyperostosis 1례

엄영관,박은희,오수미,오경영,고영숙,윤경애,문명성,변화진 최신의학사 1993 最新醫學 Vol.36 No.12

경도인지장애 환자의 집단 작업치료 및 음악치료의 효과

임은예,양동원,심용수,윤보라,홍윤정,문명성 대한노인병학회 2015 Annals of geriatric medicine and research Vol.19 No.2

Background: Patients with mild cognitive impairment (MCI) are at an increased risk for developing dementia, especially Alzheimer disease; and pharmacological therapy for MCI is limited. As a result, nonpharmacological mediums have been considered to complement standard drug therapy. In this study, we evaluated the effects of nonpharmacological therapies, occupational therapy and music therapy, on cognitive functions and depressive mood in MCI patients. Methods: We enrolled patients with MCI from the Mapo Dementia Center and divided them into two groups, group A (n=14) who participated in a cognitive program for 12 months and group B (n=15) who did not participate in a cognitive program. We compared the baseline and followed-up scores of the Korean-version of Mini-Mental State Examination (K-MMSE), the Seoul Neuropsychological Screening Battery (SNSB), and the short version of geriatric depression scale (sGDS) between the two groups. Results: Group A showed improvements in total and language scores in the K-MMSE and digit span backward scores in the SNSB and sGDS. In contrast, group B showed a decline in the Seoul Verbal Learning Test recognition score in the SNSB. Additionally, there were significant intergroup differences in the total and language scores in K-MMSE, the digit span backward score, and the Rey Complex Figure Test-delayed recall scores and depression scores. Conclusion: Occupational therapy and music therapy may help to improve cognitive functions and depressive mood in patients with MCI.