소회향이 허혈성 뇌혈관 질환에 미치는 실험적 연구

강성용 ( Sung Yung Kang ),김남순 ( Nam Soon Kim ),정현우 ( Hyun Woo Jeong ) 대한한방신경정신과학회 2007 동의신경정신과학회지 Vol.18 No.1

Objective : This experimental Study was designed to investigate the effects of FOENICULI FRUCTUS(FF) on the change of inhibition lactate dehydrogenase(LDH) activity in neuronal cells and cytokines production in serum of cerebral ischemic rats.Method : FOENICULI FRUCTUS(FF)freeze dry powder and FF on the LDH activity in neuronal cells. Changes of FF on the physiological parameters(PaO2, PaCO2, MABP and HR) in crerbral ischemic rats. Effects of FF on the IL-1beta production, TNF-α production, TGF-β production, and IL-10 in serum of cerebral ischemic rats.MCAO : cytokines production of serum by drawing from femoral arterial blood after MCAO 1 hr. Reperfusion : cytokines production of serum by drawing from femoral arterial blood after reperfusion 1 hr.Results and Conclusion :1. FF did not inhibit lactate dehydrogenase(LDH) activity in neuronal cells.2. In serum by drawing from femoral arterial blood after middle cerebral arterial occlusion(MCAO) 1 hr and reperfusion 1 hr, sample group was significantly decreased IL-1β production compared with control group.3. In serum by drawing from femoral arterial blood after MCAO 1 hr and reperfusion 1 hr, sample group was significantly decreased TNF-α production compared with control group.4. In serum by drawing from femoral arterial blood after MCAO 1 hr and reperfusion 1 hr, sample group was significantly increased TGF-β production compared with control group.5. In serum by drawing from femoral arterial blood after reperfusion 1 hr, sample group was significantly increased IL-10 production compared with control group. This results were suggested that FF had inhibitive effect on the brain damage by inhibited LDH activity, IL-1β and TNF-α production, but accelerated TGF-β production and IL-10 production.

Overproduction of Human Interleukin-2 in E. coli

강성만,김성완,하현정,나도선,박순희,김지영,한문희,Kang, Seong-Man,Kim, Sung-Wan,Ha, Hyun-Jung,Na, Doe-Sun,Park, Soon-Hee,Kim, Ji-Young,Han, Moon-Hi 생화학분자생물학회 1988 한국생화학회지 Vol.21 No.1

본 논문에 앞서 사람 인터루킨-2(IL-2)의 cDNA 클론을 분리하였음을 보고하였다 (강성만 등, 1987). 본 보고에서는 이 cDNA클론을 이용하여 E. coli 에서 인터루킨-2를 발현시킨 결과를 보고한다. E. coli 에서 인터루킨-2를 생산하기 위하여 플라스미드 pNK2를 만들었다. 이 플라스미드에는 인터루킨-2를 코딩하는 유전자가 람다파아지의 $P_L$ 프로모터의 조절을 받도록 클로닝 되어 있다. 온도감수성 억제유전자(${\lambda}$ cIts857)를 만드는 E. coli lysogen 균주에 플라스미드 pNK2를 transformation 시켰다. 인터루킨-2의 발현을 유도하기 위하여 배양온도를 $42^{\circ}C$로 올렸을 때 세포내에 inclusion body가 형성되었음이 관찰되었다. 재조합된 유전자를 지난 E. coli에서 합성된 단백질을 SDS-폴리아크릴아마이드 젤에서 분리하였을 때 인터루킨-2의 분자량에 해당하는 15 Kd의 단백질이 관찰되었다. 이 단백질이 인터루킨-2의 활성을 지니고 있음을 인터루킨 의존성 cell line인 MTL 세포의 성장을 촉진시키는 것으로서 확인하였다. 즉 이 15 Kd 분자량의 단백질이 E. coli에서 생산된 재조합 인터루킨-2임을 보였다. 이 인터루킨-2 단백질은 E. coli 에서 생산된 총 단백질의 약 20% 에 해당하였다. A cDNA clone for human interleukin-2(IL-2) has been isolated (Kang et al., 1987). Plasmid pNK2 was constructed in order to obtain the expression of IL-2 in E. coli. In plasmid pNK2, the coding sequence was placed under the control of phage ${\lambda}$ promoter $P_L$. An E. coli ${\lambda}$ lysogenic strain carrying a temperature sensitive repressor (${\lambda}$ cIts857) was transformed with pNK2 and the expression of IL-2 cDNA was induced by raising the temperature to $42^{\circ}C$. The inclusion bodies were observed in recombinant E. coli cells after induction. When the proteins of the recombinant cells were separated on a SDS-polyacrylamide gel, a 15Kd protein band corresponding to the M.W. of IL-2 was observed. The 15Kd protein showed IL-2 activity as determined by the growth romoting effect on a IL-2 dependent cell line MTL. Therefore, it was demonstrated that the 15Kd protein was recombinant IL-2 produced in E. coli. The recombinant IL-2 represented about 20% of the total E. coli protein.

궤도형식별 사용레일의 피로수명 평가

강성원(Sung Won Kang),임형준(Hyung-Jun Lim),박용걸(Yong-Gul Park) 한국철도학회 2017 한국철도학회논문집 Vol.20 No.5

RC 구조물 FREP 휨 보강을 위한 해석적 연구

강성후(Sung-Hoo Kang),박선준(Sun-Joon Park),김민성(Min-Sung Kim) 한국콘크리트학회 2004 콘크리트학회논문집 Vol.16 No.4

Experimental Study on the Mix Design Method using the Fracture Energy and the other Parameters in Concrete.

Kang, Sung-Hoo(강성후) 한국콘크리트학회 1992 콘크리트학회논문집 Vol.4 No.4

동적하중을 받는 콘크리트 보의 파괴거동

강성후(Kang, Sung Hoo),김우(Kim, Woo),박선준(Park, Sun Joon) 한국콘크리트학회 1996 콘크리트학회논문집 Vol.8 No.1

어휘와 독해에서 키워드 전략의 효과

강성관 ( Kang Sung Kwan ) 아시아문화학술원 2017 인문사회 21 Vol.8 No.4

본 연구는 어휘와 독해 학습에서 키워드 학습 전략의 효과를 알아보기 위하여 진행되었다. 어휘와 독해 학습에서 키워드 학습 전략의 효율성을 증명하기 위하여 실험집단에게는 키워드 학습전략을, 통제집단에게는 전통적 학습전략을 응용하였다. 두 집단의 학습효과와 성취도 파악을 위해 사후 테스트와 사후 지연 테스트를 실시하였다. 사후 테스트 결과 어휘와 독해학습에서 실험집단의 성취도가 통제집단보다 높게 나타났고 사후 지연 테스트에서도 학습자의 성취도가 매우 높게 나타났다. 참여자들의 수업 만족도 측정에서도 키워드 학습 전략을 응용한 실험집단이 더 높게 나타났다. 이 연구의 결과를 토대로 키워드 학습 전략의 효율성을 확인함과 동시에 한국인 영어 학습자를 위한 키워드 학습전략의 다양한 접근법이 필요하다고 본다. The study investigates the effectiveness of the keyword approach. The keyword learning strategy was applied to the experimental group and the traditional learning approach for the control group. After the applications of the two learning strategies, the two groups were given immediate and delayed post-test to identify and compare their achievement. The results indicated that the experimental group achieved higher at the immediate post-test. The experimental group also achieved noticeably higher after two weeks of delayed test. The survey showed the experimental group with the keyword approach expressed more positive opinions. This study has verified that the keyword approach can an efficient learning strategy. The study also suggests the adaptation of the keyword learning approach can be explored further for its benefits for Korean English learners.

농촌기본소득의 구약성서적 전거(典據)에 관한 연구

강성열(Sung Yul Kang) 전남대학교 종교문화연구소 2023 종교문화학보 Vol.20 No.2

근래 들어 사회적 불평등과 양극화 현상을 극복하기 위한 목적으로 기본소득에 관한 논의가 활발하게 진행되고 있다. 그러나 모든 국민에게 지급하게 될 기본소득은 가장 먼저 온갖 악조건 속에서 힘겹게 식량 주권을 지켜내고 있는 이 땅의 농민들에게 지급되어야 한다. 농촌기본소득이 바로 그것이다. 도시화와 산업화의 과정에서 도농소득의 격차가 갈수록 심해지면서, 현저한 이농 현상으로 인하여 농촌 지역은 초고령화 사회로 진입한 지 오래다. 더욱이 예측 불가능한 기후변화 때문에 이제는 곡물 생산 감소와 곡물 수출 금지 내지는 식량 무기화로 인한 먹거리 위기와 식량 대란을 걱정하지 않을 수 없게 되었다. 일정액의 농촌기본소득을 모든 농촌 사람들 개개인에게 정기적으로 개별적으로 지급함으로써 미래의 식량 안보와 식량 주권을 지켜야 한다는 주장이 그래서 나오는 것이다. 안타깝게도 우리 시대의 농민들은 하나님의 형상을 따라 창조된 존귀한 자들이면서도, 급속한 소득 감소와 초고령화 추세로 인하여 고통을 당하고 있다. 그러기에 구약성서의 다양한 약자 보호 규정들이 보여주는 것처럼, 정부는 경제적 자립과 안정된 소득을 조금이라도 배려하는 차원에서 그들 모두에게 동일한 농촌기본소득을 지급함으로써, 사회적 약자들인 그들이 아무런 걱정 없이 농업과 농촌을 살려내는 일에 전념할 수 있게 해야 한다. 희년 제도가 가르치는 삶의 평등성, 그리고 광야의 식탁과 땅의 공평한 분배가 가르치는 균등하고도 차별없는 삶의 보장 역시 농촌기본소득의 정당성을 뒷받침하는 것이 아닐 수 없다. 농업과 농촌이 국민의 생명 먹거리를 생산하고 보급할 뿐만 아니라, 자연 생태계를 지켜내는 역할을 수행하는 등의 공익가치를 가지고 있음을 주목한다면, 미래의 식량 자원을 지키기 위해서라도 구약성서의 가르침에 기초하여 신속하게 농촌기본소득이 모든 농촌 사람들에게 지급되게 함으로써, 농촌 사람들이 농촌을 떠나지 않고 안정된 생계 기반 아래에서 식량 생산의 중대한 임무를 수행하게 도와야 할 것이요, 장기적으로는 생계 안정을 원하는 사람들의 귀농을 도움으로써 농업과 농촌이 식량 주권을 지켜낼 수 있는 사람들로 가득하게 만들어야 할 것이다. In recent years, discussions on basic income have been actively conducted for the purpose of overcoming social inequality and polarization. However, the basic income to be paid to all citizens should be paid first to farmers in the land who are struggling to protect their food sovereignty under all kinds of unfavorable conditions. Rural basic income is what it is. As the gap in urban and rural income intensifies in the process of urbanization and industrialization, rural areas have long entered a super-aged society due to the remarkable migration phenomenon. Moreover, unpredictable climate change has forced us to worry about the food crisis and food chaos caused by declining grain production and banning grain exports or weaponizing food. This is why it is argued that a certain amount of basic rural income should be paid to all rural people on a regular basis to protect future food security and food sovereignty. Unfortunately, the peasants of our time are the noble created in the image of God, but they are suffering from rapid income decline and the trend of super-aging. So, as the Old Testament's various protection regulations show, the government should give them all the same basic rural income in terms of economic independence and stable income, so that they, the socially disadvantaged, can concentrate on saving agriculture and rural areas without any worries. The equality of life taught by the jubilee system and the guarantee of an equal and non-discriminatory life taught by the equitable distribution of tables and lands in the wilderness also support the legitimacy of basic rural income. Not only does agriculture produce and distribute food for the people, but it also has public interest values such as protecting the natural ecosystem, so that basic rural income can be quickly paid to all rural people, not leaving the country, to help them secure their long-term livelihood. Note that agriculture and rural areas not only produce and distribute the people's life food, but also have public interest values such as playing a role in protecting the natural ecosystem. In order to protect future food resources, rural basic income should be quickly paid to all rural people based on the Old Testament's teachings to help rural people carry out important tasks of food production under a stable living base, and in the long run, agriculture and rural areas should be filled with people who can protect food sovereignty by helping those who want to stabilize their livelihoods return to farming.

한국 형사사법제도에서의 견제와 균형 원칙에 대한 비교법적 연구

강성용(Kang, Sung Yong) 한국형사정책학회 2018 刑事政策 Vol.30 No.2

The Prosecutor s Office, an organization carrying out an imperative role in the criminal justice system, is a legacy of the principle of checks and balances attainable through a functional separation of powers. The principle of checks and balances achievable through a functional separation of powers has been recognized as a natural law based on an intrinsic human nature applicable to all times and places by all the states, and even long before the emergence of the concept of state as a sovereignty. However, ironically in Korea, the principle which brought forth the Prosecutor s Office in the criminal justice system has been collapsed by the Prosecutor s Office itself. Even when no checks and balances on the natural function of the Prosecutor s Office―prosecution authority as its name signifies―exists in Korea unlike the other states compared such as U.S, U.K, France and Germany in this research, Korea is the only state where the Prosecutor s Office dominates an additional crucial function―investigation authority―in the criminal justice system. A discretionary authority to request a warrant as an indispensable investigative measure has been monopolized by the Prosecutor s Office. Furthermore, the Prosecutor s Office is prescribed with a robust authority to direct investigations of the National Police Agency backed up by a legal obligation of police officers to obey the directions of prosecutors and an authority to request a removal or disciplinary action against disobeying police officers. The Prosecutor s Office are provided with personnel and material resources as well as a legal authority to actually investigate crimes by itself. The global standard is checks and balances attainable through functional separation of investigation and prosecution. However, despite of the fact that Korea requires a strict functional separation of investigation and prosecution to incorporate the principle of checks and balances into its criminal justice system more than any other states compared as checks and balances on the prosecution authority as a natural authority of the Prosecutor s Office is absent, the Prosecutor s Office in Korea dominates even investigations in addition to prosecutions. We have witnessed serious negative outcomes brought by the collapse of checks and balances and functional separation of powers allowing excessive or insufficient exercises of authorities by the Prosecutor s Office on its own discretion. Sadly, people―the ultimate source of any and all governmental power―have lost their belief in the Prosecutor s Office which was supposed to establish and promote the fairness and rule of law. Prosecutors are not angels but men. All men having power ought to be mistrusted. Now it is time for the Prosecutor s Office in Korea to return to its original position in accordance with the principle of checks and balances and a functional separation of powers which gave birth to the Prosecutor s Office in the criminal justice system. For this purpose, by analyzing impartial and proper methodological principles of comparative legal studies on the criminal justice system, this paper aims to provide the answers to the following questions: what and why important is the principle of checks and balances and a functional separation of powers as a natural law; in what manner and degree does the criminal justice system of other states comply with the principle; and what is the future direction and current problem of the criminal justice system of Korea from the perspective of such principle.

스펙트럼 확산 시스템에서 동기에 관한 연구

강성봉(Sung Bong KANG),김원후(Won Hoo KIM) 한국통신학회 1984 한국통신학회 학술대회논문집 Vol.1984 No.11