Coronary Artery Bypass Grafting vs. Drug-Eluting Stent Implantation for Multivessel Disease in Patients with Chronic Kidney Disease

강세훈,이철환,윤성철,이필형,안정민,박덕우,강수진,이승환,김영학,박성욱,박승정 대한심장학회 2017 Korean Circulation Journal Vol.47 No.3

Background and Objectives: There is currently a limited amount of data that demonstrate the optimal revascularization strategy for chronic kidney disease (CKD) patients with multivessel coronary artery disease (CAD). We compared the long-term outcomes of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus coronary artery bypass graft surgery (CABG) for multivessel CAD in patients with CKD. Subjects and Methods: We analyzed 2108 CKD patients (estimated glomerular filtration rate <60 mL/min/1.73 m2) with multivessel CAD that were treated with PCI with DES (n=1165) or CABG (n=943). The primary outcome was a composite of all causes of mortality, myocardial infarction, or stroke. The mean age was 66.9±9.1 years. Results: Median follow-up duration was 41.4 (interquartile range 12.1-75.5) months. The primary outcome occurred in 307 (26.4%) patients in the PCI group compared with 304 (32.2%) patients in the CABG group (adjusted hazard ratio [HR], 0.941; 95% confidence interval [CI], 0.79–1.12; p=0.493). The two groups exhibited similar rates of all-cause mortality (adjusted HR, 0.91; 95% CI, 0.77–1.09; p=0.295), myocardial infarction (adjusted HR, 1.86; 95% CI, 0.85–4.07; p=0.120) and stroke (3.2% vs. 4.8%; HR, 0.93; 95% CI, 0.57–1.61; p=0.758). However, PCI was associated with significantly increased rates of repeat revascularization (adjusted HR, 4.72; 95% CI, 3.20–6.96; p<0.001). Conclusion: Among patients with CKD and multivessel CAD, PCI with DES when compared with CABG resulted in similar rates of composite outcome of mortality from any cause, MI, or stroke; however, a higher risk of repeat revascularization was observed.

어업에서의 보합제도의 경제학적 의미에 관한 연구

유동운,강세훈 釜山水産大學校 1992 論文集 Vol.48 No.-

The argument of share-cropping and cost-sharing in fishing industry has received considerable attention in the literature of Japanese and Korean fishery economists. In addition the pros and cons on the share-cropping have been unanswered to require a substantiual analysis on explanation of the existence of the system. This paper intends to answer two questions ; Firstly why the share-cropping and cost-sharing system in fishing industry has been instituted for so long unchanged?, Secondly Does the system assure the Pareto efficient solution on the distribution of harvest between fishing vessel owner and fishermen? To answer these questions this paper introduced the uncertainty theory in economics into the fishing activity. As a consequence optimizing economic agents of owner and fishermen to avoid risk in variations in fish catch and price naturally are in favor of share-cropping against either of fixed wage from or rent payment to the vessel owner. Fishermen in danger of delving themselves into moral hazard in the absence of the verification of their activity at sea refuse to be idle in fishing. Moreover fishermen endowed with entrepreneurship in fishing voluntarily which prevails probably in the fixed wage system. This conclusion is supported by the existence of share tenancy in agriculture. However widespread presence of asymmetric information on the fishing condition at sea between the vessel owner and fishermen forces for both to enter into agreement of sharing of costs accrued in the navigation for the sake of their benefits.

資源經濟學과 厚生經濟學과의 關係 考察

李承來,姜世勳 釜山水産大學校 1985 論文集 Vol.35 No.-

Natural resource and environmental economics applies economic theory and methods of quantative analysis to public-policy problems in the provision, allocation, distribution, and conservation of natural resources and environmental amenities. However, because of the unique nature of resources themselves and the issues associated with resource economics, it will be necessary to expand our economic theory into serveral additional demension. As such, it is a subfield of the broader field of social microeconomics, in which microeconomics and welfare economics are applied to the solution of problems of public policy concerns. The focus is on social costs and benefits of proposed actions and public-policy solution to problems that have impacts across individuals, firms, industrial sectors, economic classes, and often, regional and national boundaries. In social microeconomics, the analysis of individual producer and consumer decisions is seldom the ultimate goal. Rather, it is an intermediate step in the analysis of public-policy issues. Thus, its approach takes positive and normative economic analysis. The major concern of resource economics are resource allocation in the present and in the future, and the distributional outcomes of resource allocation decision. Thus resource economics raise questions about the effectiveness of existing market and institutional structures in allocating resources, in adjudicating among the claims of individuals in the present generation, and adjudicating between the claims of present and future generations. Resource economics focuses on policy questions with respect to natural resources. It seek to analyze problems in the allocation of natural resources, to identity the causes of those problems, and to identify and examine alternative programs, policies, and projects being proposed as solutions. Above all problems are included in welfare economic theory. The knowledge of applied welfare economic theory is essential to the provision of useful and appropriate policy information. Especially, it is providing quantative information on the welfare effects of alternative policy measures. This study provides a through review of economic welfare theory and illustrates how this theory can be used to obtain policy information in the area of the economics of natural resources.

A Semantic Service Discovery Network for Large-Scale Ubiquitous Computing Environments

강세훈,이영희,이동만,Daewong Kim,현순주,벤리 한국전자통신연구원 2007 ETRI Journal Vol.29 No.5

This paper presents an efficient semantic service discovery scheme called UbiSearch for a large-scale ubiquitous computing environment. A semantic service discovery network in the semantic vector space is proposed where services that are semantically close to each other are mapped to nearby positions so that the similar services are registered in a cluster of resolvers. Using this mapping technique, the search space for a query is efficiently confined within a minimized cluster region while maintaining high accuracy in comparison to the centralized scheme. The proposed semantic service discovery network provides a number of novel features to evenly distribute service indexes to the resolvers and reduce the number of resolvers to visit. Our simulation study shows that UbiSearch provides good semantic searchability as compared to the centralized indexing system. At the same time, it supports scalable semantic queries with low communication overhead, balanced load distribution among resolvers for service registration and query processing, and personalized semantic matching.

The development of a fully automated homemade system for [11C]acetate synthesis using an open source PLC

강세훈,홍성탁,박광서,김석기 대한방사성의약품학회 2016 Journal of radiopharmaceuticals and molecular prob Vol.2 No.2

Solid phase extraction (SPE) purification method is the efficient and well-known tool for automated [11C]acetate synthesis. A fully automated homemade module adopting the SPE method and ‘pinch’ valves was developed very economically with a universal interface board, a relay card and an open source programmable logic controller. The radiochemical yield of the optimized [11C]acetate synthesis by this system was 58.8 ± 2.1% (n=10, decay-corrected) from 15.5 ± 0.19 GBq of [11C]CO2 as starting activity, and total synthetic time was 15 minutes. HPLC analysis showed its high radiochemical purity as 97.4 ± 1.1% without possible by-products. J Radiopharm Mol Probes 2(2):103-107, 2016

海洋環境資源의 效率的 利用을 위한 所有權確立에 關한 考察

姜世勳 釜山水産大學校 1984 論文集 Vol.32 No.-

Traditionally, mankind has made use of the oceans in several forms. Because ocean pollution has significant effects on many ocean uses, it seems reasonable to classify ocean uses into two categories; waste disposal and all other uses which are usually called amenity uses. These two uses are competitive. Historically, the oceans have been ruled by the principle of freedom of the high seas. So, the oceans have been common property resources, which tend to be over-used and polluted by everybody. Therefore, competitive uses impose external diseconomies on each other. Since World War II, population growth and improvement in the standard of living have brought about the increase of demands for the marine resources, as a result the prices of them have increased rapidly. At the same time, advance in technologies has fallen the cost of coastal nations for enclosure of broader ocean area. Old common property structure which had ruled the ocean used has poorly attuned to new market opportunities. Ownership rights structure tends to change when the value of better defined property rights exceeds the cost of bringing them about. After 1945, there was establishment of property rights to the oceans by coastal nations. Many of these actions have been motivated more by distributional self-interest than by attempts to internalize the external effects and secure efficient use of marine resources. In 1967, the opposition to further enclosure by the coastal nations began to mount. Many counties favored the establishment of an equitable international jurisdiction over the marine resources. In the case of marine environmental resources, economic analyses of the consequences of the enclosure movement versus international jurisdiction process by the UNCLOS(U.N. Conference on the Law of the Sea) strongly suggest that the enclosure movement will secure efficient use of them. I think so. But I think the most efficient property structure to the marine environmental resource is enclosure by the coastal nations together with international payment network in order to be compensated by offender. I think therefore that for the efficient control of marine pollution there should be international cooperation to create payment network. To do this each nation should encourage herself both from adopting extreme positions for negotiating purposes and over-estimating the cost of environmental damage and pollution control costs. That will reduce transactions cost and ease international cooperation. Then, efficient use of marine environmental resource is attained, that is to say, ocean pollution will be reduced to the optimal level.

제43차 대한핵의학회 추계학술대회 : 포스터 ; [18F]16α -Fluoroestradiol(FES)의 자동화 합성

강세훈,오승준,길희섭,지대윤,류진숙,문대혁 대한핵의학회 2004 핵의학 분자영상 Vol.38 No.5

복음화2000-내가 하고 싶은 이야기

강세훈 우리신학연구소 1999 갈라진 시대의 기쁜소식 Vol.- No.414

Impact of Follow-Up Ischemia on Myocardial Perfusion Single-Photon Emission Computed Tomography in Patients with Coronary Artery Disease

강세훈,김영학,최효인,이은영,안정민,한승봉,이필형,노재형,윤성한,박덕우,강수진,이승환,이철환,문대혁,박성욱,박승정 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.5

Purpose: Few studies have reported on predicting prognosis using myocardial perfusion single-photon emission computed tomography(SPECT) during coronary artery disease (CAD) treatment. Therefore, we aimed to assess the clinical implications of myocardial perfusion SPECT during follow-up for CAD treatment. Materials and Methods: We enrolled 1153 patients who had abnormal results at index SPECT and underwent follow-up SPECT at intervals ≥6 months. Major adverse cardiac events (MACE) were compared in overall and 346 patient pairs after propensity-score (PS) matching. Results: Abnormal SPECT was associated with a significantly higher risk of MACE in comparison with normal SPECT over the medianof 6.3 years (32.3% vs. 19.8%; unadjusted p<0.001). After PS matching, abnormal SPECT posed a higher risk of MACE [32.1% vs. 19.1%; adjusted hazard ratio (HR)=1.73; 95% confidence interval (CI)=1.27–2.34; p<0.001] than normal SPECT. After PS matching,the risk of MACE was still higher in patients with abnormal follow-up SPECT in the revascularization group (30.2% vs. 17.9%; adjusted HR=1.73; 95% CI=1.15–2.59; p=0.008). Low ejection fraction [odds ratio (OR)=5.33; 95% CI=3.39–8.37; p<0.001] and medical treatment (OR=2.68; 95% CI=1.93–3.72; p<0.001) were independent clinical predictors of having an abnormal result on follow-up SPECT. Conclusion: Abnormal follow-up SPECT appears to be associated with a high risk of MACE during CAD treatment. Follow-up SPECT may play a potential role in identifying patients at high cardiovascular risk.

經常計定 模型의 比較考察

金銀埰,姜世勳 釜山水産大學校 1987 論文集 Vol.38 No.-

In this paper, we examine the current account model and the related topics. current account, in general, can be written equivalently as the sum of the trade account and the service account, as income minus absorption, or as saving minus investment. In classical two articles, Harberger(1950) and Laursen and Metzler(1950) postulated that saving out of any given level of income decreases with a deterioration of the terms of trade. Their argument was discribed as following: A terms of trade deterioration decreases real income, and the decrease in real income reduces saving out of any given income, both measured in terms of exportables, Thus, if investment is constant and there in no government deficit, the change in saving is, as defined, equal to the change in the current-account surplus, and hence the Harberger-Laursen-Metzler effects implies that the current account will deteriorate in response to a terms of trade deterioration. The Harberger-Laursen-Metzler effect played an important role in the discussion of the relative merits of elasticity and absorption approaches to the effect of devaluation on the trade balance and balance of payments. Section 2, we present the elasticities and absorption approach, respectively and debate over them. Section 3, we introduce the Sack's model and apply an intertemporal framework in discussing the current account over time. Section 4. we show the relationship between current account and the terms of trade blance.