ACD혈액희석관류의 산염기평형 : Helix 및 Rygg-Kyvsgaard 산화기 사용례

김종환,최지원,김정석,손광현,서경필,이영균 서울의대 1969 서울의대잡지 Vol.10 No.4

일부 자동차 공장 근로자들의 職業的 特性과 社會 心理的 Stress의 相關性 硏究

김성삼,홍지우,한현정,최희석,권소희,정해경,김삼태,송용선,이기남 한국전통의학연구소 2004 한국전통의학지 Vol.14 No.1

〈Objective〉 This study were carried out to study to assess the relationship between job characteristics, general characteristics, health behaviors, and psychosocial distress and suggested the preventive oriental medicine approaches in occupational health area. 〈Methods〉 We measured job characteristics(job demand, job control, jop insecurity) by The Karasek's Job Content Questionnaire, health behaviors(smoking, drinking, exercise, coffee), general characteristics at work by a self-administered questionnaire. Psycho social distress was measured by PWI(Psychosocial Well-being Index), a 18-item self- administered instrument. 370 data for research were collected through the process of oriental health examination with questionnaire in workplace. Statistical analysis was done by t test, oneway ANOVA, and hierarchical multiple regression analysis with SPSSWIN (version 10.0) 〈Results〉 Among the 152 respondents, the prevalence of high job strain was 27%(41 persons). The Odds ratio of high job strain was 3.11(95 2.12~4.11), and those of passive group and active group were 2.01(95 0.83~2.76) and 1.80(95 0.83~2.76), respectively. Our results supported the association between psychosocial distress and job strain. 〈Conclusion〉 The odds ratio of high strain isolated group(high strain group+low social support) was 3.59(95 2.05 5.13), but the odds ratio of high strain collective group was 1.32(95 0.23 2.41). Social support at work was modifing factor of the association between psycho social distress and job strain. Therefore we reviewed the evidence that economic depression was associated with psycho social distress in this study, and that the strength of the social support was important in maintain health.

간과된 건성 추지의 수술적 치료

김융성,서중배,이석재,홍장수 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.2

연구목적 . 손상 후 3주 이상 경과된 건성 추지에 대하여 tuft를 만들어 주고 신전상태에서 K-강선으로 고정하는 수술적 치료 방법의 유용성을 분석하고자 하였다. 대상 및 방범: 1997년 8월부터 2001년 3월까지 본 교실에서 건성 추지로 치료받은 예 중 손상 후부터 3주 이상 경과된 환자 11예를 대상으로 하였다. 평균 추시 기간은 7개월(3개월-9개월)이었으며, 평균 연령은 19세(2년 3개월-48세)였다. 11예 중 4예는 15세 미만의 소아였다. 수상 후 수술까지 경과된 기간은 평균 12개월(3주-7년)이었다. 우측 수부가 7예였고, 좌측은 4예였다 수지 별로는 인지가 3예, 중지가 4예, 약지가 2예, 소지가 2예였다. 모든 예에서 신전건의 절단, K-강선에 의한 원위지 관절의 고정, tuft의 형성, Roll-stitch 등의 동일한 방법을 사용하였으며, 최종 추시일에 Crawford 평가방법을 사용하여 환자를 평가하였다. 결과: Crawford의 방법을 이용한 평가 결과, 11예 중 7예(64%)가 우수(Excellent)의 결과를 보였고, 3예(27%)는 우량(Good), 1예(9%)는 양호(Fair)로 판명되었다. 즉 11예 중 1예를 제외하고는 모두, 즉 91%에서 만족스런 결과를 얻었다 우량 또는 양호의 결과를 보였던 4예의 경우 수상 후 경과된 기간이 각각 4개월, 9개월, 3년, 7년으로 수상 후 경과된 기간이 길수록 결과가 나빴다. 15세 미만의 소아 4예는 모두 우수한(Excellent) 결과를 보였고, 반면에 양호로 판정된 환자는 연령이 48세로 대상 환자 중 가장 고령이었다. 손상된 수지가 좌측이거나 우측인지 여부와 몇 번째 수지인지 여부는 결과와 무관한 것으로 보인다. 성별과도 관련성을 알 수 없었다. 결론: 손상 후 상당기간이 경과한 후에도 비교적 간단한 수술 방법에 의한 치료가 가능하였으며, 결과도 만족스러웠으나, 지나치게 오래된(손상 후 수 개월 이상이 경과한) 건성 추지의 경우, 그리고 나이가 많은 경우 예후가 좋지 않다는 사실을 알게 되었다. Purpose : The authors have attempted to analyze the effectiveness of making tuft and fixing the distal interphalangeal joint in extension with a K-wire in patients whose injured finger were left over 3 weeks without treatment for the tendinous mallet finger. Materials and Methods : Eleven fingers of eleven patients were analyzed who were treated operatively from August 1997 to March 2001. The average follow-up period was 7 months(3-9 months). The average age of the patients was 19 years(2 years 3 months-48 years) Four out of the 11 cases were children under age of 15. The average duration between injury and operation was 12 months(3 weeks-7 years) . All cases were treated by only one surgeon(Seo, JB) and with same procedure, just cutting and reattaching the extensor tendon tightly(tuft) and fixing the joint in extension. Crawford method was used for evaluating the patients. Results : Ten out of eleven patients(91%) came out to be satisfactory according to Crawford method. Excellent in 7 cases, good in 3, fair in 1, respectively. Four patients whose duration between injury and surgery seemed to be too long(4 months, 9 months, 3 years, 7 years respectively), have not showed excellent results. Excellent results were reported in all children. On the contrary, the age of the patient who had the poorest result was 48 years(the oldest in our series) Which hands or which fingers were injured seemed to have not made any differences. So as the surgery was performed earlier and the patients were younger, the results were better. Conclusion : We advocate that it is possible to treat operatively and to get good results in Patients with neglected mallet finger deformities. But it should be emphasized that the earlier the operation is performed, and the younger the patients are, the better the results are.

Denis B 형 방출성 골절의 단 이식골을 사용한 전방 유합술시 단 분절 척추경 나사못 고정과 장 분절 척추경 나사못 고정

정영기,김석우 대한척추외과학회 1998 대한척추외과학회지 Vol.5 No.2

Study design : The operative treatment methods of twenty-one patients with Denis type B burst fractures were evaluated according to the level of pedicle screw fixation. Objective : To compare the results of short segment pedicle screw fixation with long segment pedicle screw fixation in Denis type B burst fractures treated anteriorly with short bone graft. Summary of Back ground data : Relatively good results(Short fusion time, good union rate, less loss of lordosis postoperatively etc.) were obtained in long segment fixation group during follow-up period. Methods : Twenty-one patients with Denis B type burst fractures of thoracolumbar and lumbar spine were divided into two groups depend on the level of pedicle screw fixation in operative treatment methods ; one group consisted of 10 cases which were treated by posterior short segment pedicle screw fixation and anterior interbody fusion with short bone graft(Group I : one level above and below posteior pedicle screw fixation of the fracture site and upper end plate of fracture site was fused with autogenous iliac bone or rib to adjacent vertebral body anteriorly through involved disc space) and the other groups consisted of 11 cases which were treated by posterior long segment pedicle screw fixation and anterior interbody fusion with short bone graft (Group II : more than two level above and below posterior pedicle screw fixation of the fracture site and additionally, anterior interbody fusion with short bone graft performed same as Group Ⅰ). Bony union rate, union period, changes of height of bone and disc, kyphotic angle loss, interscrew angle and complications were measured using pre-, post-operative and follow-up radiographs and chart review. Results : Comparing the two groups, there were no significant postoperative and follow-up results in both groups, especially, change of body & disc height, change of kyphotic angle and change of interscrew angle. However, relatively short fusion time, good union rate, less kyphotic angle loss, and low complication rates were obtained and maintained during follow-up period in long segment fixation group(Group Ⅱ). Conclusions : Long segment pedicle screw fixation and anterior interbody fusion with short bone graft group could effectively treat Denis B type burst fractures of thoracolumbar & lumbar spine and maintain their postoperative results during follow up peroid.

Outcome of Multipair Donor Kidney Exchange by a Web-Based Algorithm

Kim, Beom Seok,Kim, Yu Seun,Kim, Soon Il,Kim, Myoung Soo,Lee, Ho Yung,Kim, Yong-Lim,Kim, Chan Duck,Yang, Chul Woo,Choi, Bum Soon,Han, Duck Jong,Kim, Yon Su,Kim, Sung Joo,Oh, Ha-Young,Kim, Dae Joong American Society of Nephrology 2007 Journal of the American Society of Nephrology Vol.18 No.3

<P>Donor kidney exchange is an established method to overcome incompatibility of donor-recipient pairs (DRP). A computerized algorithm was devised to exchange donor kidney and was tested in a multicenter setting. The algorithm was made according to the consensus of participating centers. It makes all possible exchange combinations not only between two incompatible DRP but also circularly among three DRP and selects an optimum set of exchange combinations, considering several factors that can affect the outcome of the exchanged transplant. The algorithm was implemented as a web-based program, and matching was performed five times. Fifty-three DRP were enrolled from five transplant centers. The numbers of DRP that were enrolled in each matching were 38 (25:13), 39 (34:5), 33 (31:2), 32 (28:4), and 34 (30:4) (carryover:newcomer). The numbers of generated exchange combinations were 4:11, 3:17, 2:12, 2:3, and 2:3 (two-pair exchange:three-pair exchange), and the numbers of DRP in selected exchange combinations were six, 12, six, five, and four in each matching. The numbers of DRP with blood type O recipient or AB donor were five and one, respectively, in selected exchange combinations. Six DRP of two-pair exchange combinations and six DRP of three-pair exchange combinations underwent transplantation successfully. Computerized algorithm of donor kidney exchange was tried not only between two incompatible DRP but also circularly among three DRP. It showed that the algorithm has potential to improve the outcome of donor kidney exchange, especially for disadvantaged DRP with blood type O recipients or AB donors.</P>

Metabolic Pathway Signatures Associated with Urinary Metabolite Biomarkers Differentiate Bladder Cancer Patients from Healthy Controls

Kim, Won Tae,Yun, Seok Joong,Yan, Chunri,Jeong, Pildu,Kim, Ye Hwan,Lee, Il-Seok,Kang, Ho-Won,Park, Sunghyouk,Moon, Sung-Kwon,Choi, Yung-Hyun,Choi, Young Deuk,Kim, Isaac Yi,Kim, Jayoung,Kim, Wun-Jae Yonsei University College of Medicine 2016 Yonsei medical journal Vol.57 No.4

<P><B>Purpose</B></P><P>Our previous high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry study identified bladder cancer (BCA)-specific urine metabolites, including carnitine, acylcarnitines, and melatonin. The objective of the current study was to determine which metabolic pathways are perturbed in BCA, based on our previously identified urinary metabolome.</P><P><B>Materials and Methods</B></P><P>A total of 135 primary BCA samples and 26 control tissue samples from healthy volunteers were analyzed. The association between specific urinary metabolites and their related encoding genes was analyzed.</P><P><B>Results</B></P><P>Significant alterations in the carnitine-acylcarnitine and tryptophan metabolic pathways were detected in urine specimens from BCA patients compared to those of healthy controls. The expression of eight genes involved in the carnitine-acylcarnitine metabolic pathway (<I>CPT1A, CPT1B, CPT1C, CPT2, SLC25A20</I>, and <I>CRAT</I>) or tryptophan metabolism (<I>TPH1</I> and <I>IDO1</I>) was assessed by RT-PCR in our BCA cohort (n=135). C<I>PT1B, CPT1C, SLC25A20, CRAT, TPH1</I>, and <I>IOD1</I> were significantly downregulated in tumor tissues compared to normal bladder tissues (<I>p</I><0.05 all) of patients with non-muscle invasive BCA, whereas <I>CPT1B, CPT1C, CRAT</I>, and <I>TPH1</I> were downregulated in those with muscle invasive BCA (<I>p</I><0.05), with no changes in <I>IDO1</I> expression.</P><P><B>Conclusion</B></P><P>Alterations in the expression of genes associated with the carnitine-acylcarnitine and tryptophan metabolic pathways, which were the most perturbed pathways in BCA, were determined.</P>

Lower Levels of Human MOB3B Are Associated with Prostate Cancer Susceptibility and Aggressive Clinicopathological Characteristics

Kim, Eun-Ah,Kim, Ye-Hwan,Kang, Ho Won,Yoon, Hyung-Yoon,Kim, Won Tae,Kim, Yong-June,Yun, Seok-Joong,Moon, Sung-Kwon,Choi, Yung Hyun,Kim, Isaac Yi,Lee, Sang-Cheol,Kim, Wun-Jae The Korean Academy of Medical Sciences 2015 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.30 No.7

Microwave Sintering of Silver Nanoink for Radio Frequency Applications.

Kim, Kwang-Seok,Park, Bum-Geun,Jung, Kwang-Ho,Kim, Jong-Woong,Jeong, Myung Yung,Jung, Seung-Boo American Scientific Publishers 2015 Journal of Nanoscience and Nanotechnology Vol.15 No.3

<P>Microwave sintering is a promising method for low-temperature processes, as it provides advantages such as uniform, fast, and volumetric heating. In this study, we investigated the electrical characteristics of inkjet-printed silver (Ag) circuits sintered by microwaves. The microstructural evolutions of inkjet-printed Ag circuits sintered at various temperatures for different durations were observed with a field emission scanning electron microscope. The electrical properties of the inkjet-printed Ag circuits were analysed by electrical resistivity measurements and radio frequency properties including scattering-parameters in the frequency range of 20 MHz to 20 GHz. The experimental results show that the signal losses of the Ag circuits sintered by microwave heating were lower than those sintered by conventional heating as microwave heating led to granular films which were nearly fully sintered without pores on the surfaces. When the inkjet-printed Ag circuits were sintered by microwaves at 300 °C for 4 min, their electrical resistivity was 5.1 µ곽 cm, which is 3.2 times larger than that of bulk Ag. Furthermore, microwave sintering at 150 °C for 4 min achieved much lower signal losses (1.1 dB at 20 GHz) than conventional sintering under the same conditions.</P>

Amiodarone에 의한 폐독성 1예

김인기,정병오,이혁표,김주인,염호기,최수전,김두일,김동수,양영일,최석진 인제대학교 1999 仁濟醫學 Vol.20 No.1

저자들은 심실성 빈맥으로 amiodarone 일일 400mg을 약 1년 6개월 정도 사용해 오던 환자에서, amiodarone에 의해 유발된 간질성 폐렴 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Amiodarone is a very effective antiarrhythmic agent frequently employed in patient with life-threatening supraventircular tachycardia and ventricular tarchycardia. But amiodarone is associated with a number of side effect, which include liver dysfunction, hyper- and hypothyroidism, bluish discoloration of skin, bone marrow suppression, coagulopathies, peripheral neuropathy, and others. The most serious adverse effect is a pulmonary toxicity which occurs in average 4% to 6% of those patients on the drug and maybe fatal. Two possible mechanisms of amiodarone pulmonary toxicity have been suggested, a direct toxic effect or an immune-mediated response. We report a case of patient with amiodarone pulmonary toxicity who has taking 400mg of amiodarone per day for reccurent ventircular tachycardia.

Korean Medical Therapy for Knee Pain after Anterior Cruciate Ligament Reconstruction

Kim, Hye Ryeon,Choi, Yu Na,Kim, Seon Hye,Kang, Ha Ra,Lee, Yoon Joo,Jung, Chan Yung,Cho, Hyun Seok,Kim, Kyung Ho,Kim, Kap Sung,Kim, Eun Jung Korean AcupunctureMoxibustion Medicine Society 2017 대한침구의학회지 Vol.29 No.3

Objectives : The aim of this study was to report the effect of Korean medical therapy on pain and dysfunction after anterior cruciate ligament (ACL) reconstruction. Methods : A 25-year-old man experienced severe pain after right ACL reconstruction surgery. He received Korean medical treatments such as acupuncture, herbal medicine, and physiotherapy from July 10, 2014 to August 2, 2014. Results : After the treatments, his visual analogue scale scores generally decreased and the range of motion of the right knee improved from $0^{\circ}$ to $90^{\circ}$. Furthermore, the Knee Infury and Osteoarthritis Outcome Score increased from 99 to 142. Conclusion : The findings suggest that Korean medical treatments might be effectively used to treat pain and dysfunction after soft-tissue surgeries such as ACL reconstruction. Nevertheless, further research is warranted because of the limited sample size of this study.