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( Parul Kodan ),( Jayakumar J ),( Seemanthani T S ),( Sydney Dsouja ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1
Background: With diabetes rapidly affecting even the younger population makes it alarming for the physicians to understand its various complications. Although the effects of DM on peripheral nervous system are well established, the effects of Diabetes(DM) on CNS have been less clear. Even a modest effect on cognitive function will have signifi cant public health implications. Our study is one of the unique study from Indian subcontinent where we aimed to compare the memory profi le of 30-55 years old men with Type II DM with age matched controls and to fi nd whether any relationship exists between DM control and memory function in this age group. Methods: The study design was a cross sectional clinical study of Diabetic males of age group 30-55 years and age matched controls for memory testing. The study included men of 30-55 years diagnosed to have Type 2 DM.All patients with previous neurological disorders or hypothyroidism were excluded. All patients,after valid consent, were tested for memory testing using PGI Memory Scale. Test was objectively scored scores and ranged from 0-100.All patients with Diabetes were also tested for HbA1c. Results: Average memory score in case group was 80.76±8.75 and it was 87.68±7.39 in control group which was statistically signifi cant showing better memory scoring in control group. When long term diabetes control was compared it was seen that there is a trend of higher HbA1c having poor memory scoring. Conclusions: Our study showed presence of mild cognitive impairment in young males with diabetes which is an alarming revelation. This pathbreaking fi nding is an alarming indication to the clinicians and neurologist to look for this complication in young patients of diabetes. Also our study showed trend of higher HbA1c had poor memory scoring underscoring the importance of strict diabetes control especially in young diabetes.