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1
What is the Role of Collectivism in Channel Marketing?

( Junhyuk Suh ),( Boa Son ) 서암순창장학회 2016 Journal of Marketing Thought Vol.3 No.1
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- 복사/대출신청
Our study aims to explore the role of collectivism in the field of channel marketing. We think collectivism is an important organization of culture beyond the national level and a main element in network embeddedness, group norms, and sense of community. Specifically, herein, we analyzed the source of network embeddedness and redefined group norms in a multidimensional setting. Also, we propose that the group norms and sense of community are the main effects of network embeddedness. Hypotheses based on these ideas were tested with 100 managers of large Korean companies. Our results show that collectivism as an organizational culture had a positive effect on network embeddedness, group norms, and sense of community. Moreover, network embeddedness had a positive effect on the sense of community, but it did not influence group norms positively. We discuss our findings and their implications.
2
Enhanced Glycolysis Supports Cell Survival in EGFR-Mutant Lung Adenocarcinoma by Inhibiting Autophagy-Mediated EGFR Degradation

Kim, Ji Hye,Nam, Boas,Choi, Yun Jung,Kim, Seon Ye,Lee, Jung-Eun,Sung, Ki Jung,Kim, Woo Sung,Choi, Chang-Min,Chang, Eun-Ju,Koh, Jae Soo,Song, Joon Seon,Yoon, Shinkyo,Lee, Jae Cheol,Rho, Jin Kyung,Son, American Association for Cancer Research 2018 Cancer Research Vol.78 No.16
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Enhanced glycolysis by EGFR mutation is required for maintaining EGFR levels via inhibition of JNK-induced autophagy. This provides a promising rationale for use of JNK activators in patients with EGFR-mutated NSCLC.Oncogenic EGFR is essential for the development and growth of non–small cell lung cancer (NSCLC), but the precise roles of EGFR in lung cancer metabolism remain unclear. Here, we show that EGFR mutation-mediated enhancement of glycolysis is critical for EGFR stability. EGFR knockdown significantly decreased levels of glycolytic pathway intermediates via transcriptional regulation of glycolytic genes. EGFR mutation-enhanced glycolysis was required for fueling the tricarboxylic acid cycle, a critical component of EGFR stability. Nonsustained ATP production enhanced reactive oxygen species accumulation and subsequent JNK-mediated activation of autophagy, which in turn induced EGFR degradation. Our data show that EGFR-mutant NSCLCs require EGFR mutation-enhanced glycolysis to maintain EGFR stability. This pathway may serve as an attractive therapeutic target for EGFR-mutant NSCLCs.Significance: Enhanced glycolysis by EGFR mutation is required for maintaining EGFR levels via inhibition of JNK-induced autophagy. This provides a promising rationale for use of JNK activators in patients with EGFR-mutated NSCLC. Cancer Res; 78(16); 4482–96. ©2018 AACR.
3
Impact of News Content on Ratings and Advertising Revenue: A Case of YTN News Channel

( Hae-gin Youm ),( Boa Son ) 서암순창장학회 2016 Journal of Marketing Thought Vol.2 No.4
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- 복사/대출신청
This study is to identify what impact the news contents has on the viewing ratings and what changes they this con-tent has brought to advertising revenue based on the computerized records from the Press Information System to YSYS-s on the basis of which YTN as a specialized news channels produce and maintain the news contents which is the core products. It was a difficult situation for data collection proved difficult due to having overlooked the statis-tical functions with the introduction of the Press Information System. Especially, it had been operated in integration without boundaries of classifications when organizing the Newsflash with only one issue for a long period of time when a large event or accident occurred. Due to the limitations, the study could not analyze what impacts the News-flashes haves on the viewing ratings and advertising revenue, due to data separation problems. The issues are obliged to be excluded from the survey scope.