단순 신낭종과 고혈압의 상관관계 분석

다국어 초록 (Multilingual Abstract)

Purpose: Simple renal cyst (SRC) has been associated with hypertension, although there is little evidence to support such a relationship in large healthy screened populations. To assess the impact of SRC on hypertension, we evaluated the prevalence of SRC as well as the relationship between SRC and hypertension in our institution’s Health Promotion Center patient cohort.
Materials and Methods: Data were obtained from 29,666 patients who underwent general health-screening tests between January 2006 and December 2006 at the Asan Medical Center Health Promotion Center. Only patients who underwent contrast-enhanced computed tomography (CT) scanning or abdominal ultrasonography were included in our study population. We then correlated the clinical characteristics and parameters of hypertension with the presence or absence of renal cysts.
Results: Of all the enrolled patients, 5,674 (19.2%) had radiologic evidence of SRC and hypertension was diagnosed in 9,865 participants (33.4%). Age, sex, BMI, and SRC were independent risk factors for hypertension. The SRC had a multivariable adjusted odds ratio (OR) of 1.16 (95% confidence interval [CI], 1.09-1.23) for the presence of hypertension. In study participants with multiple cysts (>1), a large cyst (≥4 cm in diameter) or a peripheral cyst location, the ORs for the presence of hypertension were 1.31 (95% CI, 1.19-1.44), 1.29 (95% CI, 1.06-1.56), and 1.33 (95% CI, 1.11-1.64), respectively, compared with those for study participants without cyst after adjusting for other variables.
Conclusions: We found the presence of SRC to be associated with a significantly increased incidence of hypertension. In addition, the cyst number, size, and location are important characteristics of SRC related to hypertension.

목차 (Table of Contents)

• 영문요약 i
• 표 차례 iii
• 그림차례 iv
• 서론 1
• 연구대상 및 방법 2
• 결과 4
• 고찰 6
• 결론 9
• 참고문헌 10
• 국문요약 19