규칙적인 운동참여 노인에 있어 안지오텐신 전환효소 유전자의 다형성별 체력 상태와 우울증의 차이 = Difference of physical fitness and depression degree on insertion/deletion polymorphism of angiotensin converting enzyme gene in regularly exercising elderly

다국어 초록 (Multilingual Abstract)

The purpose of this study was to investigate to differences of physical fitness and depression degree on insertion/deletion polymorphism of angiotensin converting enzyme(ACE) gene in regularly exercising elderly. The subjects of this study were 60 women residing Seoul-Seniors-Tower. All of subjects divided to two groups, one group or exercise group 27 was participating in an exercise program for 1 years, and the other group or non-exercise group 33 was not in that program. The result swere as followed: 1) The rates of insertion/deletion polymorphism of ACE gene in all the subjects were 12% in II-type on exercising group, 13% in II-type on non-exercising group, 22% in ID-type on exercising group, 26% in ID-type on non-exercising group, and 12% in DD-type on exercising group, 15% in DD-type on non-exercising group respectively. 2) Although the comparative results of physical fitness in all of the subjects represented significantly different in cardiopulmonary endurance, systolic blood pressure(SBP), fat mass, and %fat, there was not significantly difference in depression scale. 3) Although the comparative results of physical fitness within an exercised group represented significantly different in cardiopulmonary endurance, strength, fat mass, and %fat, there was not significantly difference in depression scale. Also the comparative results of physical fitness within an non-exercised group represented significantly different in cardiopulmonary endurance and fat mass, and the II-type was superior to the other types. 4) The comparative results of physical fitness and depression between groups(classified by exercised or non-exercised groups) represented as follows: there were significantly differences in cardiopulmonary endurance, SBP, DBP, biceps' endurance, strength, %fat, and depression degrees on II-type group. There were significantly differences in cardiopulmonary endurance, SBP, DBP, legs' endurance, flexibility, fat mass, and %fat on ID-type group. At last, there were significantly differences in cardiopulmonary endurance, fat mass, %fat and depressiondegrees on DD-type group. As a conclusion, this paper showed that although the regular exercise could increase the fitness levels or improve the depression in elderly women, these results were partly positive to the variables.

목차 (Table of Contents)

• 목차 = i
• I. 서론 = 1
• 1. 연구의 필요성 = 1
• 2. 연구의 목적 = 3
• 3. 연구의 가설 = 3
• 4. 연구의 제한점 = 4
• II. 이론적 배경 = 5
• 1. 안지오텐신 전환효소 유전자 = 5
• 2. 노인의 정의와 특성 = 8
• 3. 노인의 체력적 특성 = 10
• 가. 노인에 있어 체력의 변화 = 10
• 나. 노인에 있어 신체구성의 변화 = 13
• 4. 노인과 우울증 = 15
• III. 연구 방법 = 18
• 1. 연구 대상 = 18
• 2. 실험 방법 = 19
• 가. 실험 절차 = 19
• 나. 운동프로그램 = 20
• 3. 측정 방법 = 21
• 가. ACE 유전자 측정 및 분석방법 = 21
• 나. 운동부하검사와 심폐지구력 측정 = 23
• 다. 체력 검사 = 25
• 라. 우울증 측정 = 27
• 4. 측정 도구 = 30
• 5. 자료처리 방법 = 30
• IV. 연구 결과 = 32
• 1. ACE 유전자의 다형성별 분포도 = 32
• 2. 전체 ACE 유전자 유형별 체력요소와 우울증의 비교 = 33
• 3. 집단 내 ACE 유전자 유형별 체력요소와 우울증의 비교 = 49
• 4. ACE 유전자 유형별 집단 간 체력요소와 우울증의 비교 = 68
• V. 논의 = 73
• VI. 결론 = 77
• 참고문헌 = 80
• ABSTRACT = 94