시험 스트레스시 적대감이 혈청 코르티솔 농도와 혈압 및 맥박에 미치는 영향 = Effects of Hostility on Serum Cortisol Levels, Blood Pressure and Pulse Rate under Examination Stress

다국어 초록 (Multilingual Abstract)

This study was designed to test the hypothesis that the students with high hostility scores were associated with higher serum cortisol vlevels, and higher responsivity of blood pressure and pulse rate, under the written examination stress in comparison to the students with lower hostility scores.
Fifty two medical students gave informed consents to participate in the study. Hostility levels were measured by the Cook-Medley hostility scale, and the response variables were serum cortisol, systolic and diastolic blood pressures, and pulse rates. Coo-Medley hostility scale were administered about one month prior to examination, Serum cortisol levels, systolic and diastolic blood pressures, and pulse rats were measured three times durung the experimental period, about one month before examination, during examination and about one month after examination, respectively. Serum cortisol levels were measured in duplicates by the Coat-A-count radioimmunoassay procedure(??I) and blood presures and pulse rates were measured by two standardized automatic sphygomomanometers.
The response variables compatible with the hypothesis were serum cortisol and pulse rate in Cook-Medley hostility tatal scores where serum cortisol concentration of the student with low total scores was 9.43±μ21.82 g/dl and that of the students with high total scores was 9.56 ±2.97 ㎍/dl before examintion. The former showed little changes(9.36±2.34 ㎍/dl) but the latter did a marked increase(11.14±2.14 ㎍/dl) during examination and the serum cortisol levels of both returned to the baseline levels after examination(Period and periodXsubjects effects, p<0.05). And serum cortisol in cynicism subsets and pulse rate in paraniod aliennation subset of Costa et al's two subsets and serum cortisol, systolic blood pressure in social avoidance subset of Barefoot et al's six subsets were compatible with the hypothesis. Serum cortisol levels showed a borderline significance with cynicism subset of Barefoot et al's (0.05<p<0.1).
These results suggest that total scores and some subsets of Cook-Medley's hostility scale may be involved in the biomechanism between hostility and coronary heart disease.