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      이황화탄소를 경구투여한 흰쥐의 혈중 이황화탄소에 관한 연구 = The Study of Blood Carbon Disulfide in rats After Oral Administration of Carbon Disulfide

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      https://www.riss.kr/link?id=A1991645

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      Carbon disulfide (CS₂) ditributed in the body by the blood stream, presents free form and bound form carbon disulfide that is acid-labile carbon disulfide(ALCS₂) in blood. ALCS₂could be analyzed by acid-treatment fraction which binds to celluar macromolecules or amino acid. We observed the variation of blood concentration of carbon disulfide and the amounts of free form CS₂and ALCS₂in blood were determined according to their oral doses. After administration for six days, the amount of free form CS₂and ALCS₂in blood was increased significantly through duration of administration for six days. ALCS₂was remained longer than free form CS₂in blood for all doses. The amount of free form CS₂and ALCS₂in red blood cells was larger than that of plasma. As the above results, ALCS₂might be a useful indicator for biological monitoring of CS₂in blood.
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      Carbon disulfide (CS₂) ditributed in the body by the blood stream, presents free form and bound form carbon disulfide that is acid-labile carbon disulfide(ALCS₂) in blood. ALCS₂could be analyzed by acid-treatment fraction which binds to celluar ...

      Carbon disulfide (CS₂) ditributed in the body by the blood stream, presents free form and bound form carbon disulfide that is acid-labile carbon disulfide(ALCS₂) in blood. ALCS₂could be analyzed by acid-treatment fraction which binds to celluar macromolecules or amino acid. We observed the variation of blood concentration of carbon disulfide and the amounts of free form CS₂and ALCS₂in blood were determined according to their oral doses. After administration for six days, the amount of free form CS₂and ALCS₂in blood was increased significantly through duration of administration for six days. ALCS₂was remained longer than free form CS₂in blood for all doses. The amount of free form CS₂and ALCS₂in red blood cells was larger than that of plasma. As the above results, ALCS₂might be a useful indicator for biological monitoring of CS₂in blood.

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