Objectives:We examined the impact of 12-session group cognitive behavioral trerapy(GCBT) on
quality of life in patients with panic disorder, and also investigated correlation with the change of
some clinical characteristics.
Methods:Patients(N=108...
Objectives:We examined the impact of 12-session group cognitive behavioral trerapy(GCBT) on
quality of life in patients with panic disorder, and also investigated correlation with the change of
some clinical characteristics.
Methods:Patients(N=108) who met DSM-IV criteria for panic disorder with or without agoraphobia
were treated by 12-session GCBT. We assessed the quality of life using SF-36 and some clinical
characteristics including symptom profiles. We measured anxiety and depression levels using the Spielberger
State-Trait Anxiety Inventory(STAI) and the Beck Depression Inventory(BDI), and also measured
some cognitive behavioral indexes typically found in panic patients using the Anxiety Sensitivity
Index(ASI), the Agoraphobic Cognition Questionnaire(ACQ), the Panic Belief Questionnaire(PBQ),
and the Body Sensation Questionnaire(BSQ).
Results:GCBT-treated patients showed significant improvement in quality of life in all subscales
of SF-36(general health, t=-5.23;, physical functioning, t=-5.89;, role physical, t=-3.67;, body
pain, t=-6.36;, vitality t=-8.29;, social functioning, t=-6.56;, role emotion, t=-3.62;, mental
health, t=-6.81). Multiple regression analysis showed that the change of anxiety sensitivity was the
best predictor of the improvement of SF-36(mental health, R2=.19, p<0.001;, vitality, R2=.14, p<0.001;,
social functioning, R2=.15, p<0.001). Otherwise the change of panic belief(general health, R2=.11, p<
0.01;, body pain, R2=15, p<0.001), BDI(role emotion, R2=.08, p<0.05) could explain the improvement
of one of subscales of SF-36.
Conclusion:Our results suggested that 12-session GCBT could significantly improve quality of
life in patients with panic disorder. Especially, the reduction of anxiety sensitivity, panic belief and
depression with the correction of cognitive distortion and sensitivity might play an important role in
improving quality of life in panic patients.