Antioxidative Phenolic Compounds from the Whole Plant of Juncus diastrophanthus = Antioxidative Phenolic Compounds from the Whole Plant of Juncus diastrophanthus

다국어 초록 (Multilingual Abstract)

Methanol extract of Juncus diastrophanthus (Juncaceae) was found to show potent antioxidant activity. Subsequent activity-guided fractionation of methanol extract of J. diastrophanthus led to the isolation of seven flavonoid compounds, isorhamnetin-3-O-α-L-rhamnopyranosyl(1→6)-β-Dglucopyranoside, narcissin (1), quercetin-3-O-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside, rutin (2), kaempferol-3-O-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside (3), quercetin (4), quercetin-3-O-α-L-rhamnopyranoside, quercitrin (5), quercetin-3-O-β-D-xylopyranoside (6), and luteolin (7). These compounds were isolated for the first time from this plant. Compounds 4 and 7 showed significant antioxidative effects on 1,1-diphenyl-2-picrylhydrazyl, and compound 5 showed significant riboflavin-originated superoxide and xanthine-originated superoxide quenching activities.

참고문헌 (Reference)

1 Sun-Ha Choi, "β-Secretase (BACE1) Inhibitors from Perilla frutescens var. acuta" 대한약학회 31 (31): 183-187, 2008

2 Branen AL, "Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene" 52 : 59-63, 1975

3 Mabry TJ, "The ultraviolet spectra of flavones and flavonols. In the Systematic Identification of Flavonoids" Springer 41-164, 1970

4 Liu J, "The antioxidant and free-radical scavenging activities of extract and fractions from corn silk(Zea mays L.)and related flavone glycosides" 126 : 261-269, 2011

5 Ginnopolitis CN, "Superoxide dismutase.I.Occurrence in higher plants" 59 : 309-314, 1977

6 Shan CY, "Study on Chemical Constituents Isolated from Juncus effuses" 31 : 374-376, 2008

7 Yoshida T, "Studies on inhibition mechanism of autooxidation by tannins and flavonoids.V.Radical scavenging effects of tannins and related polyphenols on 1,1-diphenyl-2-picrylhydrazyl radical" 37 : 1919-1921, 1989

8 Choi JS, "Phenolic Compounds of the roots of Bupleurum longeradiatum" 12 : 226-228, 1989

9 Behery FAA, "Phenanthrenoids from Juncus acutus L.,new natural lipopolysaccharide-inducible nitric oxide synthase inhibitors" 55 : 1264-1266, 2007

10 Noipa T, "New approach for evaluation of the antioxidant capacity based on scavenging DPPH free radical in micelle systems" 44 : 798-806, 2011

11 Agrawal PK, "NMR spectroscopy in the structural elucidation of oligosaccharides and glycosides" 31 : 3307-3330, 1992

12 Li HX, "Isolation and identification of phenolic constituents from Juncus effusus" 42 : 174-178, 2007

13 Choi DS, "Inhibitory activity of berberine on DNA strand cleavage induced by hydrogen peroxide and cytochrome c" 65 : 452-455, 2001

14 이사임, "Free Radical Scavengers from the Fruits of Paeonia suffruticosa" 한국생약학회 14 (14): 202-205, 2008

15 Agrawal PK, "Flavonoids. In Carbon-13 NMR of Flavonoids" Elsevier 154-155, 1989

16 Whang WK, "Flavonoids from the aerial part of Aconitum jaluense for.album" 25 : 336-341, 1994

17 Sharma OP, "DPPH antioxidant assay revisited" 113 : 1202-1205, 2009

18 Ju Sun Kim, "Chemical Constituents of the Root of Dystaenia takeshimana and Their Anti-Inflammatory Activity" 대한약학회 29 (29): 617-623, 2006

19 Markham KR, "Carbon-13 NMR studies of flavonoids-III,naturally occurring flavonoid glycosides and their acylated derivatives" 34 : 1389-1397, 1978

20 Hyunjin Lee, "Antioxidative Constituents of Cyperus difformis L" 한국생약학회 15 (15): 241-245, 2009

21 Dae Keun KIM, "Antioxidative Constituents from the Twigs of Vitex rotundifolia" 한국응용약물학회 17 (17): 412-417, 2009

22 Wu SJ, "Antioxidant and free radical scavenging activities of wild bitter melon(Momordica charantia Linn.var.abbreviata Ser.)in Taiwan" 41 : 323-330, 2008

23 Dae Keun KIM, "Antioxidant Flavonoids from the Twigs of Stewartia koreana" 한국응용약물학회 18 (18): 191-196, 2010

24 "Anti-oxidant constituents from Sedum takesimense" 68 : 2432-2438, 200710

25 Hyun-Woo Lim, "Anti-Oxidative and Nitric Oxide Production Inhibitory Activities of PhenolicCompounds from the Fruits of Actinidia arguta" 한국생약학회 12 (12): 221-225, 2006