The Korean Society of Gastroenterology& SLDDS 2033 : Slide Session ; K-BP-23 : Pancreatobiliary ; Detection of Malignancy and Natural Course of Incidental Pancreatic Cystic Neopla는 = The Korean Society of Gastroenterology& SLDDS 2033 : Slide Session ; K-BP-23 : Pancreatobiliary ; Detection of Malignancy and Natural Course of Incidental Pancreatic Cystic Neopla는

다국어 초록 (Multilingual Abstract)

Background: Although some pancreatic cystic neoplasms(PCNs) is a surgical indication, slow-growing and favorable prognosis have been suggested in contrast to ductal adenocarcinomas. The aim of this study was to evaluate natural course of PCNs and the detection of malignant transformation according to risk factor during follow up. Methods: We retrospectively reviewed a record of patients diagnosed with incidental PCNs from March 2000 to June 2013 in Guro and Anam hospital, Korea University College of Medicine, Seoul. Results: Of enrolled 301 patients, 19 patients were excluded (15 patients with less than 1 year of follow up, 4 patients with operation due to malignancy at initial cyst diagnosis). Data from total 282 patients was analyzed (Mean age: 59.4 years, median follow up: 28.5 months) and 97 patients had the risk factors such as more than 3cm in diameter or presence of mural nodule/solid portion. 41 patients (41/282, 14.5%) had changes in followed imaging CT (median duration of event in follow up imaging was 24 months), 32 cases showed increase of size and 9 cases changed in characteristics of cyst. Cyst-related malignancy was occurred in 5 patients (1.8%, 5/282). All these patients had risk factor and increase of size. Post-operative morbidity was observed in 31 of 93 cases (33.3%). 2 patients were died (1; intra-abdominal infection, 1; mechanical obstruction due to post operative adhesion). Motality during study period was in 9 patients but disease specifi c mortality was only one patient. Conclusions: Although the risk of malignant transformation of incidental PCNs was higher than the general population, detection of malignancy or disease specifi c mortality during surveillance was low, even if high risk group. Under surveillance the regular imaging follow up is seemed to be important especially in 2 years after initial cyst diagnosis.