The Korean Society of Gastroenterology& SLDDS 2032 : Slide Session ; K-BP-22 : Pancreatobiliary ; Optimal Follow-Up and Long-Term Clinical Outcome of Pancreatic Cystic Lesions = The Korean Society of Gastroenterology& SLDDS 2032 : Slide Session ; K-BP-22 : Pancreatobiliary ; Optimal Follow-Up and Long-Term Clinical Outcome of Pancreatic Cystic Lesions

다국어 초록 (Multilingual Abstract)

Background: Although it is generally accepted that cystic lesions in the pancreas (CLPs) 3 cm or less in size and without features suggesting malignancy can be managedconservatively with follow-up, the optimal duration and interval of follow-up for CLPs is not yet well established. Methods: Patients with CLPs 3 cm or less in size and without features suggesting malignancy received follow-up with computed tomography at 6, 12, 18, and 24 months and then per 12 months. A retrospective analysis with prospectively collected data was performed. Results: A total of 205 patients with CLPs detected from 2004 to 2009 (initial mean size, 1.8±0.7 cm) received follow-up during the median period of 56.6 months. Within the fi rst 12 months of follow-up, no patients experienced the growth of cyst and three patients (1.5%) underwent surgery for the presence of symptoms related to CLPs. 11 patients (5.4%) experienced the growth of cyst after 5 years of follow-up. A total of 18 patients underwent surgery during follow-up and four malignant cysts were detected. Overall rate of malignant progression during follow-up was 2.0%. The malignant progression occurred after 48 months and 60 months of follow-up in one and three patients, respectively. Conclusions: Long-term follow-up more than 5 year should be performed because of the potential for malignant transformation of CLPs. The 12 months interval of follow- up for asymptomatic CLPs might be suffi cient in clinical practice.