Lymphoepithelial cysts are lesions lined by stratifi ed squamous epithelium and surrounded by lymphoid tissue, resembling a lymph node. They are rare developmental lesions and etiopathogenesis is unclear. They are often found in the lateral neck or in...
Lymphoepithelial cysts are lesions lined by stratifi ed squamous epithelium and surrounded by lymphoid tissue, resembling a lymph node. They are rare developmental lesions and etiopathogenesis is unclear. They are often found in the lateral neck or in the parotid gland and rarely occur in the esophagus. Our case is of particular interest because it is a case of multiple lymphoepithelial cysts in the upper esophagus. A 51-year-old women received esophagogastroduodenoscopy as part of a physical check-up and was referred to our hospital with a suspected esophageal submucosal tumor. The patient was in good health without any symptoms and had neither past medical history nor family history. There was no specifi c fi nding on physical examination and laboratory findings were within normal limits. Endoscopic examination revealed three small submucosal tumors on the upper esophagus; 18cm, 17cm, and 16cm from the incisors. Endoscopic ultrasonography(EUS) revealed 4. 8mm (16cm from incisor), 3. 4mm (17cm from incisor), and 5. 1mm (18cm from incisor) sized homogenous hypoechoic tumors with central foci on the second layer of upper esophagus. We diagnosed them as esophageal leiomyomas and planned to perform EUS every 6 months. In next follow-up EUS, the size of three tumors were increased; 5. 6mm (16cm from incisor), 4. 1 mm(17cm from incisor), and 4. 5 mm(18cm from incisor). They were removed by endoscopic mucosal resection to confi rm diagnosis of these lesions. Each of tumors had same pathological fi nding; a cyst lined by stratifi ed squamous epithelium and surrounded by lymphoid tissue with germinal centers. Based on this fi nding, we diagnosed these lesions as multiple lymphoepithelial cysts of the upper esophagus. After procedure, the patient was tolerable and discharged well. And in follow-up endoscopy after 3 months, there was no remnant submucosal lesion and she was reserved to receive follow-up endoscopy every 1 year.